| The human cathelicidin antimicrobial peptide LL-37 as a potential treatment for polymicrobial infected wounds AJ Duplantier, ML van Hoek Frontiers in immunology 4, 143, 2013 | 297 | 2013 |
| Biarylcarboxylic Acids and -amides: Inhibition of Phosphodiesterase Type IV versus [3H]Rolipram Binding Activity and Their Relationship to Emetic Behavior in … AJ Duplantier, MS Biggers, RJ Chambers, JB Cheng, K Cooper, ... Journal of medicinal chemistry 39 (1), 120-125, 1996 | 174 | 1996 |
| Discovery, SAR, and Pharmacokinetics of a Novel 3-Hydroxyquinolin-2(1H)-one Series of Potent d-Amino Acid Oxidase (DAAO) Inhibitors AJ Duplantier, SL Becker, MJ Bohanon, KA Borzilleri, BA Chrunyk, ... Journal of medicinal chemistry 52 (11), 3576-3585, 2009 | 136 | 2009 |
| Catechol diethers as selective PDEIV inhibitors AJ Duplantier, JF Eggler, A Marfat, H Masamune US Patent 5,814,651, 1998 | 101 | 1998 |
| Discovery of 4-(5-Methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a Novel α7 Nicotinic Acetylcholine Receptor Agonist for the … CJ O’Donnell, BN Rogers, BS Bronk, DK Bryce, JW Coe, KK Cook, ... Journal of medicinal chemistry 53 (3), 1222-1237, 2010 | 100 | 2010 |
| Nicotinamide derivatives A Marfat, RJ Chambers, JW Watson, JB Cheng, AJ Duplantier, ... US Patent 6,380,218, 2002 | 84 | 2002 |
| Mitigating the impact of antibacterial drug resistance through host-directed therapies: current progress, outlook, and challenges CY Chiang, I Uzoma, RT Moore, M Gilbert, AJ Duplantier, RG Panchal MBio 9 (1), 10.1128/mbio. 01932-17, 2018 | 76 | 2018 |
| Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candidate CE … AJ Duplantier, MA Dombroski, C Subramanyam, AM Beaulieu, SP Chang, ... Bioorganic & medicinal chemistry letters 21 (12), 3708-3711, 2011 | 76 | 2011 |
| Discovering drugs for the treatment of Ebola virus SL Bixler, AJ Duplantier, S Bavari Current Treatment Options in Infectious Diseases 9, 299-317, 2017 | 72 | 2017 |
| Triple asymmetric synthesis for fragment assembly: validity of approximate multiplicativity of the three diastereofacial selectivities AJ Duplantier, MH Nantz, JC Roberts, RP Short, P Somfai, S Masamune Tetrahedron letters 30 (52), 7357-7360, 1989 | 66 | 1989 |
| Pulmonary eosinophilia in a murine model of allergic inflammation is attenuated by small molecule α4β1 antagonists E Kudlacz, C Whitney, C Andresen, A Duplantier, G Beckius, L Chupak, ... Journal of Pharmacology and Experimental Therapeutics 301 (2), 747-752, 2002 | 62 | 2002 |
| Triazolo-pyridines anti-inflammatory compounds KF McClure, MA Letavic, MA Dombroski, AJ Duplantier, ER Laird US Patent 6,696,464, 2004 | 60 | 2004 |
| Recent successes in therapeutics for Ebola virus disease: no time for complacency PL Iversen, CD Kane, X Zeng, RG Panchal, TK Warren, SR Radoshitzky, ... The Lancet Infectious diseases 20 (9), e231-e237, 2020 | 54 | 2020 |
| Synthesis and in vitro profile of a novel series of catechol benzimidazoles. The discovery of potent, selective phosphodiesterase type IV inhibitors with greatly attenuated … JB Cheng, K Cooper, AJ Duplantier, JF Eggler, KG Kraus, SC Marshall, ... Bioorganic & Medicinal Chemistry Letters 5 (17), 1969-1972, 1995 | 51 | 1995 |
| Pimaricin. Stereochemistry and synthesis of its aglycon (pimarolide) methyl ester AJ Duplantier, S Masamune Journal of the American Chemical Society 112 (19), 7079-7081, 1990 | 51 | 1990 |
| 7-Oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridines as Novel Inhibitors of Human Eosinophil Phosphodiesterase AJ Duplantier, CJ Andresen, JB Cheng, VL Cohan, C Decker, ... Journal of medicinal chemistry 41 (13), 2268-2277, 1998 | 49 | 1998 |
| 1-[(1-Methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 Positive Allosteric Modulators for the Treatment of Psychosis L Zhang, MA Brodney, J Candler, AC Doran, AJ Duplantier, IV Efremov, ... Journal of medicinal chemistry 54 (6), 1724-1739, 2011 | 44 | 2011 |
| Modulation of NMDA receptor function by inhibition of D-amino acid oxidase in rodent brain CA Strick, C Li, L Scott, B Harvey, M Hajós, SJ Steyn, MA Piotrowski, ... Neuropharmacology 61 (5-6), 1001-1015, 2011 | 41 | 2011 |
| Benzimidazolyl compounds I Efremov, BN Rogers, AJ Duplantier, L Zhang, Q Zhang, NS Maklad, ... US Patent App. 11/780,579, 2008 | 41 | 2008 |
| Non-peptidyl inhibitors of VLA-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases AJ Duplantier, LS Chupak, AJ Milici, WF Lau US Patent 6,668,527, 2003 | 40 | 2003 |
Monique van HoekSchool of Systems Biology, Center for Infectious Disease Research, George Mason University在 gmu.edu 的电子邮件经过验证
Monique van HoekSchool of Systems Biology, Center for Infectious Disease Research, George Mason University在 gmu.edu 的电子邮件经过验证