Genome-scale CRISPR-mediated control of gene repression and activation LA Gilbert, MA Horlbeck, B Adamson, JE Villalta, Y Chen, EH Whitehead, ... Cell 159 (3), 647-661, 2014 | 2811 | 2014 |
Perturb-Seq: dissecting molecular circuits with scalable single-cell RNA profiling of pooled genetic screens A Dixit, O Parnas, B Li, J Chen, CP Fulco, L Jerby-Arnon, ND Marjanovic, ... cell 167 (7), 1853-1866. e17, 2016 | 1421 | 2016 |
A multiplexed single-cell CRISPR screening platform enables systematic dissection of the unfolded protein response B Adamson, TM Norman, M Jost, MY Cho, JK Nuñez, Y Chen, JE Villalta, ... Cell 167 (7), 1867-1882. e21, 2016 | 1003 | 2016 |
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation MA Horlbeck, LA Gilbert, JE Villalta, B Adamson, RA Pak, Y Chen, ... elife 5, e19760, 2016 | 744 | 2016 |
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage DM Chou, B Adamson, NE Dephoure, X Tan, AC Nottke, KE Hurov, ... Proceedings of the National Academy of Sciences 107 (43), 18475-18480, 2010 | 615 | 2010 |
Pervasive functional translation of noncanonical human open reading frames J Chen, AD Brunner, JZ Cogan, JK Nuñez, AP Fields, B Adamson, ... Science 367 (6482), 1140-1146, 2020 | 481 | 2020 |
A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response B Adamson, A Smogorzewska, FD Sigoillot, RW King, SJ Elledge Nature cell biology 14 (3), 318-328, 2012 | 471 | 2012 |
Enhanced prime editing systems by manipulating cellular determinants of editing outcomes PJ Chen, JA Hussmann, J Yan, F Knipping, P Ravisankar, PF Chen, ... Cell 184 (22), 5635-5652. e29, 2021 | 452 | 2021 |
Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress A Ciccia, AV Nimonkar, Y Hu, I Hajdu, YJ Achar, L Izhar, SA Petit, ... Molecular cell 47 (3), 396-409, 2012 | 327 | 2012 |
Molecular recording of mammalian embryogenesis MM Chan, ZD Smith, S Grosswendt, H Kretzmer, TM Norman, B Adamson, ... Nature 570 (7759), 77-82, 2019 | 313 | 2019 |
Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing JM Replogle, TM Norman, A Xu, JA Hussmann, J Chen, JZ Cogan, ... Nature biotechnology 38 (8), 954-961, 2020 | 297 | 2020 |
Mapping the genetic landscape of human cells MA Horlbeck, A Xu, M Wang, NK Bennett, CY Park, D Bogdanoff, ... Cell 174 (4), 953-967. e22, 2018 | 262 | 2018 |
A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens FD Sigoillot, S Lyman, JF Huckins, B Adamson, E Chung, B Quattrochi, ... Nature methods 9 (4), 363-366, 2012 | 197 | 2012 |
A systematic analysis of factors localized to damaged chromatin reveals PARP-dependent recruitment of transcription factors L Izhar, B Adamson, A Ciccia, J Lewis, L Pontano-Vaites, Y Leng, ... Cell reports 11 (9), 1486-1500, 2015 | 175 | 2015 |
Efficient C• G-to-G• C base editors developed using CRISPRi screens, target-library analysis, and machine learning LW Koblan, M Arbab, MW Shen, JA Hussmann, AV Anzalone, JL Doman, ... Nature biotechnology 39 (11), 1414-1425, 2021 | 166 | 2021 |
An animal model of antipsychotic-induced weight gain AA Arjona, SX Zhang, B Adamson, RJ Wurtman Behavioural brain research 152 (1), 121-127, 2004 | 157 | 2004 |
A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability BC O'Connell, B Adamson, JR Lydeard, ME Sowa, A Ciccia, ... Molecular cell 40 (4), 645-657, 2010 | 130 | 2010 |
Mapping the genetic landscape of DNA double-strand break repair JA Hussmann, J Ling, P Ravisankar, J Yan, A Cirincione, A Xu, ... Cell 184 (22), 5653-5669, 2021 | 116 | 2021 |
Ribosomal DNA transcription-dependent processes interfere with chromosome segregation BN Tomson, D D'Amours, BS Adamson, L Aragon, A Amon Molecular and cellular biology, 2006 | 45 | 2006 |
Prime editing: precision genome editing by reverse transcription J Yan, A Cirincione, B Adamson Molecular Cell 77 (2), 210-212, 2020 | 37 | 2020 |