Design and synthesis of new potent anticancer benzothiazole amides and ureas featuring pyridylamide moiety and possessing dual B-RafV600E and C-Raf kinase inhibitory activities AK El-Damasy, JH Lee, SH Seo, NC Cho, AN Pae, G Keum European Journal of Medicinal Chemistry 115, 201-216, 2016 | 64 | 2016 |
Synthesis and in vitro antiproliferative activity of C5-benzyl substituted 2-amino-pyrrolo[2,3-d]pyrimidines as potent Hsp90 inhibitors JH Lee, SC Shin, SH Seo, YH Seo, N Jeong, CW Kim, EEK Kim, G Keum Bioorganic & medicinal chemistry letters 27 (2), 237-241, 2017 | 25 | 2017 |
Synthesis and biological evaluation of 1-(isoxazol-5-ylmethylaminoethyl)-4-phenyl tetrahydropyridine and piperidine derivatives as potent T-type calcium channel blockers with … JH Lee, SH Seo, EJ Lim, NC Cho, G Nam, SB Kang, AN Pae, N Jeong, ... European journal of medicinal chemistry 74, 246-257, 2014 | 22 | 2014 |
Novel 5, 6-disubstituted pyrrolo [2, 3-d] pyrimidine derivatives as broad spectrum antiproliferative agents: Synthesis, cell based assays, kinase profile and molecular docking … JH Lee, AK El-Damasy, SH Seo, CG Gadhe, AN Pae, N Jeong, SS Hong, ... Bioorganic & Medicinal Chemistry 26 (21), 5596-5611, 2018 | 18 | 2018 |
Synthesis and in vitro evaluation of the antitubercular and antibacterial activity of novel oxazolidinones bearing octahydrocyclopenta [c] pyrrol-2-yl moieties D Bhattarai, J Lee, SH Seo, G Nam, H Choo, SB Kang, JH Kwak, T Oh, ... Chemical and Pharmaceutical Bulletin 62 (12), 1214-1224, 2014 | 14 | 2014 |
Structural basis for design of new purine-based inhibitors targeting the hydrophobic binding pocket of hsp90 SC Shin, AK El-Damasy, JH Lee, SH Seo, JH Kim, YH Seo, Y Lee, JH Yu, ... International Journal of Molecular Sciences 21 (24), 9377, 2020 | 10 | 2020 |
A novel tropomyosin-related kinase A inhibitor, KK5101 to treat pancreatic cancer Z Fang, B Han, KH Jung, JH Lee, AK El-Damasy, CG Gadhe, SJ Kim, ... Cancer Letters 426, 25-36, 2018 | 8 | 2018 |
Computational insights into the binding of IN17 inhibitors to MELK M Harger, JH Lee, B Walker, JM Taliaferro, R Edupuganti, KN Dalby, ... Journal of molecular modeling 25, 1-10, 2019 | 6 | 2019 |
Overcoming the imatinib-resistant BCR-ABL mutants with new ureidobenzothiazole chemotypes endowed with potent and broad-spectrum anticancer activity AK El-Damasy, H Jin, JW Park, HJ Kim, H Khojah, SH Seo, JH Lee, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2189097, 2023 | 3 | 2023 |
Maternal embryonic leucine zipper kinase is associated with metastasis in triple-negative breast cancer X Xie, GB Chauhan, R Edupuganti, T Kogawa, J Park, M Tacam, AW Tan, ... Cancer research communications 3 (6), 1078-1092, 2023 | 3 | 2023 |
Oxazolidinone derivatives containing new bicyclic group, having antibacterial activity, and method for treating pathogenic bacterial infections using the same GC Keum, EEK Kim, AN Pae, KI Choi, SB Kang, SH Seo, D Bhattaral, ... US Patent 8,507,540, 2013 | 2 | 2013 |
Ruthenium hydroxide D Bhattarai, J Lee, G Keum Encyclopedia of Reagents for Organic Synthesis, 2001 | 2 | 2001 |
Tetrabutylammonium peroxydisulfate J Lee, D Bhattarai, G Keum Encyclopedia of Reagents for Organic Synthesis, 2001 | 1 | 2001 |
Abstract P6-10-08: Evaluation of potent novel second-generation MELK-selective inhibitor in aggressive breast cancers M Mughees, M Tacam, A Tan, H Gonzalez, ES Villodre, B Debeb, ... Cancer Research 83 (5_Supplement), P6-10-08-P6-10-08, 2023 | | 2023 |
Indolinone derivatives as inhibitors of maternal embryonic leucine zipper kinase KN Dalby, R Edupuganti, J Taliaferro, JH Lee US Patent 10,981,896, 2021 | | 2021 |
Oxazolidinone derivatives and composition for preventing or treating hepatitis C containing the same SK Jang, GC Keum, EEK Kim, SB Kang, Y Suyeon, LEE Juhyeon, SG Lee, ... US Patent 9,422,274, 2016 | | 2016 |
μ‐Oxo‐bis[tetrakis(t‐butyl)phthalocyaninatoiron(III)] J Lee, D Bhattarai, G Keum Encyclopedia of Reagents for Organic Synthesis, 2001 | | 2001 |