Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail D Brasacchio, J Okabe, C Tikellis, A Balcerczyk, P George, EK Baker, ... Diabetes 58 (5), 1229-1236, 2009 | 608 | 2009 |
NADPH oxidase 1 plays a key role in diabetes mellitus–accelerated atherosclerosis SP Gray, E Di Marco, J Okabe, C Szyndralewiez, F Heitz, AC Montezano, ... Circulation 127 (18), 1888-1902, 2013 | 445 | 2013 |
Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy JC Jha, SP Gray, D Barit, J Okabe, A El-Osta, T Namikoshi, ... Journal of the American Society of Nephrology 25 (6), 1237-1254, 2014 | 380 | 2014 |
Epigenetic phenomena linked to diabetic complications L Pirola, A Balcerczyk, J Okabe, A El-Osta Nature Reviews Endocrinology 6 (12), 665-675, 2010 | 277 | 2010 |
Reactive oxygen species can provide atheroprotection via NOX4-dependent inhibition of inflammation and vascular remodeling SP Gray, E Di Marco, K Kennedy, P Chew, J Okabe, A El-Osta, AC Calkin, ... Arteriosclerosis, thrombosis, and vascular biology 36 (2), 295-307, 2016 | 194 | 2016 |
Distinguishing hyperglycemic changes by Set7 in vascular endothelial cells J Okabe, C Orlowski, A Balcerczyk, C Tikellis, MC Thomas, ME Cooper, ... Circulation research 110 (8), 1067-1076, 2012 | 177 | 2012 |
Analysis of the IGF2/H19 imprinting control region uncovers new genetic defects, including mutations of OCT-binding sequences, in patients with 11p15 fetal … J Demars, ME Shmela, S Rossignol, J Okabe, I Netchine, S Azzi, S Cabrol, ... Human molecular genetics 19 (5), 803-814, 2010 | 149 | 2010 |
NADPH oxidase Nox5 accelerates renal injury in diabetic nephropathy JC Jha, C Banal, J Okabe, SP Gray, T Hettige, BSM Chow, ... Diabetes 66 (10), 2691-2703, 2017 | 145 | 2017 |
The Set7 lysine methyltransferase regulates plasticity in oxidative phosphorylation necessary for trained immunity induced by β-glucan ST Keating, L Groh, CDCC van der Heijden, H Rodriguez, JC Dos Santos, ... Cell Reports 31 (3), 2020 | 104 | 2020 |
Vascular histone deacetylation by pharmacological HDAC inhibition H Rafehi, A Balcerczyk, S Lunke, A Kaspi, M Ziemann, KN Harikrishnan, ... Genome research 24 (8), 1271-1284, 2014 | 91 | 2014 |
Process for producing peroxide-vulcanizable, fluorine-containing elastomer A Naraki, M Abe, S Okamoto, J Okabe US Patent 4,943,622, 1990 | 83 | 1990 |
The primary microRNA-208b interacts with Polycomb-group protein, Ezh2, to regulate gene expression in the heart P Mathiyalagan, J Okabe, L Chang, Y Su, XJ Du, A El-Osta Nucleic acids research 42 (2), 790-803, 2013 | 68 | 2013 |
Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes TC Karagiannis, AJE Lin, K Ververis, L Chang, MM Tang, J Okabe, ... Aging (Albany NY) 2 (10), 659, 2010 | 65 | 2010 |
Iron-catalyzed, directed oxidative arylation of olefins with organozinc and Grignard reagents L Ilies, J Okabe, N Yoshikai, E Nakamura Organic Letters 12 (12), 2838-2840, 2010 | 61 | 2010 |
Process for producing modified acrylic rubber K Saito, E Komiya, J Okabe US Patent 6,380,318, 2002 | 57 | 2002 |
Basic peptides as functional components of non-viral gene transfer vehicles M Nakanishi, A Eguchi, T Akuta, E Nagoshi, S Fujita, J Okabe, T Senda, ... Current Protein and Peptide Science 4 (2), 141-150, 2003 | 56 | 2003 |
Reply to “Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex” KN Harikrishnan, S Pal, M Yarski, EK Baker, MZ Chow, MG De Silva, ... Nature genetics 38 (9), 964-967, 2006 | 44 | 2006 |
Gene transfer vectors based on Sendai virus M Nakanishi, H Mizuguchia, K Ashihara, T Senda, T Akuta, J Okabe, ... Journal of controlled release 54 (1), 61-68, 1998 | 44 | 1998 |
Ubiquitin‐specific protease 2‐69 in macrophages potentially modulates metainflammation H Kitamura, S Kimura, Y Shimamoto, J Okabe, M Ito, T Miyamoto, Y Naoe, ... The FASEB Journal 27 (12), 4940-4953, 2013 | 38 | 2013 |
TRF1 is a critical trans-acting factor required for de novo telomere formation in human cells J Okabe, A Eguchi, A Masago, T Hayakawa, M Nakanishi Human molecular genetics 9 (18), 2639-2650, 2000 | 38 | 2000 |