| 3-(4-{[Benzyl(methyl)amino]methyl}phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) Inhibits Both Acetylcholinesterase and Acetylcholinesterase-Induced β … L Piazzi, A Rampa, A Bisi, S Gobbi, F Belluti, A Cavalli, M Bartolini, ... Journal of medicinal chemistry 46 (12), 2279-2282, 2003 | 320 | 2003 |
| Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds L Piazzi, A Cavalli, F Colizzi, F Belluti, M Bartolini, F Mancini, ... Bioorganic & Medicinal Chemistry Letters 18 (1), 423-426, 2008 | 294 | 2008 |
| Design, synthesis and anticancer activities of stilbene-coumarin hybrid compounds: Identification of novel proapoptotic agents F Belluti, G Fontana, L Dal Bo, N Carenini, C Giommarelli, F Zunino Bioorganic & medicinal chemistry 18 (10), 3543-3550, 2010 | 288 | 2010 |
| SAR of 9-amino-1, 2, 3, 4-tetrahydroacridine-based acetylcholinesterase inhibitors: synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analogues M Recanatini, A Cavalli, F Belluti, L Piazzi, A Rampa, A Bisi, S Gobbi, ... Journal of medicinal chemistry 43 (10), 2007-2018, 2000 | 223 | 2000 |
| Potent inhibition of human phosphodiesterase-5 by icariin derivatives M Dell’Agli, GV Galli, E Dal Cero, F Belluti, R Matera, E Zironi, G Pagliuca, ... Journal of Natural Products 71 (9), 1513-1517, 2008 | 191 | 2008 |
| A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17α-hydroxylase/C17 … M Recanatini, A Bisi, A Cavalli, F Belluti, S Gobbi, A Rampa, P Valenti, ... Journal of medicinal chemistry 44 (5), 672-680, 2001 | 179 | 2001 |
| In vitro evaluation of newly developed chalcone analogues in human cancer cells R De Vincenzo, C Ferlini, M Distefano, C Gaggini, A Riva, E Bombardelli, ... Cancer chemotherapy and pharmacology 46, 305-312, 2000 | 137 | 2000 |
| Acetylcholinesterase inhibitors for potential use in Alzheimer's disease: molecular modeling, synthesis and kinetic evaluation of 11H-indeno-[1, 2-b]-quinolin-10-ylamine … A Rampa, A Bisi, F Belluti, S Gobbi, P Valenti, V Andrisano, V Cavrini, ... Bioorganic & medicinal chemistry 8 (3), 497-506, 2000 | 128 | 2000 |
| Versatility of the curcumin scaffold: discovery of potent and balanced dual BACE-1 and GSK-3β inhibitors RMC Di Martino, A De Simone, V Andrisano, P Bisignano, A Bisi, S Gobbi, ... Journal of medicinal chemistry 59 (2), 531-544, 2016 | 127 | 2016 |
| Cholinesterase inhibitors: Xanthostigmine derivatives blocking the acetylcholinesterase-induced β-amyloid aggregation F Belluti, A Rampa, L Piazzi, A Bisi, S Gobbi, M Bartolini, V Andrisano, ... Journal of Medicinal Chemistry 48 (13), 4444-4456, 2005 | 124 | 2005 |
| Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme S Gobbi, A Cavalli, A Rampa, F Belluti, L Piazzi, A Paluszcak, ... Journal of medicinal chemistry 49 (15), 4777-4780, 2006 | 115 | 2006 |
| Extensive SAR and Computational Studies of 3-{4-[(Benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) Derivatives L Piazzi, A Cavalli, F Belluti, A Bisi, S Gobbi, S Rizzo, M Bartolini, ... Journal of medicinal chemistry 50 (17), 4250-4254, 2007 | 105 | 2007 |
| Acetylcholinesterase Inhibitors: SAR and Kinetic Studies on ω-[N-Methyl-N-(3-alkylcarbamoyloxyphenyl)methyl]aminoalkoxyaryl Derivatives A Rampa, L Piazzi, F Belluti, S Gobbi, A Bisi, M Bartolini, V Andrisano, ... Journal of Medicinal Chemistry 44 (23), 3810-3820, 2001 | 103 | 2001 |
| Synthesis and biological activity of some rigid analogues of flavone-8-acetic acid P Valenti, A Bisi, A Rampa, F Belluti, S Gobbi, A Zampiron, M Carrara Bioorganic & medicinal chemistry 8 (1), 239-246, 2000 | 103 | 2000 |
| Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity A Bisi, C Cappadone, A Rampa, G Farruggia, A Sargenti, F Belluti, ... European journal of medicinal chemistry 127, 577-585, 2017 | 91 | 2017 |
| Imidazolylmethylbenzophenones as highly potent aromatase inhibitors S Gobbi, A Cavalli, M Negri, KE Schewe, F Belluti, L Piazzi, RW Hartmann, ... Journal of medicinal chemistry 50 (15), 3420-3422, 2007 | 89 | 2007 |
| Cholinesterase inhibitors: SAR and enzyme inhibitory activity of 3-[ω-(benzylmethylamino) alkoxy] xanthen-9-ones L Piazzi, F Belluti, A Bisi, S Gobbi, S Rizzo, M Bartolini, V Andrisano, ... Bioorganic & Medicinal Chemistry 15 (1), 575-585, 2007 | 88 | 2007 |
| Small-molecule inhibitors/modulators of amyloid-β peptide aggregation and toxicity for the treatment of Alzheimer's disease: a patent review (2010–2012) F Belluti, A Rampa, S Gobbi, A Bisi Expert opinion on therapeutic patents 23 (5), 581-596, 2013 | 79 | 2013 |
| Fatty acid amide hydrolase (FAAH), acetylcholinesterase (AChE), and butyrylcholinesterase (BuChE): networked targets for the development of carbamates as potential anti … S Montanari, L Scalvini, M Bartolini, F Belluti, S Gobbi, V Andrisano, ... Journal of Medicinal Chemistry 59 (13), 6387-6406, 2016 | 77 | 2016 |
| Identification of chalcone-based antileishmanial agents targeting trypanothione reductase M Ortalli, A Ilari, G Colotti, I De Ionna, T Battista, A Bisi, S Gobbi, A Rampa, ... European journal of medicinal chemistry 152, 527-541, 2018 | 76 | 2018 |
