Direct spectroscopic evidence for a high-spin Fe (IV) intermediate in tyrosine hydroxylase BE Eser, EW Barr, PA Frantom, L Saleh, JM Bollinger Jr, C Krebs, ... Journal of the American Chemical Society 129 (37), 11334-11335, 2007 | 229 | 2007 |
Structural and enzymatic analysis of MshA from Corynebacterium glutamicum: substrate-assisted catalysis MW Vetting, PA Frantom, JS Blanchard Journal of Biological Chemistry 283 (23), 15834-15844, 2008 | 151 | 2008 |
Chemoenzymatic synthesis of GDP-l-fucose and the Lewis X glycan derivatives W Wang, T Hu, PA Frantom, T Zheng, B Gerwe, DS Del Amo, S Garret, ... Proceedings of the National Academy of Sciences 106 (38), 16096-16101, 2009 | 136 | 2009 |
Mutations at four active site residues of biotin carboxylase abolish substrate-induced synergism by biotin CZ Blanchard, YM Lee, PA Frantom, GL Waldrop Biochemistry 38 (11), 3393-3400, 1999 | 89 | 1999 |
Structures and mechanisms of the mycothiol biosynthetic enzymes F Fan, MW Vetting, PA Frantom, JS Blanchard Current opinion in chemical biology 13 (4), 451-459, 2009 | 59 | 2009 |
Reduction and oxidation of the active site iron in tyrosine hydroxylase: kinetics and specificity PA Frantom, J Seravalli, SW Ragsdale, PF Fitzpatrick Biochemistry 45 (7), 2372-2379, 2006 | 58 | 2006 |
Mapping of the Allosteric Network in the Regulation of α-Isopropylmalate Synthase from Mycobacterium tuberculosis by the Feedback Inhibitor l-Leucine: Solution … PA Frantom, HM Zhang, MR Emmett, AG Marshall, JS Blanchard Biochemistry 48 (31), 7457-7464, 2009 | 47 | 2009 |
UDP-(5F)-GlcNAc acts as a slow-binding inhibitor of MshA, a retaining glycosyltransferase PA Frantom, JK Coward, JS Blanchard Journal of the American Chemical Society 132 (19), 6626-6627, 2010 | 45 | 2010 |
Uncoupled forms of tyrosine hydroxylase unmask kinetic isotope effects on chemical steps PA Frantom, PF Fitzpatrick Journal of the American Chemical Society 125 (52), 16190-16191, 2003 | 37 | 2003 |
Intrinsic deuterium isotope effects on benzylic hydroxylation by tyrosine hydroxylase PA Frantom, R Pongdee, GA Sulikowski, PF Fitzpatrick Journal of the American Chemical Society 124 (16), 4202-4203, 2002 | 34 | 2002 |
Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues M Blahut, CE Wise, MR Bruno, G Dong, TM Makris, PA Frantom, ... Journal of Biological Chemistry 294 (33), 12444-12458, 2019 | 29 | 2019 |
Structural evidence for dimer-interface-driven regulation of the type II cysteine desulfurase, SufS JA Dunkle, MR Bruno, FW Outten, PA Frantom Biochemistry 58 (6), 687-696, 2018 | 28 | 2018 |
Kinetic Evidence for Interdomain Communication in the Allosteric Regulation of α-Isopropylmalate Synthase from Mycobacterium tuberculosis LPS De Carvalho, PA Frantom, A Argyrou, JS Blanchard Biochemistry 48 (9), 1996-2004, 2009 | 27 | 2009 |
Structural and functional characterization of α-isopropylmalate synthase and citramalate synthase, members of the LeuA dimer superfamily PA Frantom Archives of biochemistry and biophysics 519 (2), 202-209, 2012 | 24 | 2012 |
Mechanistic and Bioinformatic Investigation of a Conserved Active Site Helix in α-Isopropylmalate Synthase from Mycobacterium tuberculosis, a Member of the … AK Casey, MA Hicks, JL Johnson, PC Babbitt, PA Frantom Biochemistry 53 (18), 2915-2925, 2014 | 23 | 2014 |
SufE D74R substitution alters active site loop dynamics to further enhance SufE interaction with the SufS cysteine desulfurase Y Dai, D Kim, G Dong, LS Busenlehner, PA Frantom, FW Outten Biochemistry 54 (31), 4824-4833, 2015 | 19 | 2015 |
Replacing the traditional graduate chemistry literature seminar with a chemical research literacy course VF Scalfani, PA Frantom, SA Woski Journal of Chemical Education 93 (3), 482-487, 2016 | 17 | 2016 |
Changes in Protein Dynamics in Escherichia coli SufS Reveal a Possible Conserved Regulatory Mechanism in Type II Cysteine Desulfurase Systems D Kim, H Singh, Y Dai, G Dong, LS Busenlehner, FW Outten, PA Frantom Biochemistry 57 (35), 5210-5217, 2018 | 15 | 2018 |
Improving functional annotation in the DRE-TIM metallolyase superfamily through identification of active site fingerprints G Kumar, JL Johnson, PA Frantom Biochemistry 55 (12), 1863-1872, 2016 | 14 | 2016 |
Evolutionarily distinct versions of the multidomain enzyme α-isopropylmalate synthase share discrete mechanisms of V-type allosteric regulation G Kumar, PA Frantom Biochemistry 53 (29), 4847-4856, 2014 | 14 | 2014 |