Revealing nature’s cellulase diversity: the digestion mechanism of Caldicellulosiruptor bescii CelA R Brunecky, M Alahuhta, Q Xu, BS Donohoe, MF Crowley, IA Kataeva, ... Science 342 (6165), 1513-1516, 2013 | 338 | 2013 |
Engineering enhanced cellobiohydrolase activity LE Taylor, BC Knott, JO Baker, PM Alahuhta, SE Hobdey, JG Linger, ... Nature communications 9 (1), 1186, 2018 | 74 | 2018 |
Structural, mutagenic and in silico studies of xyloglucan fucosylation in Arabidopsis thaliana suggest a water‐mediated mechanism BR Urbanowicz, VS Bharadwaj, M Alahuhta, MJ Peña, VV Lunin, ... The Plant Journal 91 (6), 931-949, 2017 | 65 | 2017 |
Atomic resolution crystallography of a complex of triosephosphate isomerase with a reaction‐intermediate analog: New insight in the proton transfer reaction mechanism M Alahuhta, RK Wierenga Proteins: Structure, Function, and Bioinformatics 78 (8), 1878-1888, 2010 | 60 | 2010 |
Engineering towards a complete heterologous cellulase secretome in Yarrowia lipolytica reveals its potential for consolidated bioprocessing H Wei, W Wang, M Alahuhta, T Vander Wall, JO Baker, LE Taylor, ... Biotechnology for biofuels 7, 1-14, 2014 | 56 | 2014 |
Functional Role of the Conserved Active Site Proline of Triosephosphate Isomerase, MG Casteleijn, M Alahuhta, K Groebel, I El-Sayed, K Augustyns, ... Biochemistry 45 (51), 15483-15494, 2006 | 54 | 2006 |
Sequence, structure, and evolution of cellulases in glycoside hydrolase family 48 LO Sukharnikov, M Alahuhta, R Brunecky, A Upadhyay, ME Himmel, ... Journal of Biological Chemistry 287 (49), 41068-41077, 2012 | 47 | 2012 |
Structure of a Thermobifida fusca lytic polysaccharide monooxygenase and mutagenesis of key residues N Kruer-Zerhusen, M Alahuhta, VV Lunin, ME Himmel, YJ Bomble, ... Biotechnology for biofuels 10, 1-12, 2017 | 43 | 2017 |
Discrete and structurally unique proteins (tāpirins) mediate attachment of extremely thermophilic Caldicellulosiruptor species to cellulose SE Blumer-Schuette, M Alahuhta, JM Conway, LL Lee, JV Zurawski, ... Journal of Biological Chemistry 290 (17), 10645-10656, 2015 | 43 | 2015 |
Cel48A from Thermobifida fusca: Structure and site directed mutagenesis of key residues M Kostylev, M Alahuhta, M Chen, R Brunecky, ME Himmel, VV Lunin, ... Biotechnology and bioengineering 111 (4), 664-673, 2014 | 42 | 2014 |
The unique binding mode of cellulosomal CBM4 from Clostridium thermocellum cellobiohydrolase A M Alahuhta, Q Xu, YJ Bomble, R Brunecky, WS Adney, SY Ding, ... Journal of molecular biology 402 (2), 374-387, 2010 | 42 | 2010 |
Heterologous expression of xylanase enzymes in lipogenic yeast Yarrowia lipolytica W Wang, H Wei, M Alahuhta, X Chen, D Hyman, DK Johnson, M Zhang, ... PLoS One 9 (12), e111443, 2014 | 39 | 2014 |
Molecular Mechanism of Polysaccharide Acetylation by the Arabidopsis Xylan O-acetyltransferase XOAT1 VV Lunin, HT Wang, VS Bharadwaj, M Alahuhta, MJ Peña, JY Yang, ... The Plant Cell 32 (7), 2367-2382, 2020 | 37 | 2020 |
Structure and function of the Clostridium thermocellum cellobiohydrolase A X1-module repeat: enhancement through stabilization of the CbhA complex R Brunecky, M Alahuhta, YJ Bomble, Q Xu, JO Baker, SY Ding, ... Acta Crystallographica Section D: Biological Crystallography 68 (3), 292-299, 2012 | 29 | 2012 |
Target highlights in CASP14: Analysis of models by structure providers LT Alexander, R Lepore, A Kryshtafovych, A Adamopoulos, M Alahuhta, ... Proteins: Structure, Function, and Bioinformatics 89 (12), 1647-1672, 2021 | 27 | 2021 |
Novel Multidomain, Multifunctional Glycoside Hydrolases from Highly Lignocellulolytic Caldicellulosiruptor Species JM Conway, JR Crosby, AP Hren, RT Southerland, LL Lee, VV Lunin, ... AIChE Journal 64 (12), 4218-4228, 2018 | 27 | 2018 |
Structure-based protein engineering efforts with a monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties M Alahuhta, M Salin, MG Casteleijn, C Kemmer, I El-Sayed, K Augustyns, ... Protein Engineering, Design & Selection 21 (4), 257-266, 2008 | 23 | 2008 |
Crystal structure and biochemical characterization of Chlamydomonas FDX2 reveal two residues that, when mutated, partially confer FDX2 the redox potential and … M Boehm, M Alahuhta, DW Mulder, EA Peden, H Long, R Brunecky, ... Photosynthesis research 128, 45-57, 2016 | 22 | 2016 |
Structure of a fibronectin type III-like module from Clostridium thermocellum M Alahuhta, Q Xu, R Brunecky, WS Adney, SY Ding, ME Himmel, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 22 | 2010 |
Comparative Biochemical and Structural Analysis of Novel Cellulose Binding Proteins (Tāpirins) from Extremely Thermophilic Caldicellulosiruptor Species LL Lee, WS Hart, VV Lunin, M Alahuhta, YJ Bomble, ME Himmel, ... Applied and Environmental Microbiology 85 (3), e01983-18, 2019 | 21 | 2019 |