Formation of an unfolding intermediate state of soluble chloride intracellular channel protein CLIC1 at acidic pH S Fanucchi, RJ Adamson, HW Dirr Biochemistry 47 (44), 11674-11681, 2008 | 68 | 2008 |
Structural dynamics of soluble chloride intracellular channel protein CLIC1 examined by amide hydrogen− deuterium exchange mass spectrometry SH Stoychev, C Nathaniel, S Fanucchi, M Brock, S Li, K Asmus, ... Biochemistry 48 (35), 8413-8421, 2009 | 55 | 2009 |
Structural insights into the South African HIV-1 subtype C protease: impact of hinge region dynamics and flap flexibility in drug resistance P Naicker, I Achilonu, S Fanucchi, M Fernandes, MAA Ibrahim, HW Dirr, ... Journal of Biomolecular Structure and Dynamics 31 (12), 1370-1380, 2013 | 49 | 2013 |
Role of individual histidines in the pH-dependent global stability of human chloride intracellular channel 1 I Achilonu, S Fanucchi, M Cross, M Fernandes, HW Dirr Biochemistry 51 (5), 995-1004, 2012 | 35 | 2012 |
Effect of pH on the Structure and DNA Binding of the FOXP2 Forkhead Domain A Blane, S Fanucchi Biochemistry 54 (25), 4001-4007, 2015 | 26 | 2015 |
A single amino acid in the hinge loop region of the FOXP forkhead domain is significant for dimerisation K Perumal, HW Dirr, S Fanucchi The Protein Journal 34, 111-121, 2015 | 25 | 2015 |
A Lys–Trp cation− π interaction mediates the dimerization and function of the chloride intracellular channel protein 1 transmembrane domain B Peter, AA Polyansky, S Fanucchi, HW Dirr Biochemistry 53 (1), 57-67, 2014 | 25 | 2014 |
Stability of the domain interface contributes towards the catalytic function at the H-site of class alpha glutathione transferase A1-1 D Balchin, S Fanucchi, I Achilonu, RJ Adamson, J Burke, M Fernandes, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (12), 2228-2233, 2010 | 23 | 2010 |
A key evolutionary mutation enhances DNA binding of the FOXP2 forkhead domain G Morris, S Fanucchi Biochemistry 55 (13), 1959-1967, 2016 | 20 | 2016 |
Role of arginine 29 and glutamic acid 81 interactions in the conformational stability of human chloride intracellular channel 1 D Legg-E’Silva, I Achilonu, S Fanucchi, S Stoychev, M Fernandes, ... Biochemistry 51 (40), 7854-7862, 2012 | 17 | 2012 |
The FOXP2 forkhead domain binds to a variety of DNA sequences with different rates and affinities H Webb, O Steeb, A Blane, L Rotherham, S Aron, P Machanick, H Dirr, ... The journal of biochemistry 162 (1), 45-54, 2017 | 15 | 2017 |
Membrane mimetics induce helix formation and oligomerization of the chloride intracellular channel protein 1 transmembrane domain B Peter, NCML Ngubane, S Fanucchi, HW Dirr Biochemistry 52 (16), 2739-2749, 2013 | 15 | 2013 |
Molecular basis of inhibition of Schistosoma japonicum glutathione transferase by ellagic acid: Insights into biophysical and structural studies BO Akumadu, R Pandian, J Olfsen, R Worth, M Thulo, T Mentor, ... Molecular and Biochemical Parasitology 240, 111319, 2020 | 13 | 2020 |
A phosphomimetic study implicates Ser557 in regulation of FOXP2 DNA binding A Blane, HW Dirr, S Fanucchi The protein journal 37, 311-323, 2018 | 10 | 2018 |
The forkhead domain hinge-loop plays a pivotal role in DNA binding and transcriptional activity of FOXP2 G Morris, S Stoychev, P Naicker, HW Dirr, S Fanucchi Biological Chemistry 399 (8), 881-893, 2018 | 10 | 2018 |
The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function I Achilonu, S Gildenhuys, L Fisher, J Burke, S Fanucchi, BT Sewell, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 10 | 2010 |
The influence of various regions of the FOXP2 sequence on its structure and DNA-binding function M Thulo, MA Rabie, N Pahad, HL Donald, AA Blane, CM Perumal, ... Bioscience Reports 41 (1), BSR20202128, 2021 | 9 | 2021 |
A conserved cationic motif enhances membrane binding and insertion of the chloride intracellular channel protein 1 transmembrane domain B Peter, S Fanucchi, HW Dirr European Biophysics Journal 43, 405-414, 2014 | 7 | 2014 |
A conserved interdomain interaction is a determinant of folding cooperativity in the GST fold N Parbhoo, SH Stoychev, S Fanucchi, I Achilonu, RJ Adamson, ... Biochemistry 50 (32), 7067-7075, 2011 | 6 | 2011 |
The unusual architecture of RNA-dependent RNA polymerase (RdRp)’s catalytic chamber provides a potential strategy for combination therapy against COVID-19 K Metwally, NE Abo-Dya, MI Alahmdi, MZ Albalawi, G Yahya, A Aljoundi, ... Molecules 28 (6), 2806, 2023 | 4 | 2023 |