| Recent progress in the battle between oncolytic viruses and tumours KA Parato, D Senger, PAJ Forsyth, JC Bell Nature Reviews Cancer 5 (12), 965-976, 2005 | 709 | 2005 |
| Reovirus as an oncolytic agent against experimental human malignant gliomas ME Wilcox, WQ Yang, D Senger, NB Rewcastle, DG Morris, PMA Brasher, ... Journal of the National Cancer Institute 93 (12), 903-912, 2001 | 284 | 2001 |
| Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures DL Senger, RB Campenot The Journal of cell biology 138 (2), 411-421, 1997 | 229 | 1997 |
| Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens JJP Kelly, O Stechishin, A Chojnacki, X Lun, B Sun, DL Senger, P Forsyth, ... Stem cells 27 (8), 1722-1733, 2009 | 226 | 2009 |
| The p75 neurotrophin receptor is a central regulator of glioma invasion ALM Johnston, X Lun, JJ Rahn, A Liacini, L Wang, MG Hamilton, ... PLoS biology 5 (8), e212, 2007 | 200 | 2007 |
| Myxoma virus is a novel oncolytic virus with significant antitumor activity against experimental human gliomas X Lun, W Yang, T Alain, ZQ Shi, H Muzik, JW Barrett, G McFadden, J Bell, ... Cancer research 65 (21), 9982-9990, 2005 | 194 | 2005 |
| Efficacy of systemically administered oncolytic vaccinia virotherapy for malignant gliomas is enhanced by combination therapy with rapamycin or cyclophosphamide XQ Lun, JH Jang, N Tang, H Deng, R Head, JC Bell, DF Stojdl, CL Nutt, ... Clinical Cancer Research 15 (8), 2777-2788, 2009 | 193 | 2009 |
| Disulfiram when combined with copper enhances the therapeutic effects of temozolomide for the treatment of glioblastoma X Lun, JC Wells, N Grinshtein, JC King, X Hao, NH Dang, X Wang, ... Clinical Cancer Research 22 (15), 3860-3875, 2016 | 184 | 2016 |
| Suppression of Rac activity induces apoptosis of human glioma cells but not normal human astrocytes DL Senger, C Tudan, MC Guiot, IE Mazzoni, G Molenkamp, R LeBlanc, ... Cancer research 62 (7), 2131-2140, 2002 | 137 | 2002 |
| Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma ST Beug, CE Beauregard, C Healy, T Sanda, M St-Jean, J Chabot, ... Nature Communications 8 (1), 14278, 2017 | 131 | 2017 |
| Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression A De Boeck, BY Ahn, C D’Mello, X Lun, SV Menon, MM Alshehri, ... Nature communications 11 (1), 4997, 2020 | 130 | 2020 |
| Single-cell spatial immune landscapes of primary and metastatic brain tumours E Karimi, MW Yu, SM Maritan, LJM Perus, M Rezanejad, M Sorin, ... Nature 614 (7948), 555-563, 2023 | 128 | 2023 |
| Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin XQ Lun, H Zhou, T Alain, B Sun, L Wang, JW Barrett, MM Stanford, ... Cancer research 67 (18), 8818-8827, 2007 | 123 | 2007 |
| Myxoma virus virotherapy for glioma in immunocompetent animal models: optimizing administration routes and synergy with rapamycin XQ Lun, T Alain, FJ Zemp, H Zhou, MM Rahman, MG Hamilton, ... Cancer research 70 (2), 598-608, 2010 | 121 | 2010 |
| Effects of Intravenously Administered Recombinant Vesicular Stomatitis Virus (VSV ΔM51 ) on Multifocal and Invasive Gliomas XQ Lun, DL Senger, T Alain, A Oprea, K Parato, D Stojdl, B Lichty, ... Journal of the National Cancer Institute 98 (21), 1546-1557, 2006 | 115 | 2006 |
| Efficacy and safety/toxicity study of recombinant vaccinia virus JX-594 in two immunocompetent animal models of glioma XQ Lun, J Chan, H Zhou, B Sun, JJP Kelly, OO Stechishin, JC Bell, ... Molecular Therapy 18 (11), 1927-1936, 2010 | 113 | 2010 |
| Dipeptidase-1 is an adhesion receptor for neutrophil recruitment in lungs and liver SR Choudhury, L Babes, JJ Rahn, BY Ahn, KAR Goring, JC King, A Lau, ... Cell 178 (5), 1205-1221. e17, 2019 | 104 | 2019 |
| Proteolytic disassembly is a critical determinant for reovirus oncolysis T Alain, TSY Kim, XQ Lun, A Liacini, LA Schiff, DL Senger, PA Forsyth Molecular Therapy 15 (8), 1512-1521, 2007 | 104 | 2007 |
| Reovirus prolongs survival and reduces the frequency of spinal and leptomeningeal metastases from medulloblastoma WQ Yang, D Senger, H Muzik, ZQ Shi, D Johnson, PMA Brasher, ... Cancer research 63 (12), 3162-3172, 2003 | 103 | 2003 |
| Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates WQ Yang, X Lun, CA Palmer, ME Wilcox, H Muzik, ZQ Shi, R Dyck, ... Clinical cancer research 10 (24), 8561-8576, 2004 | 99 | 2004 |
