Type I interferon signals in macrophages and dendritic cells control dengue virus infection: implications for a new mouse model to test dengue vaccines R Züst, YX Toh, I Valdés, D Cerny, J Heinrich, L Hermida, E Marcos, ... Journal of virology 88 (13), 7276-7285, 2014 | 111 | 2014 |
In vitro assembly of nucleocapsid-like particles from purified recombinant capsid protein of dengue-2 virus C López, L Gil, L Lazo, I Menéndez, E Marcos, J Sánchez, I Valdés, ... Archives of virology 154, 695-698, 2009 | 66 | 2009 |
Recombinant nucleocapsid-like particles from dengue-2 virus induce protective CD4+ and CD8+ cells against viral encephalitis in mice L Gil, C Lopez, L Lazo, I Valdés, E Marcos, R Alonso, A Gambe, J Martín, ... International immunology 21 (10), 1175-1183, 2009 | 47 | 2009 |
The protein DIIIC‐2, aggregated with a specific oligodeoxynucleotide and adjuvanted in alum, protects mice and monkeys against DENV‐2 L Gil, E Marcos, A Izquierdo, L Lazo, I Valdés, P Ambala, L Ochola, ... Immunology and cell biology 93 (1), 57-66, 2015 | 43 | 2015 |
Generation and characterization of potential dengue vaccine candidates based on domain III of the envelope protein and the capsid protein of the four serotypes of dengue virus E Suzarte, E Marcos, L Gil, I Valdés, L Lazo, Y Ramos, Y Pérez, V Falcón, ... Archives of virology 159, 1629-1640, 2014 | 39 | 2014 |
Recombinant nucleocapsid-like particles from dengue-2 induce functional serotype-specific cell-mediated immunity in mice L Gil, L Bernardo, A Pavon, A Izquierdo, I Valdes, L Lazo, E Marcos, ... Journal of general virology 93 (6), 1204-1214, 2012 | 35 | 2012 |
Nucleocapsid-like particles of dengue-2 virus enhance the immune response against a recombinant protein of dengue-4 virus L Lazo, L Gil, C Lopez, I Valdes, E Marcos, M Álvarez, A Blanco, ... Archives of virology 155, 1587-1595, 2010 | 35 | 2010 |
Capsid protein: evidences about the partial protective role of neutralizing antibody-independent immunity against dengue in monkeys L Gil, A Izquierdo, L Lazo, I Valdés, P Ambala, L Ochola, E Marcos, ... Virology 456, 70-76, 2014 | 34 | 2014 |
The chimeric protein domain III-capsid of dengue virus serotype 2 (DEN-2) successfully boosts neutralizing antibodies generated in monkeys upon infection with DEN-2 I Valdés, L Gil, Y Romero, J Castro, P Puente, L Lazo, E Marcos, ... Clinical and Vaccine Immunology 18 (3), 455-459, 2011 | 34 | 2011 |
A novel tetravalent formulation combining the four aggregated domain III-capsid proteins from dengue viruses induces a functional immune response in mice and monkeys E Suzarte, L Gil, I Valdés, E Marcos, L Lazo, A Izquierdo, A García, ... International immunology 27 (8), 367-379, 2015 | 33 | 2015 |
A tetravalent formulation based on recombinant nucleocapsid-like particles from dengue viruses induces a functional immune response in mice and monkeys L Gil, K Cobas, L Lazo, E Marcos, L Hernández, E Suzarte, A Izquierdo, ... The Journal of Immunology 197 (9), 3597-3606, 2016 | 32 | 2016 |
Evaluation in mice of the immunogenicity and protective efficacy of a tetravalent subunit vaccine candidate against dengue virus L Lazo, A Izquierdo, E Suzarte, L Gil, I Valdés, E Marcos, M Álvarez, ... Microbiology and immunology 58 (4), 219-226, 2014 | 26 | 2014 |
A tetravalent dengue vaccine containing a mix of domain III-P64k and domain III-capsid proteins induces a protective response in mice A Izquierdo, A García, L Lazo, L Gil, E Marcos, M Alvarez, I Valdés, ... Archives of virology 159, 2597-2604, 2014 | 21 | 2014 |
Purified and highly aggregated chimeric protein DIIIC-2 induces a functional immune response in mice against dengue 2 virus E Marcos, L Gil, L Lazo, A Izquierdo, E Brown, E Suzarte, I Valdés, ... Archives of virology 158, 225-230, 2013 | 20 | 2013 |
The tetravalent formulation of domain III‐capsid proteins recalls memory B‐and T‐cell responses induced in monkeys by an experimental dengue virus infection L Gil, L Lazo, I Valdés, E Suzarte, P Yen, R Ramírez, M Álvarez, LT Dung, ... Clinical & translational immunology 6 (6), e148, 2017 | 18 | 2017 |
Comparative proteomic analysis of growth hormone secretagogue A233 treatment of murine macrophage cells J774A. 2 indicates it has a role in antiviral innate response R Martínez, TN de Villavicencio-Díaz, A Sánchez, Y Ramos, JN Ferro, ... Biochemistry and Biophysics Reports 5, 379-387, 2016 | 14 | 2016 |
A dose-response study in mice of a tetravalent vaccine candidate composed of domain III-capsid proteins from dengue viruses I Valdés, E Marcos, E Suzarte, Y Pérez, E Brown, L Lazo, K Cobas, ... Archives of virology 162, 2247-2256, 2017 | 11 | 2017 |
A heterologous prime-boost strategy for immunization against Dengue virus combining the Tetra DIIIC subunit vaccine candidate with the TV005 live-attenuated tetravalent vaccine I Valdés, A Izquierdo, K Cobas, P Thao, H Anh Duc, H Duc Loc, LT Dung, ... Journal of General Virology 100 (6), 975-984, 2019 | 8 | 2019 |
Could an experimental dengue virus infection fail to induce solid immunity against homologous viral challenge in non-human primates? I Valdés, L Gil, L Lazo, E Marcos, J Martín, E Suzarte, J Castro, Y Romero, ... Archives of virology 161, 465-470, 2016 | 7 | 2016 |
Virus-like particles as nanovaccine candidates G Guillen, JC Aguilar, S Dueñas, L Hermida, E Iglesias, E Penton, ... Advances in Natural Sciences: Nanoscience and Nanotechnology 4 (1), 015005, 2013 | 7 | 2013 |