| Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL MK Vartiainen, S Guettler, B Larijani, R Treisman Science 316 (5832), 1749-1752, 2007 | 743 | 2007 |
| Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo V Calleja, D Alcor, M Laguerre, J Park, B Vojnovic, BA Hemmings, ... PLoS biology 5 (4), e95, 2007 | 372 | 2007 |
| Role of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibition V Calleja, M Laguerre, PJ Parker, B Larijani PLoS biology 7 (1), e1000017, 2009 | 311 | 2009 |
| eC-CLEM: flexible multidimensional registration software for correlative microscopies P Paul-Gilloteaux, X Heiligenstein, M Belle, MC Domart, B Larijani, ... Nature methods 14 (2), 102-103, 2017 | 282 | 2017 |
| Identification of a novel phosphonocarboxylate inhibitor of Rab geranylgeranyl transferase that specifically prevents Rab prenylation in osteoclasts and macrophages FP Coxon, MH Helfrich, B Larijani, M Muzylak, JE Dunford, D Marshall, ... Journal of Biological Chemistry 276 (51), 48213-48222, 2001 | 208 | 2001 |
| RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin binding S Guettler, MK Vartiainen, F Miralles, B Larijani, R Treisman Molecular and cellular biology 28 (2), 732-742, 2008 | 198 | 2008 |
| HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer M Gijsen, P King, T Perera, PJ Parker, AL Harris, B Larijani, A Kong PLoS biology 8 (12), e1000563, 2010 | 176 | 2010 |
| Correlative and integrated light and electron microscopy of in-resin GFP fluorescence, used to localise diacylglycerol in mammalian cells CJ Peddie, K Blight, E Wilson, C Melia, J Marrison, R Carzaniga, ... Ultramicroscopy 143, 3-14, 2014 | 133 | 2014 |
| Monitoring conformational changes of proteins in cells by fluorescence lifetime imaging microscopy V Calleja, SM Ameer-Beg, B Vojnovic, R Woscholski, J Downward, ... Biochemical journal 372 (1), 33-40, 2003 | 129 | 2003 |
| Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting N Fili, V Calleja, R Woscholski, PJ Parker, B Larijani Proceedings of the National Academy of Sciences 103 (42), 15473-15478, 2006 | 117 | 2006 |
| PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1α I Eke, U Koch, S Hehlgans, V Sandfort, F Stanchi, D Zips, M Baumann, ... The Journal of clinical investigation 120 (7), 2516-2527, 2010 | 109 | 2010 |
| Phosphatidylinositol metabolism and membrane fusion D Poccia, B Larijani Biochemical Journal 418 (2), 233-246, 2009 | 95 | 2009 |
| Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition H Zhang, AL Cohen, S Krishnakumar, IL Wapnir, S Veeriah, G Deng, ... Breast Cancer Research 16, 1-16, 2014 | 92 | 2014 |
| HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells A Kong, V Calleja, P Leboucher, A Harris, PJ Parker, B Larijani PloS one 3 (8), e2881, 2008 | 91 | 2008 |
| Multiple factors contribute to inefficient prenylation of Rab27a in Rab prenylation diseases B Larijani, AN Hume, AK Tarafder, MC Seabra Journal of Biological Chemistry 278 (47), 46798-46804, 2003 | 86 | 2003 |
| Immunogenomics of colorectal cancer response to checkpoint blockade: analysis of the KEYNOTE 177 trial and validation cohorts M Bortolomeazzi, MR Keddar, L Montorsi, A Acha-Sagredo, L Benedetti, ... Gastroenterology 161 (4), 1179-1193, 2021 | 81 | 2021 |
| Regulation of 3-phosphoinositide–dependent protein kinase 1 activity by homodimerization in live cells TA Masters, V Calleja, DA Armoogum, RJ Marsh, CJ Applebee, ... Science signaling 3 (145), ra78-ra78, 2010 | 76 | 2010 |
| Prognostic value of an activation state marker for epidermal growth factor receptor in tissue microarrays of head and neck cancer A Kong, P Leboucher, R Leek, V Calleja, S Winter, A Harris, PJ Parker, ... Cancer research 66 (5), 2834-2843, 2006 | 73 | 2006 |
| Endomembrane PtdIns(3,4,5)P3 activates the PI3K–Akt pathway N Jethwa, GHC Chung, MG Lete, A Alonso, RD Byrne, V Calleja, ... Journal of cell science 128 (18), 3456-3465, 2015 | 70 | 2015 |
| Acute manipulation of diacylglycerol reveals roles in nuclear envelope assembly & endoplasmic reticulum morphology MC Domart, TMC Hobday, CJ Peddie, GHC Chung, A Wang, K Yeh, ... PloS one 7 (12), e51150, 2012 | 69 | 2012 |
Adrian L HarrisProfessor of Medical Oncology, Oxford University在 oncology.ox.ac.uk 的电子邮件经过验证
