Aberrant CpG-island methylation has non-random and tumour-type–specific patterns JF Costello, MC Frühwald, DJ Smiraglia, LJ Rush, GP Robertson, X Gao, ... Nature genetics 24 (2), 132-138, 2000 | 1770 | 2000 |
SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers H Li, L Myeroff, D Smiraglia, MF Romero, TP Pretlow, L Kasturi, ... Proceedings of the National Academy of Sciences 100 (14), 8412-8417, 2003 | 362 | 2003 |
IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data D Wang, L Yan, Q Hu, LE Sucheston, MJ Higgins, CB Ambrosone, ... Bioinformatics 28 (5), 729-730, 2012 | 341 | 2012 |
Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies DJ Smiraglia, LJ Rush, MC Frühwald, Z Dai, WA Held, JF Costello, ... Human molecular genetics 10 (13), 1413-1419, 2001 | 309 | 2001 |
Developmental acquisition of genome-wide DNA methylation occurs prior to meiosis in male germ cells CC Oakes, S La Salle, DJ Smiraglia, B Robaire, JM Trasler Developmental biology 307 (2), 368-379, 2007 | 277 | 2007 |
A novel role for mitochondria in regulating epigenetic modifications in the nucleus D Smiraglia, M Kulawiec, GL Bistulfi, S Ghoshal, KK Singh Cancer biology & therapy 7 (8), 1182-1190, 2008 | 240 | 2008 |
Aging results in hypermethylation of ribosomal DNA in sperm and liver of male rats CC Oakes, DJ Smiraglia, C Plass, JM Trasler, B Robaire Proceedings of the National Academy of Sciences 100 (4), 1775-1780, 2003 | 237 | 2003 |
HLTF gene silencing in human colon cancer HR Moinova, WD Chen, L Shen, D Smiraglia, J Olechnowicz, L Ravi, ... Proceedings of the National Academy of Sciences 99 (7), 4562-4567, 2002 | 222 | 2002 |
A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes Z Dai, WG Zhu, CD Morrison, RM Brena, DJ Smiraglia, A Raval, YZ Wu, ... Human molecular genetics 12 (7), 791-801, 2003 | 203 | 2003 |
Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas SR Rosario, MD Long, HC Affronti, AM Rowsam, KH Eng, DJ Smiraglia Nature communications 9 (1), 5330, 2018 | 199 | 2018 |
Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer LT Smith, M Lin, RM Brena, JC Lang, DE Schuller, GA Otterson, ... Proceedings of the National Academy of Sciences 103 (4), 982-987, 2006 | 190 | 2006 |
Distinct epigenetic phenotypes in seminomatous and nonseminomatous testicular germ cell tumors DJ Smiraglia, J Szymanska, SM Kraggerud, RA Lothe, P Peltomäki, ... Oncogene 21 (24), 3909-3916, 2002 | 184 | 2002 |
A unique configuration of genome-wide DNA methylation patterns in the testis CC Oakes, S La Salle, DJ Smiraglia, B Robaire, JM Trasler Proceedings of the National Academy of Sciences 104 (1), 228-233, 2007 | 179 | 2007 |
Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma KL Bennett, M Karpenko, M Lin, R Claus, K Arab, G Dyckhoff, P Plinkert, ... Cancer research 68 (12), 4494-4499, 2008 | 170 | 2008 |
Methylation of the estrogen receptor-α gene promoter is selectively increased in proliferating human aortic smooth muscle cells AK Ying, HH Hassanain, CM Roos, DJ Smiraglia, JPJ Issa, RE Michler, ... Cardiovascular research 46 (1), 172-179, 2000 | 163 | 2000 |
The genomic impact of DNA CpG methylation on gene expression; relationships in prostate cancer MD Long, DJ Smiraglia, MJ Campbell Biomolecules 7 (1), 15, 2017 | 118 | 2017 |
Restriction landmark genome scanning JF Costello, C Plass, WK Cavenee DNA Methylation Protocols, 53-70, 2002 | 118 | 2002 |
Tissue specific DNA methylation of CpG islands in normal human adult somatic tissues distinguishes neural from non-neural tissues S Ghosh, AJ Yates, MC Frühwald, JC Miecznikowski, C Plass, ... Epigenetics 5 (6), 527-538, 2010 | 113 | 2010 |
The study of aberrant methylation in cancer via restriction landmark genomic scanning DJ Smiraglia, C Plass Oncogene 21 (35), 5414-5426, 2002 | 110 | 2002 |
Global methylation profiling of lung cancer identifies novel methylated genes Z Dai, RR Lakshmanan, WG Zhu, DJ Smiraglia, LJ Rush, MC Frühwald, ... Neoplasia 3 (4), 314-323, 2001 | 110 | 2001 |