Drug‐induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine S Rajamani, LL Eckhardt, CR Valdivia, CA Klemens, BM Gillman, ... British journal of pharmacology 149 (5), 481-489, 2006 | 237 | 2006 |
Variants in the 3′ untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an … AS Amin, JR Giudicessi, AJ Tijsen, AM Spanjaart, YJ Reckman, ... European heart journal 33 (6), 714-723, 2012 | 174 | 2012 |
Right ventricular failure following chronic pressure overload is associated with reduction in left ventricular mass: evidence for atrophic remodeling M Hardziyenka, ME Campian, HJ Reesink, S Surie, BJ Bouma, ... Journal of the American College of Cardiology 57 (8), 921-928, 2011 | 130 | 2011 |
Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome AS Amin, LJ Herfst, BP Delisle, CA Klemens, MB Rook, CR Bezzina, ... The Journal of clinical investigation 118 (7), 2552-2561, 2008 | 115 | 2008 |
Fever-triggered ventricular arrhythmias in Brugada syndrome and type 2 long-QT syndrome AS Amin, CA Klemens, PG Meregalli, A Asghari-Roodsari, JMT de Bakker, ... Netherlands Heart Journal 18 (3), 165-169, 2010 | 74 | 2010 |
Sudden cardiac arrest associated with use of a non-cardiac drug that reduces cardiac excitability: evidence from bench, bedside, and community A Bardai, AS Amin, MT Blom, CR Bezzina, J Berdowski, PNJ Langendijk, ... European heart journal 34 (20), 1506-1516, 2013 | 49 | 2013 |
Slow delayed rectifier potassium current blockade contributes importantly to drug-induced long QT syndrome CC Veerman, AO Verkerk, MT Blom, CA Klemens, PNJ Langendijk, ... Circulation: Arrhythmia and Electrophysiology 6 (5), 1002-1009, 2013 | 48 | 2013 |
Progression of diabetic kidney disease in T2DN rats O Palygin, D Spires, V Levchenko, R Bohovyk, M Fedoriuk, CA Klemens, ... American Journal of Physiology-Renal Physiology 317 (6), F1450-F1461, 2019 | 47 | 2019 |
Ankyrin G expression regulates apical delivery of the epithelial sodium channel (ENaC) CA Klemens, RS Edinger, L Kightlinger, X Liu, MB Butterworth Journal of Biological Chemistry 292 (1), 375-385, 2017 | 37 | 2017 |
Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC) DV Ilatovskaya, V Levchenko, TS Pavlov, E Isaeva, CA Klemens, ... EBioMedicine 40, 663-674, 2019 | 29 | 2019 |
A MicroRNA Cluster miR‐23–24–27 Is Upregulated by Aldosterone in the Distal Kidney Nephron Where it Alters Sodium Transport X Liu, RS Edinger, CA Klemens, YL Phua, AJ Bodnar, WA LaFramboise, ... Journal of cellular physiology 232 (6), 1306-1317, 2017 | 28 | 2017 |
Characterization of purinergic receptor expression in ARPKD cystic epithelia O Palygin, DV Ilatovskaya, V Levchenko, CA Klemens, L Dissanayake, ... Purinergic Signalling 14, 485-497, 2018 | 26 | 2018 |
SGLT2 inhibition effect on salt-induced hypertension, RAAS, and Na+ transport in Dahl SS rats O Kravtsova, R Bohovyk, V Levchenko, O Palygin, CA Klemens, T Rieg, ... American Journal of Physiology-Renal Physiology 322 (6), F692-F707, 2022 | 24 | 2022 |
Role of opioid signaling in kidney damage during the development of salt-induced hypertension D Golosova, O Palygin, R Bohovyk, CA Klemens, V Levchenko, ... Life Science Alliance 3 (12), 2020 | 21 | 2020 |
Postprandial effects on ENaC-mediated sodium absorption G Blass, CA Klemens, MW Brands, O Palygin, A Staruschenko Scientific reports 9 (1), 4296, 2019 | 21 | 2019 |
Loss of chloride channel 6 (CLC-6) affects vascular smooth muscle contractility and arterial stiffness via alterations to Golgi calcium stores CA Klemens, EG Chulkov, J Wu, MA Hye Khan, V Levchenko, MJ Flister, ... Hypertension 77 (2), 582-593, 2021 | 13 | 2021 |
Knockout of the circadian clock protein PER1 (Period1) exacerbates hypertension and increases kidney injury in dahl salt-sensitive rats A Zietara, DR Spires, A Juffre, HM Costello, GR Crislip, LG Douma, ... Hypertension 79 (11), 2519-2529, 2022 | 12 | 2022 |
Crosstalk between epithelial sodium channels (ENaC) and basolateral potassium channels (Kir4.1/Kir5.1) in the cortical collecting duct E Isaeva, R Bohovyk, M Fedoriuk, A Shalygin, CA Klemens, A Zietara, ... British journal of pharmacology 179 (12), 2953-2968, 2022 | 10 | 2022 |
Characterization of purinergic receptor 2 signaling in podocytes from diabetic kidneys O Palygin, CA Klemens, E Isaeva, V Levchenko, DR Spires, ... Iscience 24 (6), 2021 | 10 | 2021 |
Sexual dimorphism in the progression of type 2 diabetic kidney disease in T2DN rats DR Spires, O Palygin, V Levchenko, E Isaeva, CA Klemens, S Khedr, ... Physiological Genomics 53 (6), 223-234, 2021 | 10 | 2021 |