MDR1‐P‐Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s Amyloid‐β Peptides—Implications for the Mechanisms of Aβ Clearance at the Blood–Brain Barrier D Kuhnke, G Jedlitschky, M Grube, M Krohn, M Jucker, I Mosyagin, ... Brain Pathology 17 (4), 347-353, 2007 | 294 | 2007 |
Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice M Krohn, C Lange, J Hofrichter, K Scheffler, J Stenzel, J Steffen, ... The Journal of clinical investigation 121 (10), 3924-3931, 2011 | 219 | 2011 |
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells J Wenzel, J Lampe, H Müller-Fielitz, R Schuster, M Zille, K Müller, ... Nature neuroscience 24 (11), 1522-1533, 2021 | 218 | 2021 |
Reduced Alzheimer's disease pathology by St. John's Wort treatment is independent of hyperforin and facilitated by ABCC1 and microglia activation in mice J Hofrichter, M Krohn, T Schumacher, C Lange, B Feistel, B Walbroel, ... Current Alzheimer Research 10 (10), 1057-1069, 2013 | 103 | 2013 |
Alzheimer’s and ABC transporters—new opportunities for diagnostics and treatment J Pahnke, O Langer, M Krohn Neurobiology of disease 72, 54-60, 2014 | 100 | 2014 |
Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes L Möhle, N Israel, K Paarmann, M Krohn, S Pietkiewicz, A Müller, ... Acta neuropathologica communications 4, 1-19, 2016 | 95 | 2016 |
Alzheimer's disease and blood–brain barrier function—Why have anti-β-amyloid therapies failed to prevent dementia progression? J Pahnke, LC Walker, K Scheffler, M Krohn Neuroscience & Biobehavioral Reviews 33 (7), 1099-1108, 2009 | 94 | 2009 |
Mitochondrial DNA polymorphisms specifically modify cerebral β-amyloid proteostasis K Scheffler, M Krohn, T Dunkelmann, J Stenzel, B Miroux, S Ibrahim, ... Acta neuropathologica 124, 199-208, 2012 | 76 | 2012 |
Sideritis spp. extracts enhance memory and learning in Alzheimer’s β-amyloidosis mouse models and aged C57Bl/6 mice J Hofrichter, M Krohn, T Schumacher, C Lange, B Feistel, B Walbroel, ... Journal of alzheimer's disease 53 (3), 967-980, 2016 | 68 | 2016 |
Clinico-pathologic function of cerebral ABC transporters-implications for the pathogenesis of Alzheimer's disease J Pahnke, O Wolkenhauer, M Krohn, LC Walker Current Alzheimer research 5 (4), 396-405, 2008 | 65 | 2008 |
ABC transporters B1, C1 and G2 differentially regulate neuroregeneration in mice T Schumacher, M Krohn, J Hofrichter, C Lange, J Stenzel, J Steffen, ... PloS one 7 (4), e35613, 2012 | 57 | 2012 |
Revisiting rodent models: Octodon degus as Alzheimer’s disease model? J Steffen, M Krohn, K Paarmann, C Schwitlick, T Brüning, R Marreiros, ... Acta neuropathologica communications 4, 1-11, 2016 | 54 | 2016 |
Accumulation of murine amyloid-β mimics early Alzheimer’s disease M Krohn, A Bracke, Y Avchalumov, T Schumacher, J Hofrichter, ... Brain 138 (8), 2370-2382, 2015 | 49 | 2015 |
Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary HG Bernstein, G Hölzl, H Dobrowolny, J Hildebrandt, K Trübner, M Krohn, ... Mechanisms of ageing and development 141, 12-21, 2014 | 49 | 2014 |
Determination of spatial and temporal distribution of microglia by 230nm-high-resolution, high-throughput automated analysis reveals different amyloid plaque populations in an … K Scheffler, J Stenzel, M Krohn, C Lange, J Hofrichter, T Schumacher, ... Current Alzheimer research 8 (7), 781-788, 2011 | 43 | 2011 |
Automated detection of β-amyloid-related cortical and subcortical signal changes in a transgenic model of Alzheimer’s disease using high-field MRI SJ Teipel, E Kaza, S Hadlich, A Bauer, T Brüning, AS Plath, M Krohn, ... Journal of Alzheimer's disease: JAD 23 (2), 221, 2011 | 43 | 2011 |
ABCA7 downregulation modifies cellular cholesterol homeostasis and decreases amyloid-β peptide efflux in an in vitro model of the blood-brain barrier Y Lamartinière, MC Boucau, L Dehouck, M Krohn, J Pahnke, P Candela, ... Journal of Alzheimer's Disease 64 (4), 1195-1211, 2018 | 42 | 2018 |
Impaired mitochondrial energy production and ABC transporter function—a crucial interconnection in dementing proteopathies of the brain J Pahnke, C Fröhlich, M Krohn, T Schumacher, K Paarmann Mechanisms of ageing and development 134 (10), 506-515, 2013 | 41 | 2013 |
Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice J Steffen, M Krohn, C Schwitlick, T Brüning, K Paarmann, CU Pietrzik, ... Acta neuropathologica communications 5, 1-9, 2017 | 32 | 2017 |
Cerebral ABC transporter-common mechanisms may modulate neurodegenerative diseases and depression in elderly subjects J Pahnke, C Fröhlich, K Paarmann, M Krohn, N Bogdanovic, D Årsland, ... Archives of Medical Research 45 (8), 738-743, 2014 | 30 | 2014 |