| Acetylcholinesterase accelerates assembly of amyloid-β-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme NC Inestrosa, A Alvarez, CA Perez, RD Moreno, M Vicente, C Linker, ... Neuron 16 (4), 881-891, 1996 | 1288 | 1996 |
| Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils GV De Ferrari, MA Chacon, MI Barria, JL Garrido, JA Godoy, G Olivares, ... Molecular psychiatry 8 (2), 195-208, 2003 | 451 | 2003 |
| Stable complexes involving acetylcholinesterase and amyloid-β peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer’s fibrils A Alvarez, R Alarcon, C Opazo, EO Campos, FJ Munoz, FH Calderon, ... Journal of Neuroscience 18 (9), 3213-3223, 1998 | 428 | 1998 |
| Acetylcholinesterase promotes the aggregation of amyloid-β-peptide fragments by forming a complex with the growing fibrils A Alvarez, C Opazo, R Alarcón, J Garrido, NC Inestrosa Journal of molecular biology 272 (3), 348-361, 1997 | 364 | 1997 |
| Inhibition of tau phosphorylating protein kinase cdk5 prevents β-amyloid-induced neuronal death A Alvarez, R Toro, A Cáceres, RB Maccioni FEBS letters 459 (3), 421-426, 1999 | 321 | 1999 |
| Amyloid–cholinesterase interactions: implications for Alzheimer’s disease NC Inestrosa, MC Dinamarca, A Alvarez The FEBS journal 275 (4), 625-632, 2008 | 315 | 2008 |
| Wnt-3a overcomes β-amyloid toxicity in rat hippocampal neurons AR Alvarez, JA Godoy, K Mullendorff, GH Olivares, M Bronfman, ... Experimental cell research 297 (1), 186-196, 2004 | 305 | 2004 |
| Protein kinase C inhibits amyloid β‐peptide neurotoxicity by acting on members of the Wnt pathway JL Garrido, J Godoy, A Alvarez, M Bronfman, NC Inestrosa The FASEB journal 16 (14), 1982-1984, 2002 | 219 | 2002 |
| A cdk5–p35 stable complex is involved in the β-amyloid-induced deregulation of cdk5 activity in hippocampal neurons A Alvarez, JP Munoz, RB Maccioni Experimental cell research 264 (2), 266-274, 2001 | 174 | 2001 |
| STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's β-amyloid deposits GI Cancino, EM Toledo, NR Leal, DE Hernandez, LF Yévenes, ... Brain 131 (9), 2425-2442, 2008 | 172 | 2008 |
| Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann‐Pick type C disease AR Alvarez, A Klein, J Castro, GI Cancino, J Amigo, M Mosqueira, ... The FASEB Journal 22 (10), 3617-3627, 2008 | 165 | 2008 |
| Activation of the neuronal c-Abl tyrosine kinase by amyloid-β-peptide and reactive oxygen species AR Alvarez, PC Sandoval, NR Leal, PU Castro, KS Kosik Neurobiology of disease 17 (2), 326-336, 2004 | 165 | 2004 |
| Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function L Varela-Nallar, CP Grabowski, IE Alfaro, AR Alvarez, NC Inestrosa Neural development 4, 1-15, 2009 | 130 | 2009 |
| c-Abl tyrosine kinase modulates tau pathology and Cdk5 phosphorylation in AD transgenic mice GI Cancino, KP de Arce, PU Castro, EM Toledo, R von Bernhardi, ... Neurobiology of aging 32 (7), 1249-1261, 2011 | 129 | 2011 |
| Oxidative Stress: A Pathogenic Mechanism for Niemann‐Pick Type C Disease MC Vázquez, E Balboa, AR Alvarez, S Zanlungo Oxidative medicine and cellular longevity 2012 (1), 205713, 2012 | 124 | 2012 |
| A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme AE Reyes, DR Perez, A Alvarez, J Garrido, MK Gentry, BP Doctor, ... Biochemical and biophysical research communications 232 (3), 652-655, 1997 | 123 | 1997 |
| Anti–ribosomal P protein autoantibodies from patients with neuropsychiatric lupus impair memory in mice M Bravo‐Zehnder, EM Toledo, F Segovia‐Miranda, FG Serrano, ... Arthritis & rheumatology 67 (1), 204-214, 2015 | 116 | 2015 |
| Wnt signaling involvement in β-amyloid-dependent neurodegeneration NC Inestrosa, GV De Ferrari, JL Garrido, A Alvarez, GH Olivares, MI Barrıa, ... Neurochemistry international 41 (5), 341-344, 2002 | 113 | 2002 |
| Acetylcholinesterase is a senile plaque component that promotes assembly of amyloid beta-peptide into Alzheimer's filaments. NC Inestrosa, A Alvarez, F Calderon Molecular psychiatry 1 (5), 359-361, 1996 | 109 | 1996 |
| EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomers L M. Vargas, N Leal, LD Estrada, A Gonzalez, F Serrano, K Araya, ... PloS one 9 (3), e92309, 2014 | 103 | 2014 |
