Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78 MS Gorbatyuk, T Knox, MM LaVail, OS Gorbatyuk, SM Noorwez, ... Proceedings of the National Academy of Sciences 107 (13), 5961-5966, 2010 | 301 | 2010 |
Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of … T Knox, E Sahakian, D Banik, M Hadley, E Palmer, S Noonepalle, J Kim, ... Scientific reports 9 (1), 6136, 2019 | 153 | 2019 |
Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation KV Woan, M Lienlaf, P Perez-Villaroel, C Lee, F Cheng, T Knox, ... Molecular oncology 9 (7), 1447-1457, 2015 | 151 | 2015 |
Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells F Cheng, M Lienlaf, P Perez-Villarroel, HW Wang, C Lee, K Woan, ... Molecular immunology 60 (1), 44-53, 2014 | 151 | 2014 |
Essential role of HDAC6 in the regulation of PD-L1 in melanoma M Lienlaf, P Perez-Villarroel, T Knox, M Pabon, E Sahakian, J Powers, ... Molecular oncology 10 (5), 735-750, 2016 | 149 | 2016 |
Discovery of a new isoxazole-3-hydroxamate-based histone deacetylase 6 inhibitor SS-208 with antitumor activity in syngeneic melanoma mouse models S Shen, M Hadley, K Ustinova, J Pavlicek, T Knox, S Noonepalle, ... Journal of medicinal chemistry 62 (18), 8557-8577, 2019 | 70 | 2019 |
Synthesis and pharmacological evaluation of selective histone deacetylase 6 inhibitors in melanoma models MT Tavares, S Shen, T Knox, M Hadley, Z Kutil, C Bařinka, A Villagra, ... ACS Medicinal Chemistry Letters 8 (10), 1031-1036, 2017 | 39 | 2017 |
Functional analysis of histone deacetylase 11 (HDAC11) J Chen, E Sahakian, J Powers, M Lienlaf, P Perez-Villarroel, T Knox, ... Histone Deacetylases: Methods and Protocols, 147-165, 2016 | 20 | 2016 |
Expression and function of histone deacetylase 10 (HDAC10) in B cell malignancies J Powers, M Lienlaf, P Perez-Villarroel, S Deng, T Knox, A Villagra, ... Histone Deacetylases: Methods and Protocols, 129-145, 2016 | 17 | 2016 |
A novel FGFR3 splice variant preferentially expressed in african american prostate cancer drives aggressive phenotypes and docetaxel resistance J Olender, BD Wang, T Ching, LX Garmire, K Garofano, Y Ji, T Knox, ... Molecular Cancer Research 17 (10), 2115-2125, 2019 | 14 | 2019 |
Histone deacetylase 6 (HDAC6) as a regulator of immune check-point molecules in chronic lymphocytic leukemia (CLL) JJ Powers, KK Maharaj, E Sahakian, L Xing, P PerezVillarroel, T Knox, ... Blood 124 (21), 3311, 2014 | 13 | 2014 |
Author Correction: Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down … T Knox, E Sahakian, D Banik, M Hadley, E Palmer, S Noonepalle, J Kim, ... Scientific Reports 9 (1), 14824, 2019 | 8 | 2019 |
Reprogramming macrophages with HDAC6 inhibitors for anti-cancer macrophage-based cell therapy SKR Noonepalle, MG Hernandez, CZ Delgado, N Aghdam, N Gajendran, ... Cancer Research 83 (7_Supplement), 900-900, 2023 | 1 | 2023 |
Modulation of lactate in the tumor microenvironment with lactate transporter inhibitor in a melanoma syngeneic mouse model SKR Noonepalle, J Kim, M Hadley, E Palmer, D Banik, T Knox, ... Cancer Research 78 (13_Supplement), 5126-5126, 2018 | 1 | 2018 |
Evaluating HDAC6 as a causal factor in metastatic breast cancer to develop immunotherapy D Banik, M Hadley, J Kim, T Knox, J Nair, A Kozikowski, S Shen, C Vyas, ... Cancer Research 77 (13_Supplement), 4854-4854, 2017 | 1 | 2017 |
Erratum to: Functional Analysis of Histone Deacetylase 11 (HDAC11) J Chen, E Sahakian, J Powers, M Lienlaf, P Perez-Villarroel, T Knox, ... Histone Deacetylases: Methods and Protocols, E1-E1, 2016 | 1 | 2016 |
Histone deacetylase 6 (HDAC6) as a regulator of PD-L1 expression through STAT3 modulation in melanoma M Lienlaf, P Perez-Villarroel, C Lee, F Cheng, J Canales, T Knox, ... Cancer Research 74 (19_Supplement), 4089-4089, 2014 | 1 | 2014 |
Critical Role for Histone Deacetylase 6 (HDAC6) in the Regulation of IL-6, and the JAK/STA3 Signaling Cascade in Macrophages M Lienlaf, P Perez-Villarroel, F Cheng, H Wang, D Marante, S Yoder, ... Blood 120 (21), 1039, 2012 | 1 | 2012 |
Abstract LB-074: Priming the tumor microenvironment with epigenetic modifiers to overcome resistance to immune checkpoint inhibitors TJ Knox, E Sahakian, D Banik, M Hadley, E Palmer, J Kim, S Noonepalle, ... Cancer Research 79 (13_Supplement), LB-074-LB-074, 2019 | | 2019 |
The HDAC6 inhibitor Nexturastat A improves in vivo PD-1 immune blockade T Knox, E Sahakian, D Banik, M Hadley, E Palmer, J Kim, J Powers, ... Cancer Research 78 (13_Supplement), 1703-1703, 2018 | | 2018 |