NAD+-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease R Cerutti, E Pirinen, C Lamperti, S Marchet, AA Sauve, W Li, V Leoni, ... Cell metabolism 19 (6), 1042-1049, 2014 | 381 | 2014 |
Oxysterols and neurodegenerative diseases I Björkhem, A Cedazo-Minguez, V Leoni, S Meaney Molecular aspects of medicine 30 (3), 171-179, 2009 | 324 | 2009 |
Oxysterols as biomarkers in neurodegenerative diseases V Leoni, C Caccia Chemistry and physics of lipids 164 (6), 515-524, 2011 | 239 | 2011 |
Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes M Valenza, V Leoni, JM Karasinska, L Petricca, J Fan, J Carroll, ... Journal of Neuroscience 30 (32), 10844-10850, 2010 | 174 | 2010 |
Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers V Leoni, T Masterman, P Patel, S Meaney, U Diczfalusy, I Björkhem Journal of lipid research 44 (4), 793-799, 2003 | 173 | 2003 |
Oxysterols and Alzheimer's disease I Björkhem, M Heverin, V Leoni, S Meaney, U Diczfalusy Acta Neurologica Scandinavica 114, 43-49, 2006 | 165 | 2006 |
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease V Leoni, C Mariotti, SJ Tabrizi, M Valenza, EJ Wild, SMD Henley, ... Brain 131 (11), 2851-2859, 2008 | 159 | 2008 |
Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease Z Xiang, M Valenza, L Cui, V Leoni, HK Jeong, E Brilli, J Zhang, Q Peng, ... Journal of Neuroscience 31 (26), 9544-9553, 2011 | 144 | 2011 |
Diagnostic use of cerebral and extracerebral oxysterols V Leoni, T Masterman, FS Mousavi, B Wretlind, LO Wahlund, U Diczfalusy, ... Clinical Chemistry and Laboratory Medicine (CCLM) 42 (2), 186-191, 2004 | 144 | 2004 |
Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis V Leoni, T Masterman, U Diczfalusy, G De Luca, J Hillert, I Björkhem Neuroscience letters 331 (3), 163-166, 2002 | 142 | 2002 |
24S-hydroxycholesterol in plasma: a marker of cholesterol turnover in neurodegenerative diseases V Leoni, C Caccia Biochimie 95 (3), 595-612, 2013 | 134 | 2013 |
Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington’s disease M Valenza, V Leoni, A Tarditi, C Mariotti, I Björkhem, S Di Donato, ... Neurobiology of disease 28 (1), 133-142, 2007 | 132 | 2007 |
Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation M Valenza, JB Carroll, V Leoni, LN Bertram, I Björkhem, RR Singaraja, ... Human molecular genetics 16 (18), 2187-2198, 2007 | 132 | 2007 |
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations V Leoni, L Strittmatter, G Zorzi, F Zibordi, S Dusi, B Garavaglia, P Venco, ... Molecular genetics and metabolism 105 (3), 463-471, 2012 | 131 | 2012 |
The impairment of cholesterol metabolism in Huntington disease V Leoni, C Caccia Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 129 | 2015 |
The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease V Leoni Clinical chemistry and laboratory medicine 49 (3), 375-383, 2011 | 119 | 2011 |
Oxysterols and Parkinson's disease: evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease I Björkhem, A Lövgren-Sandblom, V Leoni, S Meaney, L Brodin, ... Neuroscience Letters 555, 102-105, 2013 | 109 | 2013 |
Genetic connections between neurological disorders and cholesterol metabolism I Björkhem, V Leoni, S Meaney Journal of lipid research 51 (9), 2489-2503, 2010 | 106 | 2010 |
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease A Solomon, V Leoni, M Kivipelto, A Besga, AR Öksengård, P Julin, ... Neuroscience letters 462 (1), 89-93, 2009 | 103 | 2009 |
Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment? V Leoni, M Shafaati, A Salomon, M Kivipelto, I Björkhem, LO Wahlund Neuroscience letters 397 (1-2), 83-87, 2006 | 102 | 2006 |