| Chronic electronic cigarette exposure in mice induces features of COPD in a nicotine-dependent manner I Garcia-Arcos, P Geraghty, N Baumlin, M Campos, AJ Dabo, B Jundi, ... Thorax 71 (12), 1119-1129, 2016 | 334 | 2016 |
| Antimicrobial proteins and polypeptides in pulmonary innate defence MP Rogan, P Geraghty, CM Greene, SJ O'Neill, CC Taggart, ... Respiratory research 7, 1-11, 2006 | 196 | 2006 |
| Neutrophil elastase up-regulates cathepsin B and matrix metalloprotease-2 expression P Geraghty, MP Rogan, CM Greene, RMM Boxio, T Poiriert, M O’Mahony, ... The Journal of Immunology 178 (9), 5871-5878, 2007 | 145 | 2007 |
| Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway DA Bergin, CM Greene, EE Sterchi, C Kenna, P Geraghty, A Belaaouaj, ... Journal of biological chemistry 283 (46), 31736-31744, 2008 | 121 | 2008 |
| Fibroblast growth factor 23 and Klotho contribute to airway inflammation S Krick, A Grabner, N Baumlin, C Yanucil, S Helton, A Grosche, J Sailland, ... European Respiratory Journal 52 (1), 2018 | 106 | 2018 |
| TLR4 protein contributes to cigarette smoke-induced matrix metalloproteinase-1 (MMP-1) expression in chronic obstructive pulmonary disease P Geraghty, AJ Dabo, J D'Armiento Journal of Biological Chemistry 286 (34), 30211-30218, 2011 | 102 | 2011 |
| Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPD S Yoo, S Takikawa, P Geraghty, C Argmann, J Campbell, L Lin, T Huang, ... PLoS genetics 11 (1), e1004898, 2015 | 100 | 2015 |
| Respiratory syncytial virus infections enhance cigarette smoke induced COPD in mice RF Foronjy, AJ Dabo, CC Taggart, S Weldon, P Geraghty PloS one 9 (2), e90567, 2014 | 83 | 2014 |
| A comparison of the inflammatory and proteolytic effects of dung biomass and cigarette smoke exposure in the lung D Mehra, PM Geraghty, AA Hardigan, R Foronjy PloS one 7 (12), e52889, 2012 | 77 | 2012 |
| The biological effects of double-dose alpha-1 antitrypsin augmentation therapy. A pilot clinical trial MA Campos, P Geraghty, G Holt, E Mendes, PR Newby, S Ma, ... American journal of respiratory and critical care medicine 200 (3), 318-326, 2019 | 76 | 2019 |
| Leukemia inhibitory factor protects the lung during respiratory syncytial viral infection RF Foronjy, AJ Dabo, N Cummins, P Geraghty BMC immunology 15, 1-15, 2014 | 76 | 2014 |
| Induction of the unfolded protein response by cigarette smoke is primarily an activating transcription factor 4-C/EBP homologous protein mediated process P Geraghty, A Wallace, JM D’Armiento International Journal of Chronic Obstructive Pulmonary Disease, 309-319, 2011 | 71 | 2011 |
| Alpha-1-antitrypsin aerosolised augmentation abrogates neutrophil elastase-induced expression of cathepsin B and matrix metalloprotease 2 in vivo and in vitro P Geraghty, MP Rogan, CM Greene, ML Brantly, SJ O’Neill, CC Taggart, ... Thorax 63 (7), 621-626, 2008 | 70 | 2008 |
| Increased matrix metalloproteinase (MMPs) levels do not predict disease severity or progression in emphysema JM D’Armiento, MP Goldklang, AA Hardigan, P Geraghty, MD Roth, ... PloS one 8 (2), e56352, 2013 | 69 | 2013 |
| The Glutathione Peroxidase 1–Protein Tyrosine Phosphatase 1B–Protein Phosphatase 2A Axis. A Key Determinant of Airway Inflammation and Alveolar Destruction P Geraghty, AA Hardigan, AM Wallace, O Mirochnitchenko, J Thankachen, ... American journal of respiratory cell and molecular biology 49 (5), 721-730, 2013 | 66 | 2013 |
| Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD) CW Agudelo, BK Kumley, E Area-Gomez, Y Xu, AJ Dabo, P Geraghty, ... PloS one 15 (2), e0228279, 2020 | 60 | 2020 |
| Secretory leucocyte protease inhibitor inhibits interferon-γ-induced cathepsin S expression P Geraghty, CM Greene, M O'Mahony, SJ O'Neill, CC Taggart, ... Journal of Biological Chemistry 282 (46), 33389-33395, 2007 | 60 | 2007 |
| Protein phosphatase 2A regulates innate immune and proteolytic responses to cigarette smoke exposure in the lung AM Wallace, A Hardigan, P Geraghty, S Salim, A Gaffney, J Thankachen, ... Toxicological Sciences 126 (2), 589-599, 2012 | 59 | 2012 |
| Cathepsin S: investigating an old player in lung disease pathogenesis, comorbidities, and potential therapeutics R Brown, S Nath, A Lora, G Samaha, Z Elgamal, R Kaiser, C Taggart, ... Respiratory Research 21, 1-17, 2020 | 57 | 2020 |
| Klotho inhibits interleukin-8 secretion from cystic fibrosis airway epithelia S Krick, N Baumlin, SP Aller, C Aguiar, A Grabner, J Sailland, E Mendes, ... Scientific reports 7 (1), 14388, 2017 | 53 | 2017 |
