Short-Chain Dehydrogenases/Reductases (SDR) H Jörnvall, B Persson, S Krook, Maria, Atrian, R Gonzalez-Duarte, ... Biochemistry 34 (18), 6003-6013, 1995 | 1599 | 1995 |
Structural basis for androgen specificity and oestrogen synthesis in human aromatase D Ghosh, J Griswold, M Erman, W Pangborn Nature 457 (7226), 219-223, 2009 | 656 | 2009 |
Structure of human estrogenic 17β-hydroxysteroid dehydrogenase at 2.20 Å resolution D Ghosh, VZ Pletnev, DW Zhu, Z Wawrzak, WL Duax, W Pangborn, ... Structure 3 (5), 503-513, 1995 | 371 | 1995 |
Three-dimensional structure of holo 3 alpha, 20 beta-hydroxysteroid dehydrogenase: a member of a short-chain dehydrogenase family. D Ghosh, CM Weeks, P Grochulski, WL Duax, M Erman, RL Rimsay, ... Proceedings of the National Academy of Sciences 88 (22), 10064-10068, 1991 | 315 | 1991 |
Structure of the insecticidal bacterial δ-endotoxin Cry3Bb1 of Bacillus thuringiensis N Galitsky, V Cody, A Wojtczak, D Ghosh, JR Luft, W Pangborn, L English Acta Crystallographica Section D: Biological Crystallography 57 (8), 1101-1109, 2001 | 287 | 2001 |
The refined three-dimensional structure of 3α, 20β-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases D Ghosh, Z Wawrzak, CM Weeks, WL Duax, M Erman Structure 2 (7), 629-640, 1994 | 284 | 1994 |
Structure of human estrone sulfatase suggests functional roles of membrane association FG Hernandez-Guzman, T Higashiyama, W Pangborn, Y Osawa, ... Journal of Biological Chemistry 278 (25), 22989-22997, 2003 | 204 | 2003 |
Human peroxiredoxin 1 and 2 are not duplicate proteins: the unique presence of CYS83 in Prx1 underscores the structural and functional differences between Prx1 and Prx2 WS Lee, KS Choi, J Riddell, C Ip, D Ghosh, JH Park, YM Park Journal of Biological Chemistry 282 (30), 22011-22022, 2007 | 199 | 2007 |
Novel aromatase inhibitors by structure-guided design D Ghosh, J Lo, D Morton, D Valette, J Xi, J Griswold, S Hubbell, C Egbuta, ... Journal of medicinal chemistry 55 (19), 8464-8476, 2012 | 197 | 2012 |
Human sulfatases: a structural perspective to catalysis D Ghosh Cellular and Molecular Life Sciences 64 (15), 2013-2022, 2007 | 154 | 2007 |
Structure of the ternary complex of human 17β-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+ MW Sawicki, M Erman, T Puranen, P Vihko, D Ghosh Proceedings of the National Academy of Sciences 96 (3), 840-845, 1999 | 150 | 1999 |
Structure of uncomplexed and linoleate-bound Candida cylindracea cholesterol esterase D Ghosh, Z Wawrzak, VZ Pletnev, N Li, R Kaiser, W Pangborn, H Jörnvall, ... Structure 3 (3), 279-288, 1995 | 142 | 1995 |
Porcine carbonyl reductase: structural basis for a functional monomer in short chain dehydrogenases/reductases D Ghosh, M Sawicki, V Pletnev, M Erman, S Ohno, S Nakajin, WL Duax Journal of Biological Chemistry 276 (21), 18457-18463, 2001 | 138 | 2001 |
X-ray structure of human aromatase reveals an androgen-specific active site D Ghosh, J Griswold, M Erman, W Pangborn The Journal of steroid biochemistry and molecular biology 118 (4-5), 197-202, 2010 | 115 | 2010 |
Steroid dehydrogenase structures, mechanism of action, and disease WL Duax, D Ghosh, V Pletnev Academic Press 58, 121-148, 2000 | 115 | 2000 |
A homozygous missense mutation in the IRBP gene (RBP3) associated with autosomal recessive retinitis pigmentosa AI den Hollander, TL McGee, C Ziviello, S Banfi, TP Dryja, ... Investigative ophthalmology & visual science 50 (4), 1864-1872, 2009 | 112 | 2009 |
Origin of substrate specificity of human and rat 17β-hydroxysteroid dehydrogenase type 1, using chimeric enzymes and site-directed substitutions T Puranen, M Poutanen, D Ghosh, R Vihko, P Vihko Endocrinology 138 (8), 3532-3539, 1997 | 103 | 1997 |
Recent progress in the discovery of next generation inhibitors of aromatase from the structure–function perspective D Ghosh, J Lo, C Egbuta Journal of medicinal chemistry 59 (11), 5131-5148, 2016 | 94 | 2016 |
Structural basis for the functional roles of critical residues in human cytochrome P450 aromatase J Lo, G Di Nardo, J Griswold, C Egbuta, W Jiang, G Gilardi, D Ghosh Biochemistry 52 (34), 5821-5829, 2013 | 94 | 2013 |
Characterization of structural and functional properties of human 17β-hydroxysteroid dehydrogenase type 1 using recombinant enzymes and site-directed mutagenesis T Puranen, M Poutanen, D Ghosh, P Vihko, R Vihko Molecular endocrinology 11 (1), 77-86, 1997 | 92 | 1997 |