关注
Daryl L. Richie
Daryl L. Richie
Novartis Institues of BioMedical Research
在 novartis.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
A Role for the Unfolded Protein Response (UPR) in Virulence and Antifungal Susceptibility in Aspergillus fumigatus
DL Richie, L Hartl, V Aimanianda, MS Winters, KK Fuller, MD Miley, ...
PLoS pathogens 5 (1), e1000258, 2009
1862009
Unexpected Link between Metal Ion Deficiency and Autophagy in Aspergillus fumigatus
DL Richie, KK Fuller, J Fortwendel, MD Miley, JW McCarthy, ...
Eukaryotic cell 6 (12), 2437-2447, 2007
1392007
HacA-Independent Functions of the ER Stress Sensor IreA Synergize with the Canonical UPR to Influence Virulence Traits in Aspergillus fumigatus
X Feng, K Krishnan, DL Richie, V Aimanianda, L Hartl, N Grahl, ...
PLoS pathogens 7 (10), e1002330, 2011
1172011
The Aspergillus fumigatus metacaspases CasA and CasB facilitate growth under conditions of endoplasmic reticulum stress
DL Richie, MD Miley, R Bhabhra, GD Robson, JC Rhodes, DS Askew
Molecular microbiology 63 (2), 591-604, 2007
1072007
Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid …
J Bojkovic, DL Richie, DA Six, CM Rath, WS Sawyer, Q Hu, CR Dean
Journal of bacteriology 198 (4), 731-741, 2016
812016
Divergent Protein Kinase A isoforms co‐ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus
KK Fuller, DL Richie, X Feng, K Krishnan, TJ Stephens, ...
Molecular microbiology 79 (4), 1045-1062, 2011
702011
Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents
DL Richie, KV Thompson, C Studer, VC Prindle, T Aust, R Riedl, ...
Antimicrobial agents and chemotherapy 57 (5), 2272-2280, 2013
542013
The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation …
DL Richie, X Feng, L Hartl, V Aimanianda, K Krishnan, ...
Virulence 2 (1), 12-21, 2011
49*2011
An integrated approach for identification and target validation of antifungal compounds active against Erg11p
D Hoepfner, S Karkare, SB Helliwell, M Pfeifer, M Trunzer, ...
Antimicrobial agents and chemotherapy 56 (8), 4233-4240, 2012
322012
Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606
DL Richie, KT Takeoka, J Bojkovic, LE Metzger IV, CM Rath, WS Sawyer, ...
PloS one 11 (8), e0160918, 2016
312016
Synthesis of ciprofloxacin dimers for evaluation of bacterial permeability in atypical chemical space
AG Ross, BM Benton, D Chin, G De Pascale, J Fuller, JA Leeds, F Reck, ...
Bioorganic & medicinal chemistry letters 25 (17), 3468-3475, 2015
302015
Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen …
K Krishnan, X Feng, MV Powers-Fletcher, G Bick, DL Richie, LA Woollett, ...
Eukaryotic cell 12 (4), 512-519, 2013
292013
Nonspecific effect of Mycograb on amphotericin B MIC
DL Richie, MA Ghannoum, N Isham, KV Thompson, NS Ryder
Antimicrobial agents and chemotherapy 56 (7), 3963-3964, 2012
292012
Interplay of Klebsiella pneumoniae fabZ and lpxC Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis
M Mostafavi, L Wang, L Xie, KT Takeoka, DL Richie, F Casey, A Ruzin, ...
Msphere 3 (5), 10.1128/msphere. 00508-18, 2018
242018
Topoisomerase inhibitors addressing fluoroquinolone resistance in Gram-negative bacteria
CK Skepper, D Armstrong, CJ Balibar, D Bauer, C Bellamacina, ...
Journal of Medicinal Chemistry 63 (14), 7773-7816, 2020
232020
LpxK is essential for growth of Acinetobacter baumannii ATCC 19606: relationship to toxic accumulation of lipid A pathway intermediates
JR Wei, DL Richie, M Mostafavi, LE Metzger IV, CM Rath, WS Sawyer, ...
MSphere 2 (4), 10.1128/msphere. 00199-17, 2017
21*2017
Autophagy: a role in metal ion homeostasis?
DL Richie, DS Askew
Autophagy 4 (1), 115-117, 2008
192008
Impaired Ribosome Biogenesis Disrupts the Integration between Morphogenesis and Nuclear Duplication during the Germination of Aspergillus fumigatus
R Bhabhra, DL Richie, HS Kim, WC Nierman, J Fortwendel, JP Aris, ...
Eukaryotic Cell 7 (4), 575-583, 2008
162008
Autophagy in the filamentous fungus Aspergillus fumigatus
DL Richie, DS Askew
Methods in enzymology 451, 241-250, 2008
162008
Discovery and optimization of DNA gyrase and topoisomerase IV inhibitors with potent activity against fluoroquinolone-resistant gram-positive bacteria
G Lapointe, CK Skepper, LM Holder, D Armstrong, C Bellamacina, J Blais, ...
Journal of Medicinal Chemistry 64 (9), 6329-6357, 2021
152021
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