受强制性开放获取政策约束的文章 - Alan Fersht了解详情
无法在其他位置公开访问的文章：3 篇
The p53 pathway: origins, inactivation in cancer, and emerging therapeutic approaches
AC Joerger, AR Fersht
Annual review of biochemistry 85 (1), 375-404, 2016
强制性开放获取政策： UK Medical Research Council
Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007
NC Synnott, MR Bauer, S Madden, A Murray, R Klinger, N O'Donovan, ...
Cancer letters 414, 99-106, 2018
强制性开放获取政策： Science Foundation Ireland, UK Medical Research Council
A sequential assignment procedure for proteins that have intermediate line widths in MAS NMR spectra: amyloid fibrils of human CA150. WW2
J Becker, N Ferguson, J Flinders, BJ van Rossum, AR Fersht, H Oschkinat
ChemBioChem 9 (12), 1946-1952, 2008
强制性开放获取政策： German Research Foundation
可在其他位置公开访问的文章：36 篇
Targeted rescue of a destabilized mutant of p53 by an in silico screened drug
FM Boeckler, AC Joerger, G Jaggi, TJ Rutherford, DB Veprintsev, ...
Proceedings of the National Academy of Sciences 105 (30), 10360-10365, 2008
强制性开放获取政策： German Research Foundation, Cancer Research UK
A transient and low-populated protein-folding intermediate at atomic resolution
DM Korzhnev, TL Religa, W Banachewicz, AR Fersht, LE Kay
Science 329 (5997), 1312-1316, 2010
强制性开放获取政策： Canadian Institutes of Health Research
A single-molecule characterization of p53 search on DNA
A Tafvizi, F Huang, AR Fersht, LA Mirny, AM van Oijen
Proceedings of the National Academy of Sciences 108 (2), 563-568, 2011
强制性开放获取政策： US National Institutes of Health
Small molecule induced reactivation of mutant p53 in cancer cells
X Liu, R Wilcken, AC Joerger, IS Chuckowree, J Amin, J Spencer, ...
Nucleic acids research 41 (12), 6034-6044, 2013
强制性开放获取政策： UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Tumor suppressor p53 slides on DNA with low friction and high stability
A Tafvizi, F Huang, JS Leith, AR Fersht, LA Mirny, AM Van Oijen
Biophysical journal 95 (1), L01-L03, 2008
强制性开放获取政策： US National Institutes of Health
General structural motifs of amyloid protofilaments
N Ferguson, J Becker, H Tidow, S Tremmel, TD Sharpe, G Krause, ...
Proceedings of the National Academy of Sciences 103 (44), 16248-16253, 2006
强制性开放获取政策： German Research Foundation
Design of a molecular support for cryo-EM structure determination
TG Martin, TAM Bharat, AC Joerger, X Bai, F Praetorius, AR Fersht, ...
Proceedings of the National Academy of Sciences 113 (47), E7456-E7463, 2016
强制性开放获取政策： German Research Foundation, UK Medical Research Council, European Commission
2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells
MR Bauer, AC Joerger, AR Fersht
Proceedings of the National Academy of Sciences 113 (36), E5271-E5280, 2016
强制性开放获取政策： UK Medical Research Council, European Commission
Structures of closed and open conformations of dimeric human ATM
D Baretić, HK Pollard, DI Fisher, CM Johnson, B Santhanam, CM Truman, ...
Science advances 3 (5), e1700933, 2017
强制性开放获取政策： UK Medical Research Council
Multisite aggregation of p53 and implications for drug rescue
GZ Wang, AR Fersht
Proceedings of the National Academy of Sciences 114 (13), E2634-E2643, 2017
强制性开放获取政策： UK Medical Research Council, European Commission
Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA
R Melero, S Rajagopalan, M Lázaro, AC Joerger, T Brandt, DB Veprintsev, ...
Proceedings of the National Academy of Sciences 108 (2), 557-562, 2011
强制性开放获取政策： US National Institutes of Health
Propagation of aggregated p53: Cross-reaction and coaggregation vs. seeding
GZ Wang, AR Fersht
Proceedings of the National Academy of Sciences 112 (8), 2443-2448, 2015
强制性开放获取政策： UK Medical Research Council, European Commission
Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines
MGJ Baud, MR Bauer, L Verduci, FA Dingler, KJ Patel, DH Roy, ...
European journal of medicinal chemistry 152, 101-114, 2018
强制性开放获取政策： German Research Foundation, Cancer Research UK, UK Medical Research Council …
A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C
MR Bauer, RN Jones, RK Tareque, B Springett, FA Dingler, L Verduci, ...
Future Medicinal Chemistry 11 (19), 2491-2504, 2019
强制性开放获取政策： Genome Canada, German Research Foundation, Cancer Research UK, UK …
Harnessing fluorine–sulfur contacts and multipolar interactions for the design of p53 mutant Y220C rescue drugs
MR Bauer, RN Jones, MGJ Baud, R Wilcken, FM Boeckler, AR Fersht, ...
ACS chemical biology 11 (8), 2265-2274, 2016
强制性开放获取政策： UK Medical Research Council, Worldwide Cancer Research, UK, European Commission
Targeting cavity-creating p53 cancer mutations with small-molecule stabilizers: the Y220X paradigm
MR Bauer, A Krämer, G Settanni, RN Jones, X Ni, R Khan Tareque, ...
ACS Chemical Biology 15 (3), 657-668, 2020
强制性开放获取政策： Genome Canada, German Research Foundation, UK Engineering and Physical …
MDMX contains an autoinhibitory sequence element
M Bista, M Petrovich, AR Fersht
Proceedings of the National Academy of Sciences 110 (44), 17814-17819, 2013
强制性开放获取政策： UK Medical Research Council
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