Selection of resistant bacteria at very low antibiotic concentrations E Gullberg, S Cao, OG Berg, C Ilbäck, L Sandegren, D Hughes, ... PLoS pathogens 7 (7), e1002158, 2011 | 1774 | 2011 |
Selection of a multidrug resistance plasmid by sublethal levels of antibiotics and heavy metals E Gullberg, LM Albrecht, C Karlsson, L Sandegren, DI Andersson MBio 5 (5), 10.1128/mbio. 01918-14, 2014 | 491 | 2014 |
Bacterial gene amplification: implications for the evolution of antibiotic resistance L Sandegren, DI Andersson Nature Reviews Microbiology 7 (8), 578-588, 2009 | 372 | 2009 |
Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli L Sandegren, A Lindqvist, G Kahlmeter, DI Andersson Journal of Antimicrobial Chemotherapy 62 (3), 495-503, 2008 | 229 | 2008 |
Selection of antibiotic resistance at very low antibiotic concentrations L Sandegren Upsala journal of medical sciences 119 (2), 103-107, 2014 | 215 | 2014 |
Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak L Sandegren, M Linkevicius, B Lytsy, Å Melhus, DI Andersson Journal of Antimicrobial Chemotherapy 67 (1), 74-83, 2012 | 186 | 2012 |
The first major extended‐spectrum β‐lactamase outbreak in Scandinavia was caused by clonal spread of a multiresistant Klebsiella pneumoniae producing CTX‐M … B Lytsy, L Sandegren, EVA Tano, E Torell, DI Andersson, Å Melhus Apmis 116 (4), 302-8, 2008 | 167 | 2008 |
Potential of tetracycline resistance proteins to evolve tigecycline resistance M Linkevicius, L Sandegren, DI Andersson Antimicrobial agents and chemotherapy 60 (2), 789-796, 2016 | 139 | 2016 |
Antimicrobial drug–resistant Escherichia coli in wild birds and free-range poultry, Bangladesh B Hasan, L Sandegren, Å Melhus, M Drobni, J Hernandez, J Waldenström, ... Emerging infectious diseases 18 (12), 2055, 2012 | 128 | 2012 |
High fitness costs and instability of gene duplications reduce rates of evolution of new genes by duplication-divergence mechanisms M Adler, M Anjum, OG Berg, DI Andersson, L Sandegren Molecular biology and evolution 31 (6), 1526-1535, 2014 | 107 | 2014 |
Mechanisms and fitness costs of tigecycline resistance in Escherichia coli M Linkevicius, L Sandegren, DI Andersson Journal of antimicrobial chemotherapy 68 (12), 2809-2819, 2013 | 99 | 2013 |
Characterization of ESBL disseminating plasmids A Brolund, L Sandegren Infectious diseases 48 (1), 18-25, 2016 | 95 | 2016 |
Combinations of mutations in envZ, ftsI, mrdA, acrB and acrR can cause high-level carbapenem resistance in Escherichia coli M Adler, M Anjum, DI Andersson, L Sandegren Journal of Antimicrobial Chemotherapy 71 (5), 1188-1198, 2016 | 91 | 2016 |
Frequent emergence of porin-deficient subpopulations with reduced carbapenem susceptibility in ESBL-producing Escherichia coli during exposure to ertapenem in an in vitro … T Tängdén, M Adler, O Cars, L Sandegren, E Löwdin Journal of Antimicrobial Chemotherapy 68 (6), 1319-1326, 2013 | 88 | 2013 |
Direct identification of antibiotic resistance genes on single plasmid molecules using CRISPR/Cas9 in combination with optical DNA mapping V Müller, F Rajer, K Frykholm, LK Nyberg, S Quaderi, J Fritzsche, ... Scientific reports 6 (1), 37938, 2016 | 85 | 2016 |
Influence of acquired β-lactamases on the evolution of spontaneous carbapenem resistance in Escherichia coli M Adler, M Anjum, DI Andersson, L Sandegren Journal of Antimicrobial Chemotherapy 68 (1), 51-59, 2013 | 84 | 2013 |
Time lapse investigation of antibiotic susceptibility using a microfluidic linear gradient 3D culture device Z Hou, Y An, K Hjort, K Hjort, L Sandegren, Z Wu Lab on a Chip 14 (17), 3409-3418, 2014 | 80 | 2014 |
Silver resistance genes are overrepresented among Escherichia coli isolates with CTX-M production S Sütterlin, P Edquist, L Sandegren, M Adler, T Tängdén, M Drobni, ... Applied and environmental microbiology 80 (22), 6863-6869, 2014 | 70 | 2014 |
Plasmidome-Analysis of ESBL-Producing Escherichia coli Using Conventional Typing and High-Throughput Sequencing A Brolund, O Franzén, Ö Melefors, K Tegmark-Wisell, L Sandegren PLoS One 8 (6), e65793, 2013 | 67 | 2013 |
Selection of Orphan Rhs Toxin Expression in Evolved Salmonella enterica Serovar Typhimurium S Koskiniemi, F Garza-Sanchez, L Sandegren, JS Webb, BA Braaten, ... PLoS genetics 10 (3), e1004255, 2014 | 65 | 2014 |