RNA polymerase is poised for activation across the genome GW Muse, DA Gilchrist, S Nechaev, R Shah, JS Parker, SF Grissom, ... Nature genetics 39 (12), 1507-1511, 2007 | 891 | 2007 |
RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo J Zeitlinger, A Stark, M Kellis, JW Hong, S Nechaev, K Adelman, M Levine, ... Nature genetics 39 (12), 1512-1516, 2007 | 885 | 2007 |
Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila S Nechaev, DC Fargo, G dos Santos, L Liu, Y Gao, K Adelman Science 327 (5963), 335-338, 2010 | 480 | 2010 |
Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation S Nechaev, K Adelman Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1809 (1), 34-45, 2011 | 343 | 2011 |
NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly DA Gilchrist, S Nechaev, C Lee, SKB Ghosh, JB Collins, L Li, DS Gilmour, ... Genes & development 22 (14), 1921-1933, 2008 | 342 | 2008 |
Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals T Henriques, DA Gilchrist, S Nechaev, M Bern, GW Muse, A Burkholder, ... Molecular cell 52 (4), 517-528, 2013 | 258 | 2013 |
Bidirectional transcription arises from two distinct hubs of transcription factor binding and active chromatin BS Scruggs, DA Gilchrist, S Nechaev, GW Muse, A Burkholder, DC Fargo, ... Molecular cell 58 (6), 1101-1112, 2015 | 240 | 2015 |
The interface of ς with core RNA polymerase is extensive, conserved, and functionally specialized MM Sharp, CL Chan, CZ Lu, MT Marr, S Nechaev, EW Merritt, ... Genes & development 13 (22), 3015-3026, 1999 | 194 | 1999 |
Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling K Adelman, MA Kennedy, S Nechaev, DA Gilchrist, GW Muse, ... Proceedings of the National Academy of Sciences 106 (43), 18207-18212, 2009 | 179 | 2009 |
Mutations of bacterial RNA polymerase leading to resistance to microcin J25 J Yuzenkova, M Delgado, S Nechaev, D Savalia, V Epshtein, ... Journal of Biological Chemistry 277 (52), 50867-50875, 2002 | 171 | 2002 |
Inhibition of Escherichia coli RNA polymerase by bacteriophage T7 gene 2 protein S Nechaev, K Severinov Journal of molecular biology 289 (4), 815-826, 1999 | 106 | 1999 |
Promoter-proximal Pol II: when stalling speeds things up S Nechaev, K Adelman Cell Cycle 7 (11), 1539-1544, 2008 | 101 | 2008 |
Genome of Xanthomonas oryzae bacteriophage Xp10: an odd T-odd phage J Yuzenkova, S Nechaev, J Berlin, D Rogulja, K Kuznedelov, R Inman, ... Journal of molecular biology 330 (4), 735-748, 2003 | 84 | 2003 |
Bacteriophage-induced modifications of host RNA polymerase S Nechaev, K Severinov Annual Reviews in Microbiology 57 (1), 301-322, 2003 | 83 | 2003 |
Recombinant Thermus aquaticus RNA Polymerase, a New Tool for Structure-Based Analysis of Transcription L Minakhin, S Nechaev, EA Campbell, K Severinov Journal of bacteriology 183 (1), 71-76, 2001 | 64 | 2001 |
The histone deacetylase SIRT6 restrains transcription elongation via promoter-proximal pausing JP Etchegaray, L Zhong, C Li, T Henriques, E Ablondi, T Nakadai, ... Molecular cell 75 (4), 683-699. e7, 2019 | 56 | 2019 |
The elusive object of desire—interactions of bacteriophages and their hosts S Nechaev, K Severinov Current opinion in microbiology 11 (2), 186-193, 2008 | 47 | 2008 |
The role of the T7 Gp2 inhibitor of host RNA polymerase in phage development D Savalia, W Robins, S Nechaev, I Molineux, K Severinov Journal of molecular biology 402 (1), 118-126, 2010 | 42 | 2010 |
Transcriptional Activation of Agrobacterium tumefaciens Virulence Gene Promoters in Escherichia coli Requires the A. tumefaciens rpoA Gene, Encoding the … SM Lohrke, S Nechaev, H Yang, K Severinov, SJ Jin Journal of bacteriology 181 (15), 4533-4539, 1999 | 41 | 1999 |
Dissection of two hallmarks of the open promoter complex by mutation in an RNA polymerase core subunit S Nechaev, M Chlenov, K Severinov Journal of Biological Chemistry 275 (33), 25516-25522, 2000 | 40 | 2000 |