Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum … JP Hachem, MQ Man, D Crumrine, Y Uchida, BE Brown, V Rogiers, ... Journal of investigative dermatology 125 (3), 510-520, 2005 | 381 | 2005 |
Epidermal sphingolipids: metabolism, function, and roles in skin disorders WM Holleran, Y Takagi, Y Uchida FEBS letters 580 (23), 5456-5466, 2006 | 340 | 2006 |
A homolog of Drosophila grainy head is essential for epidermal integrity in mice SB Ting, J Caddy, N Hislop, T Wilanowski, A Auden, L Zhao, S Ellis, ... Science 308 (5720), 411-413, 2005 | 316 | 2005 |
Peroxisome proliferator-activated receptor (PPAR)-β/δ stimulates differentiation and lipid accumulation in keratinocytes M Schmuth, CM Haqq, WJ Cairns, JC Holder, S Dorsam, S Chang, P Lau, ... Journal of Investigative Dermatology 122 (4), 971-983, 2004 | 311 | 2004 |
Infection and inflammation induce LDL oxidation in vivo RA Memon, I Staprans, M Noor, WM Holleran, Y Uchida, AH Moser, ... Arteriosclerosis, Thrombosis, and Vascular Biology 20 (6), 1536-1542, 2000 | 299 | 2000 |
Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus … MQ Man, Y Hatano, SH Lee, M Man, S Chang, KR Feingold, DYM Leung, ... Journal of Investigative Dermatology 128 (1), 79-86, 2008 | 291 | 2008 |
Epidermal sphingomyelins are precursors for selected stratum corneum ceramides Y Uchida, M Hara, H Nishio, E Sidransky, S Inoue, F Otsuka, A Suzuki, ... Journal of lipid research 41 (12), 2071-2082, 2000 | 287 | 2000 |
Loss of functional ELOVL4 depletes very long-chain fatty acids (≥ C28) and the unique ω-O-acylceramides in skin leading to neonatal death V Vasireddy, Y Uchida, N Salem Jr, SY Kim, MNA Mandal, GB Reddy, ... Human molecular genetics 16 (5), 471-482, 2007 | 286 | 2007 |
Serine protease signaling of epidermal permeability barrier homeostasis JP Hachem, E Houben, D Crumrine, MQ Man, N Schurer, T Roelandt, ... Journal of investigative dermatology 126 (9), 2074-2086, 2006 | 252 | 2006 |
UVB-induced alterations in permeability barrier function: roles for epidermal hyperproliferation and thymocyte-mediated response A Haratake, Y Uchida, M Schmuth, O Tanno, R Yasuda, JH Epstein, ... Journal of investigative dermatology 108 (5), 769-775, 1997 | 220 | 1997 |
Human epidermal glucosylceramides are major precursors of stratum corneum ceramides S Hamanaka, A Suzuki, M Hara, H Nishio, F Otsuka, Y Uchida Journal of Investigative Dermatology 119 (2), 416-423, 2002 | 216 | 2002 |
Omega-hydroxyceramides are required for corneocyte lipid envelope (CLE) formation and normal epidermal permeability barrier function M Behne, Y Uchida, T Seki, PO de Montellano, PM Elias, WM Holleran Journal of investigative dermatology 114 (1), 185-192, 2000 | 215 | 2000 |
Endotoxin and cytokines increase hepatic sphingolipid biosynthesis and produce lipoproteins enriched in ceramides and sphingomyelin RA Memon, WM Holleran, AH Moser, T Seki, Y Uchida, J Fuller, ... Arteriosclerosis, thrombosis, and vascular biology 18 (8), 1257-1265, 1998 | 210 | 1998 |
Omega-O-acylceramide, a lipid essential for mammalian survival Y Uchida, WM Holleran Journal of dermatological science 51 (2), 77-87, 2008 | 201 | 2008 |
Regulation of cathelicidin antimicrobial peptide expression by an endoplasmic reticulum (ER) stress signaling, vitamin D receptor-independent pathway K Park, PM Elias, Y Oda, D Mackenzie, T Mauro, WM Holleran, Y Uchida Journal of Biological Chemistry 286 (39), 34121-34130, 2011 | 186 | 2011 |
Formation and functions of the corneocyte lipid envelope (CLE) PM Elias, R Gruber, D Crumrine, G Menon, ML Williams, JS Wakefield, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 183 | 2014 |
EPR studies of interstitial Ni centers in synthetic diamond crystals J Isoya, H Kanda, Y Uchida Physical Review B 42 (16), 9843, 1990 | 177 | 1990 |
Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid … MQ Man, EH Choi, M Schmuth, D Crumrine, Y Uchida, PM Elias, ... Journal of Investigative Dermatology 126 (2), 386-392, 2006 | 163 | 2006 |
Structural and biochemical basis for the UVB‐induced alterations in epidermal barrier function WM Holleran, Y Uchida, L Halkier‐Sorensen, A Haratake, M Hara, ... Photodermatology, photoimmunology & photomedicine 13 (4), 117-128, 1997 | 163 | 1997 |
Forced convective heat transfer in a curved channel with a square cross section Y Mori, Y Uchida, T Ukon International Journal of Heat and Mass Transfer 14 (11), 1787-1805, 1971 | 162 | 1971 |