Calibration-free electrochemical biosensors supporting accurate molecular measurements directly in undiluted whole blood H Li, P Dauphin-Ducharme, G Ortega, KW Plaxco Journal of the American Chemical Society 139 (32), 11207-11213, 2017 | 179 | 2017 |
Subsecond-resolved molecular measurements in the living body using chronoamperometrically interrogated aptamer-based sensors N Arroyo-Currás, P Dauphin-Ducharme, G Ortega, KL Ploense, TE Kippin, ... ACS sensors 3 (2), 360-366, 2018 | 115 | 2018 |
Calibration-free measurement of phenylalanine levels in the blood using an electrochemical aptamer-based sensor suitable for point-of-care applications A Idili, C Parolo, G Ortega, KW Plaxco ACS sensors 4 (12), 3227-3233, 2019 | 84 | 2019 |
Real-time monitoring of a protein biomarker C Parolo, A Idili, G Ortega, A Csordas, A Hsu, N Arroyo-Currás, Q Yang, ... ACS sensors 5 (7), 1877-1881, 2020 | 78 | 2020 |
High-precision control of plasma drug levels using feedback-controlled dosing N Arroyo-Currás, G Ortega, DA Copp, KL Ploense, ZA Plaxco, TE Kippin, ... ACS pharmacology & translational science 1 (2), 110-118, 2018 | 73 | 2018 |
Halophilic enzyme activation induced by salts G Ortega, A Laín, X Tadeo, B López-Méndez, D Castano, O Millet Scientific reports 1 (1), 6, 2011 | 72 | 2011 |
Elucidating the mechanisms underlying the signal drift of electrochemical aptamer-based sensors in whole blood KK Leung, AM Downs, G Ortega, M Kurnik, KW Plaxco ACS sensors 6 (9), 3340-3347, 2021 | 70 | 2021 |
Simulation-based approach to determining electron transfer rates using square-wave voltammetry P Dauphin-Ducharme, N Arroyo-Currás, M Kurnik, G Ortega, H Li, ... Langmuir 33 (18), 4407-4413, 2017 | 67 | 2017 |
Repurposing ciclopirox as a pharmacological chaperone in a model of congenital erythropoietic porphyria P Urquiza, A Laín, A Sanz-Parra, J Moreno, G Bernardo-Seisdedos, ... Science translational medicine 10 (459), eaat7467, 2018 | 57 | 2018 |
Halophilic protein adaptation results from synergistic residue-ion interactions in the folded and unfolded states G Ortega, T Diercks, O Millet Chemistry & biology 22 (12), 1597-1607, 2015 | 53 | 2015 |
Hydration dynamics of a halophilic protein in folded and unfolded states J Qvist, G Ortega, X Tadeo, O Millet, B Halle The Journal of Physical Chemistry B 116 (10), 3436-3444, 2012 | 51 | 2012 |
Carbohydrate affinity for the glucose–galactose binding protein is regulated by allosteric domain motions G Ortega, D Castaño, T Diercks, O Millet Journal of the American Chemical Society 134 (48), 19869-19876, 2012 | 46 | 2012 |
Open source software for the real-time control, processing, and visualization of high-volume electrochemical data SD Curtis, KL Ploense, M Kurnik, G Ortega, C Parolo, TE Kippin, ... Analytical chemistry 91 (19), 12321-12328, 2019 | 42 | 2019 |
A plug, print & play inkjet printing and impedance-based biosensing technology operating through a smartphone for clinical diagnostics G Rosati, M Urban, L Zhao, Q Yang, CCC e Silva, S Bonaldo, C Parolo, ... Biosensors and Bioelectronics 196, 113737, 2022 | 41 | 2022 |
Uroporphyrinogen III synthase mutations related to congenital erythropoietic porphyria identify a key helix for protein stability A Fortian, D Castaño, G Ortega, A Laín, M Pons, O Millet Biochemistry 48 (2), 454-461, 2009 | 39 | 2009 |
Chain dynamics limit electron transfer from electrode-bound, single-stranded oligonucleotides P Dauphin-Ducharme, N Arroyo-Currás, R Adhikari, J Somerson, ... The Journal of Physical Chemistry C 122 (37), 21441-21448, 2018 | 37 | 2018 |
Ultra-High-Precision, in-vivo Pharmacokinetic Measurements Highlight the Need for and a Route Toward More Highly Personalized Medicine PA Vieira, CB Shin, N Arroyo-Currás, G Ortega, W Li, AA Keller, ... Frontiers in Molecular Biosciences 6, 69, 2019 | 34 | 2019 |
Unraveling the conformational landscape of ligand binding to glucose/galactose-binding protein by paramagnetic NMR and MD simulations L Unione, G Ortega, A Mallagaray, F Corzana, J Pérez-Castells, ... ACS chemical biology 11 (8), 2149-2157, 2016 | 34 | 2016 |
In Vitro Approach To Identify Key Amino Acids in Low Susceptibility of Rabbit Prion Protein to Misfolding H Erana, N Fernandez-Borges, SR Elezgarai, C Harrathi, JM Charco, ... Journal of virology 91 (24), 10.1128/jvi. 01543-17, 2017 | 29 | 2017 |
Protein functional dynamics in multiple timescales as studied by NMR spectroscopy G Ortega, M Pons, O Millet Advances in protein chemistry and structural biology 92, 219-251, 2013 | 29 | 2013 |