Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, ... Nature medicine 26 (5), 769-780, 2020 | 664 | 2020 |
The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration YB Hu, EB Dammer, RJ Ren, G Wang Translational neurodegeneration 4, 1-10, 2015 | 647 | 2015 |
Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes*♦ CF Sephton, C Cenik, A Kucukural, EB Dammer, B Cenik, YH Han, ... Journal of biological chemistry 286 (2), 1204-1215, 2011 | 501 | 2011 |
Evidence for brain glucose dysregulation in Alzheimer's disease Y An, VR Varma, S Varma, R Casanova, E Dammer, O Pletnikova, ... Alzheimer's & dementia 14 (3), 318-329, 2018 | 411 | 2018 |
A multi-network approach identifies protein-specific co-expression in asymptomatic and symptomatic Alzheimer’s disease NT Seyfried, EB Dammer, V Swarup, D Nandakumar, DM Duong, L Yin, ... Cell systems 4 (1), 60-72. e4, 2017 | 404 | 2017 |
The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease M Wang, ND Beckmann, P Roussos, E Wang, X Zhou, Q Wang, C Ming, ... Scientific data 5 (1), 1-16, 2018 | 322 | 2018 |
Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease S Rangaraju, EB Dammer, SA Raza, P Rathakrishnan, H Xiao, T Gao, ... Molecular neurodegeneration 13, 1-25, 2018 | 315 | 2018 |
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease B Bai, CM Hales, PC Chen, Y Gozal, EB Dammer, JJ Fritz, X Wang, Q Xia, ... Proceedings of the National Academy of Sciences 110 (41), 16562-16567, 2013 | 305 | 2013 |
The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis F Willmund, M del Alamo, S Pechmann, T Chen, V Albanèse, EB Dammer, ... Cell 152 (1), 196-209, 2013 | 283 | 2013 |
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level ECB Johnson, EK Carter, EB Dammer, DM Duong, ES Gerasimov, Y Liu, ... Nature neuroscience 25 (2), 213-225, 2022 | 258 | 2022 |
Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease L Higginbotham, L Ping, EB Dammer, DM Duong, M Zhou, M Gearing, ... Science advances 6 (43), eaaz9360, 2020 | 222 | 2020 |
Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ... Cell reports 32 (2), 2020 | 214 | 2020 |
Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease EB Dammer, CH Na, P Xu, NT Seyfried, DM Duong, D Cheng, M Gearing, ... Journal of biological chemistry 286 (12), 10457-10465, 2011 | 211 | 2011 |
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer’s disease pathogenesis AP Wingo, Y Liu, ES Gerasimov, J Gockley, BA Logsdon, DM Duong, ... Nature genetics 53 (2), 143-146, 2021 | 197 | 2021 |
Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease ECB Johnson, EB Dammer, DM Duong, L Yin, M Thambisetty, ... Molecular neurodegeneration 13, 1-22, 2018 | 176 | 2018 |
Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age AP Wingo, EB Dammer, MS Breen, BA Logsdon, DM Duong, ... Nature communications 10 (1), 1619, 2019 | 166 | 2019 |
A proteomic network approach across the ALS‐FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain ME Umoh, EB Dammer, J Dai, DM Duong, JJ Lah, AI Levey, M Gearing, ... EMBO molecular medicine 10 (1), 48-62, 2018 | 144 | 2018 |
Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination EB Dammer, C Fallini, YM Gozal, DM Duong, W Rossoll, P Xu, JJ Lah, ... PloS one 7 (6), e38658, 2012 | 133 | 2012 |
Alpha-2 macroglobulin in Alzheimer’s disease: a marker of neuronal injury through the RCAN1 pathway VR Varma, S Varma, Y An, TJ Hohman, S Seddighi, R Casanova, A Beri, ... Molecular psychiatry 22 (1), 13-23, 2017 | 128 | 2017 |
Tau-mediated disruption of the spliceosome triggers cryptic RNA splicing and neurodegeneration in Alzheimer’s disease YC Hsieh, C Guo, HK Yalamanchili, M Abreha, R Al-Ouran, Y Li, ... Cell reports 29 (2), 301-316. e10, 2019 | 125 | 2019 |