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William Lees
William Lees
Birkbeck, University of London
在 lees.org.uk 的电子邮件经过验证
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引用次数
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Inferred allelic variants of immunoglobulin receptor genes: a system for their evaluation, documentation, and naming
M Ohlin, C Scheepers, M Corcoran, WD Lees, CE Busse, D Bagnara, ...
Frontiers in immunology 10, 441872, 2019
582019
A computational analysis of the antigenic properties of haemagglutinin in influenza A H3N2
WD Lees, DS Moss, AJ Shepherd
Bioinformatics 26 (11), 1403-1408, 2010
562010
Diversity in immunogenomics: the value and the challenge
K Peng, Y Safonova, M Shugay, AB Popejoy, OL Rodriguez, F Breden, ...
Nature methods 18 (6), 588-591, 2021
492021
Benchmarking immunoinformatic tools for the analysis of antibody repertoire sequences
E Smakaj, L Babrak, M Ohlin, M Shugay, B Briney, D Tosoni, C Galli, ...
Bioinformatics 36 (6), 1731-1739, 2020
462020
OGRDB: a reference database of inferred immune receptor genes
W Lees, CE Busse, M Corcoran, M Ohlin, C Scheepers, FA Matsen IV, ...
Nucleic acids research 48 (D1), D964-D970, 2020
392020
Germline immunoglobulin genes: disease susceptibility genes hidden in plain sight?
AM Collins, G Yaari, AJ Shepherd, W Lees, CT Watson
Current Opinion in Systems Biology 24, 100-108, 2020
352020
VDJbase: an adaptive immune receptor genotype and haplotype database
A Omer, O Shemesh, A Peres, P Polak, AJ Shepherd, CT Watson, ...
Nucleic acids research 48 (D1), D1051-D1056, 2020
342020
T cell receptor beta germline variability is revealed by inference from repertoire data
A Omer, A Peres, OL Rodriguez, CT Watson, W Lees, P Polak, AM Collins, ...
Genome medicine 14, 1-19, 2022
292022
sumrep: A Summary Statistic Framework for Immune Receptor Repertoire Comparison and Model Validation
BJ Olson, P Moghimi, CA Schramm, A Obraztsova, D Ralph, ...
Frontiers in immunology 10, 2533, 2019
272019
Flexibility and intrinsic disorder are conserved features of hepatitis C virus E2 glycoprotein
L Stejskal, WD Lees, DS Moss, M Palor, RJ Bingham, AJ Shepherd, ...
PLOS Computational Biology 16 (2), e1007710, 2020
222020
Commentary on Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: relevance in infectious diseases and vaccination studies in human populations
AM Collins, A Peres, MM Corcoran, CT Watson, G Yaari, WD Lees, ...
Genes & Immunity 22 (7), 335-338, 2021
202021
Evaluation of a novel multi-immunogen vaccine strategy for targeting 4E10/10E8 neutralizing epitopes on HIV-1 gp41 membrane proximal external region
S Banerjee, H Shi, M Banasik, H Moon, W Lees, Y Qin, A Harley, ...
Virology 505, 113-126, 2017
192017
Utilities for High‐Throughput Analysis of B‐Cell Clonal Lineages
WD Lees, AJ Shepherd
Journal of immunology research 2015 (1), 323506, 2015
172015
investigating substitutions in antibody–antigen complexes Using Molecular Dynamics: a case study with Broad-spectrum, influenza a antibodies
WD Lees, L Stejskal, DS Moss, AJ Shepherd
Frontiers in Immunology 8, 244887, 2017
152017
N-Linked glycans on influenza A H3N2 hemagglutinin constrain binding of host antibodies, but shielding is limited
K Pentiah, WD Lees, DS Moss, AJ Shepherd
Glycobiology 25 (1), 124-132, 2015
142015
Analysis of antigenically important residues in human influenza A virus in terms of B-cell epitopes
WD Lees, DS Moss, AJ Shepherd
Journal of virology 85 (17), 8548-8555, 2011
142011
A BALB/c IGHV reference set, defined by haplotype analysis of long-read VDJ-c sequences from F1 (BALB/cx C57BL/6) mice
KJL Jackson, JT Kos, W Lees, WS Gibson, ML Smith, A Peres, G Yaari, ...
Frontiers in Immunology 13, 888555, 2022
112022
An entropic safety catch controls hepatitis C virus entry and antibody resistance
L Stejskal, MD Kalemera, CB Lewis, M Palor, L Walker, T Daviter, ...
Elife 11, e71854, 2022
102022
Increased epitope complexity correlated with antibody affinity maturation and a novel binding mode revealed by structures of rabbit antibodies against the third variable loop …
R Pan, Y Qin, M Banasik, W Lees, AJ Shepherd, MW Cho, XP Kong
Journal of virology 92 (7), 10.1128/jvi. 01894-17, 2018
102018
Studying antibody repertoires with next-generation sequencing
WD Lees, AJ Shepherd
Bioinformatics: Volume II: Structure, Function, and Applications, 257-270, 2017
92017
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