Mechanisms of neurodegeneration in Huntington’s disease JM Gil, AC Rego European Journal of Neuroscience 27 (11), 2803-2820, 2008 | 593 | 2008 |
Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases AC Rego, CR Oliveira Neurochemical research 28, 1563-1574, 2003 | 590 | 2003 |
Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells MW Ward, AC Rego, BG Frenguelli, DG Nicholls Journal of Neuroscience 20 (19), 7208-7219, 2000 | 392 | 2000 |
Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs T Cunha-Oliveira, AC Rego, CR Oliveira Brain research reviews 58 (1), 192-208, 2008 | 285 | 2008 |
An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease PI Moreira, AI Duarte, MS Santos, AC Rego, CR Oliveira Journal of Alzheimer's Disease 16 (4), 741-761, 2009 | 251 | 2009 |
Dysfunctional synapse in Alzheimer's disease–A focus on NMDA receptors SI Mota, IL Ferreira, AC Rego Neuropharmacology 76, 16-26, 2014 | 245 | 2014 |
Amyloid beta peptide 1–42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures IL Ferreira, LM Bajouco, SI Mota, YP Auberson, CR Oliveira, AC Rego Cell calcium 51 (2), 95-106, 2012 | 215 | 2012 |
Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors JMA Oliveira, S Chen, S Almeida, R Riley, J Gonçalves, CR Oliveira, ... Journal of Neuroscience 26 (43), 11174-11186, 2006 | 210 | 2006 |
Shaping the Nrf2-ARE-related pathways in Alzheimer’s and Parkinson’s diseases L Fão, SI Mota, AC Rego Ageing Research Reviews 54, 100942, 2019 | 199 | 2019 |
Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease SI Mota, RO Costa, IL Ferreira, I Santana, GL Caldeira, C Padovano, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (7 …, 2015 | 189 | 2015 |
Mitochondrialand Endoplasmic ReticulumAssociated Oxidative Stress in Alzheimer′ s Disease: From Pathogenesis to Biomarkers E Ferreiro, I Baldeiras, IL Ferreira, RO Costa, AC Rego, CF Pereira, ... International Journal of Cell Biology 2012 (1), 735206, 2012 | 181 | 2012 |
Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3β signaling pathways and changes in protein expression AI Duarte, P Santos, CR Oliveira, MS Santos, AC Rego Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (6), 994-1002, 2008 | 178 | 2008 |
Antioxidant effect of flavonoids after ascorbate/Fe2+-induced oxidative stress in cultured retinal cells FM Areias, AC Rego, CR Oliveira, RM Seabra Biochemical Pharmacology 62 (1), 111-118, 2001 | 172 | 2001 |
Mitochondrial dysfunction in Huntington’s disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice JMA Oliveira, MB Jekabsons, S Chen, A Lin, AC Rego, J Gonçalves, ... Journal of neurochemistry 101 (1), 241-249, 2007 | 170 | 2007 |
Mitochondrial dysfunction in Huntington’s disease C Carmo, L Naia, C Lopes, AC Rego Polyglutamine disorders, 59-83, 2018 | 164 | 2018 |
Effect of amyloid βpeptide on permeability transition pore: A comparative study PI Moreira, MS Santos, A Moreno, AC Rego, C Oliveira Journal of neuroscience research 69 (2), 257-267, 2002 | 158 | 2002 |
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein R Pinho, I Paiva, KG Jerčić, L Fonseca-Ornelas, E Gerhardt, C Fahlbusch, ... Human molecular genetics 28 (1), 31-50, 2019 | 153 | 2019 |
Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage I Paiva, R Pinho, MA Pavlou, M Hennion, P Wales, AL Schütz, A Rajput, ... Human molecular genetics 26 (12), 2231-2246, 2017 | 145 | 2017 |
Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington’s disease knock-in … M Ribeiro, TR Rosenstock, AM Oliveira, CR Oliveira, AC Rego Free Radical Biology and Medicine 74, 129-144, 2014 | 143 | 2014 |
Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine T Cunha-Oliveira, AC Rego, SM Cardoso, F Borges, RH Swerdlow, ... Brain research 1089 (1), 44-54, 2006 | 143 | 2006 |