Human circulating PD-1+ CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses M Locci, C Havenar-Daughton, E Landais, J Wu, MA Kroenke, ... Immunity 39, 758-9, 2013 | 916 | 2013 |
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses MG Alameh, I Tombácz, E Bettini, K Lederer, S Ndeupen, C Sittplangkoon, ... Immunity 54 (12), 2877-2892. e7, 2021 | 488 | 2021 |
Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation MA Kroenke, D Eto, M Locci, M Cho, T Davidson, EK Haddad, S Crotty The Journal of Immunology 188 (8), 3734-3744, 2012 | 411 | 2012 |
SARS-CoV-2 mRNA vaccines foster potent antigen-specific germinal center responses associated with neutralizing antibody generation K Lederer, D Castaño, DG Atria, TH Oguin, S Wang, TB Manzoni, ... Immunity 53 (6), 1281-1295. e5, 2020 | 372 | 2020 |
A single immunization with nucleoside-modified mRNA vaccines elicits strong cellular and humoral immune responses against SARS-CoV-2 in mice D Laczkó, MJ Hogan, SA Toulmin, P Hicks, K Lederer, BT Gaudette, ... Immunity 53 (4), 724-732. e7, 2020 | 362 | 2020 |
SARS-CoV-2 mRNA vaccines: immunological mechanism and beyond E Bettini, M Locci Vaccines 9 (2), 147, 2021 | 275 | 2021 |
A distinct subpopulation of CD25− T-follicular regulatory cells localizes in the germinal centers JB Wing, Y Kitagawa, M Locci, H Hume, C Tay, T Morita, Y Kidani, ... Proceedings of the National Academy of Sciences 114 (31), E6400-E6409, 2017 | 209 | 2017 |
Activin A programs the differentiation of human TFH cells M Locci, JE Wu, F Arumemi, Z Mikulski, C Dahlberg, AT Miller, S Crotty Nature immunology 17 (8), 976-984, 2016 | 195 | 2016 |
The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development R Kageyama, JL Cannons, F Zhao, I Yusuf, C Lao, M Locci, ... Immunity 36 (6), 986-1002, 2012 | 185 | 2012 |
Direct probing of germinal center responses reveals immunological features and bottlenecks for neutralizing antibody responses to HIV Env trimer C Havenar-Daughton, DG Carnathan, AT de la Peña, M Pauthner, ... Cell reports 17 (9), 2195-2209, 2016 | 171 | 2016 |
SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC) AD Proal, MB VanElzakker, S Aleman, K Bach, BP Boribong, M Buggert, ... Nature Immunology 24 (10), 1616-1627, 2023 | 151 | 2023 |
Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals K Lederer, E Bettini, K Parvathaneni, MM Painter, D Agarwal, ... Cell 185 (6), 1008-1024. e15, 2022 | 141 | 2022 |
Evidence for long-term efficacy and safety of gene therapy for Wiskott–Aldrich syndrome in preclinical models F Marangoni, M Bosticardo, S Charrier, E Draghici, M Locci, ... Molecular Therapy 17 (6), 1073-1082, 2009 | 108 | 2009 |
Reversible reprogramming of circulating memory T follicular helper cell function during chronic HIV infection R Cubas, J Van Grevenynghe, S Wills, L Kardava, BH Santich, ... The Journal of Immunology 195 (12), 5625-5636, 2015 | 85 | 2015 |
The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function M Locci, E Draghici, F Marangoni, M Bosticardo, M Catucci, A Aiuti, ... Journal of Experimental Medicine 206 (4), 735-742, 2009 | 69 | 2009 |
Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells V Schulten, V Tripple, G Seumois, Y Qian, RH Scheuermann, Z Fu, ... Journal of Allergy and Clinical Immunology 141 (2), 775-777. e6, 2018 | 63 | 2018 |
CD4+ follicular regulatory T cells optimize the influenza virus–specific B cell response Y Lu, R Jiang, AW Freyn, J Wang, S Strohmeier, K Lederer, M Locci, ... Journal of Experimental Medicine 218 (3), e20200547, 2020 | 48 | 2020 |
Development of an mRNA-lipid nanoparticle vaccine against Lyme disease M Pine, G Arora, TM Hart, E Bettini, BT Gaudette, H Muramatsu, ... Molecular Therapy 31 (9), 2702-2714, 2023 | 47 | 2023 |
Lentiviral-mediated gene therapy leads to improvement of B-cell functionality in a murine model of Wiskott-Aldrich syndrome M Bosticardo, E Draghici, F Schena, AV Sauer, E Fontana, MC Castiello, ... Journal of allergy and clinical immunology 127 (6), 1376-1384. e5, 2011 | 44 | 2011 |
CRISPR-Mediated Slamf1Δ/Δ Slamf5Δ/Δ Slamf6Δ/Δ Triple Gene Disruption Reveals NKT Cell Defects but Not T Follicular Helper Cell Defects. JK Hu, JC Crampton, M Locci, S Crotty PLoS One, 2016 | 19 | 2016 |