What antibiotic exposures are required to suppress the emergence of resistance for gram-negative bacteria? A systematic review CD Sumi, AJ Heffernan, J Lipman, JA Roberts, FB Sime Clinical pharmacokinetics 58, 1407-1443, 2019 | 138 | 2019 |
Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort … AA Udy, JM Dulhunty, JA Roberts, JS Davis, SAR Webb, R Bellomo, ... International journal of antimicrobial agents 49 (5), 624-630, 2017 | 98 | 2017 |
Individualising therapy to minimize bacterial multidrug resistance AJ Heffernan, FB Sime, J Lipman, JA Roberts Drugs 78, 621-641, 2018 | 68 | 2018 |
Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by Gram-negative bacilli: a systematic review AJ Heffernan, FB Sime, J Lipman, J Dhanani, K Andrews, D Ellwood, ... International journal of antimicrobial agents 53 (3), 234-245, 2019 | 54 | 2019 |
Host diagnostic biomarkers of infection in the ICU: where are we and where are we going? AJ Heffernan, KJ Denny Current infectious disease reports 23, 1-11, 2021 | 36 | 2021 |
How to optimize antibiotic pharmacokinetic/pharmacodynamics for Gram-negative infections in critically ill patients AJ Heffernan, FB Sime, FS Taccone, JA Roberts Current Opinion in Infectious Diseases 31 (6), 555-565, 2018 | 31 | 2018 |
The effect of the ABCDE/ABCDEF bundle on delirium, functional outcomes, and quality of life in critically ill patients: A systematic review and meta-analysis K Sosnowski, F Lin, W Chaboyer, K Ranse, A Heffernan, M Mitchell International journal of nursing studies 138, 104410, 2023 | 25 | 2023 |
A personalised approach to antibiotic pharmacokinetics and pharmacodynamics in critically ill patients AJ Heffernan, SMS Lim, J Lipman, JA Roberts Anaesthesia Critical Care & Pain Medicine 40 (6), 100970, 2021 | 24 | 2021 |
Vancomycin population pharmacokinetics for adult patients with sepsis or septic shock: are current dosing regimens sufficient? AJ Heffernan, A Germano, FB Sime, JA Roberts, E Kimura European Journal of Clinical Pharmacology 75, 1219-1226, 2019 | 23 | 2019 |
β-lactam antibiotic versus combined β-lactam antibiotics and single daily dosing regimens of aminoglycosides for treating serious infections: A meta-analysis AJ Heffernan, FB Sime, J Sun, J Lipman, A Kumar, K Andrews, D Ellwood, ... International journal of antimicrobial agents 55 (3), 105839, 2020 | 22 | 2020 |
Prolonged versus intermittent infusion of β-lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models S Dhaese, A Heffernan, D Liu, MH Abdul-Aziz, V Stove, VH Tam, ... Clinical Pharmacokinetics 59, 1237-1250, 2020 | 21 | 2020 |
Comparison of continuous versus intermittent enteral feeding in critically ill patients: a systematic review and meta-analysis AJ Heffernan, C Talekar, M Henain, L Purcell, M Palmer, H White Critical Care 26 (1), 325, 2022 | 19 | 2022 |
Factors affecting bowel preparation adequacy and procedural time M Zad, CN Do, A Heffernan, L Johnston, M Al‐Ansari JGH Open 4 (2), 206-214, 2020 | 18 | 2020 |
A systematic review of intravenous β-hydroxybutyrate use in humans–a promising future therapy? H White, AJ Heffernan, S Worrall, A Grunsfeld, M Thomas Frontiers in Medicine 8, 740374, 2021 | 16 | 2021 |
Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion SAM Dhaese, P Colin, H Willems, A Heffernan, B Gadeyne, S Van Vooren, ... International journal of antimicrobial agents 54 (6), 741-749, 2019 | 16 | 2019 |
Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae CD Sumi, AJ Heffernan, S Naicker, K Islam, K Cottrell, SC Wallis, ... Journal of Antimicrobial Chemotherapy 75 (9), 2633-2640, 2020 | 15 | 2020 |
Association between urine output and mortality in critically ill patients: a machine learning approach AJ Heffernan, S Judge, SM Petrie, R Godahewa, C Bergmeir, D Pilcher, ... Critical care medicine 50 (3), e263-e271, 2022 | 13 | 2022 |
Pharmacodynamics of ceftriaxone for the treatment of methicillin‐susceptible Staphylococcus aureus: is it a viable treatment option? AJ Heffernan, FB Sime, SMS Lim, S Adiraju, SC Wallis, J Lipman, ... International Journal of Antimicrobial Agents 59 (3), 106537, 2022 | 12 | 2022 |
Exposures to e-cigarettes and their refills: calls to Australian Poisons Information Centres, 2009-2016 C Wylie, A Heffernan, JA Brown, R Cairns, AM Lynch, J Robinson Med J Aust 210 (3), 126, 2019 | 12 | 2019 |
Dose optimisation of antibiotics used for meningitis AJ Heffernan, JA Roberts Current Opinion in Infectious Diseases 34 (6), 581-590, 2021 | 11 | 2021 |