Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification A Moretti, L Caron, A Nakano, JT Lam, A Bernshausen, Y Chen, Y Qyang, ... Cell 127 (6), 1151-1165, 2006 | 1245 | 2006 |
Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages L Bu, X Jiang, S Martin-Puig, L Caron, S Zhu, Y Shao, DJ Roberts, ... Nature 460 (7251), 113-117, 2009 | 664 | 2009 |
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/β-catenin pathway Y Qyang, S Martin-Puig, M Chiravuri, S Chen, H Xu, L Bu, X Jiang, L Lin, ... Cell stem cell 1 (2), 165-179, 2007 | 393 | 2007 |
Lives of a heart cell: tracing the origins of cardiac progenitors S Martin-Puig, Z Wang, KR Chien Cell stem cell 2 (4), 320-331, 2008 | 228 | 2008 |
The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen L del Peso, MC Castellanos, E Temes, S Martín-Puig, Y Cuevas, G Olmos, ... Journal of Biological Chemistry 278 (49), 48690-48695, 2003 | 227 | 2003 |
Evidence for the involvement of diacylglycerol kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tension J Aragonés, DR Jones, S Martın, MA San Juan, A Alfranca, F Vidal, ... Journal of Biological Chemistry 276 (13), 10548-10555, 2001 | 133 | 2001 |
Myocardial VHL-HIF signaling controls an embryonic metabolic switch essential for cardiac maturation I Menendez-Montes, B Escobar, B Palacios, MJ Gómez, ... Developmental cell 39 (6), 724-739, 2016 | 124 | 2016 |
Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-γ production through the HIF-1α transcription factor B Acosta-Iborra, A Elorza, IM Olazabal, NB Martín-Cofreces, S Martin-Puig, ... The Journal of Immunology 182 (5), 3155-3164, 2009 | 117 | 2009 |
Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase E Temes, S Martín-Puig, B Acosta-Iborra, MC Castellanos, ... Journal of Biological Chemistry 280 (25), 24238-24244, 2005 | 67 | 2005 |
Specific oncolytic effect of a new hypoxia-inducible factor-dependent replicative adenovirus on von Hippel-Lindau-defective renal cell carcinomas Y Cuevas, R Hernández-Alcoceba, J Aragones, S Naranjo-Suárez, ... Cancer research 63 (20), 6877-6884, 2003 | 57 | 2003 |
SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α E Mira, L Carmona-Rodríguez, B Pérez-Villamil, J Casas, ... Nature communications 9 (1), 575, 2018 | 50 | 2018 |
Role of diacylglycerol induced by hypoxia in the regulation of HIF-1α activity E Temes, S Martın-Puig, J Aragonés, DR Jones, G Olmos, I Mérida, ... Biochemical and biophysical research communications 315 (1), 44-50, 2004 | 42 | 2004 |
Metabolic reprogramming in the heart and lung in a murine model of pulmonary arterial hypertension JL Izquierdo-Garcia, T Arias, Y Rojas, V Garcia-Ruiz, A Santos, ... Frontiers in Cardiovascular Medicine 5, 110, 2018 | 36 | 2018 |
Von Hippel-Lindau protein is required for optimal alveolar macrophage terminal differentiation, self-renewal, and function HM Izquierdo, P Brandi, MJ Gomez, R Conde-Garrosa, E Priego, ... Cell reports 24 (7), 1738-1746, 2018 | 31 | 2018 |
Novel perspectives on the PHD-HIF oxygen sensing pathway in cardioprotection mediated by IPC and RIPC S Martin-Puig, D Tello, J Aragonés Frontiers in Physiology 6, 137, 2015 | 30 | 2015 |
Heart repair: from natural mechanisms of cardiomyocyte production to the design of new cardiac therapies S Martin‐Puig, V Fuster, M Torres Annals of the New York Academy of Sciences 1254 (1), 71-81, 2012 | 28 | 2012 |
Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms S Martín-Puig, E Temes, G Olmos, DR Jones, J Aragonés, MO Landázuri Journal of Biological Chemistry 279 (10), 9504-9511, 2004 | 15 | 2004 |
Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice I Menendez-Montes, B Escobar, MJ Gomez, T Albendea-Gomez, ... Iscience 24 (2), 2021 | 14 | 2021 |
Methods for the induction of a cell to enter the islet 1+ lineage and a method for the expansion thereof KR Chien, Y Qyang, S Martin-Puig US Patent App. 12/526,447, 2011 | 12 | 2011 |
Embryonic echocardiography for assessment of congenital and functional cardiac defects I Menendez-Montes, M Villalba-Orero, B Escobar, S Martin-Puig STAR protocols 2 (4), 100980, 2021 | 1 | 2021 |