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Róisín M. McManus
Róisín M. McManus
Institute of Innate Immunity, University of Bonn and DZNE, Bonn
在 tcd.ie 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
NLRP3 inflammasome activation drives tau pathology
C Ising, C Venegas, S Zhang, H Scheiblich, SV Schmidt, A Vieira-Saecker, ...
Nature 575 (7784), 669-673, 2019
9652019
Inflammasome signalling in brain function and neurodegenerative disease
MT Heneka, RM McManus, E Latz
Nature Reviews Neuroscience 19 (10), 610-621, 2018
6172018
IFN-γ production by amyloid β–specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer’s disease
TC Browne, K McQuillan, RM McManus, JA O’Reilly, KHG Mills, MA Lynch
The Journal of Immunology 190 (5), 2241-2251, 2013
3032013
Role of neuroinflammation in neurodegeneration: new insights
RM McManus, MT Heneka
Alzheimer's research & therapy 9, 1-7, 2017
2572017
Targeting neuroinflammation to treat Alzheimer’s disease
A Ardura-Fabregat, E Boddeke, A Boza-Serrano, S Brioschi, ...
CNS drugs 31, 1057-1082, 2017
2412017
Lung CD4 tissue-resident memory T cells mediate adaptive immunity induced by previous infection of mice with Bordetella pertussis
MM Wilk, A Misiak, RM McManus, AC Allen, MA Lynch, KHG Mills
The Journal of Immunology 199 (1), 233-243, 2017
1562017
Soluble Aβ oligomers and protofibrils induce NLRP3 inflammasome activation in microglia
A Lučiūnaitė, RM McManus, M Jankunec, I Rácz, C Dansokho, ...
Journal of neurochemistry 155 (6), 650-661, 2020
1312020
Respiratory infection promotes T cell infiltration and amyloid-β deposition in APP/PS1 mice
RM McManus, SC Higgins, KHG Mills, MA Lynch
Neurobiology of aging 35 (1), 109-121, 2014
1312014
How location and cellular signaling combine to activate the NLRP3 inflammasome
A Akbal, A Dernst, M Lovotti, MSJ Mangan, RM McManus, E Latz
Cellular & molecular immunology 19 (11), 1201-1214, 2022
662022
T cells—protective or pathogenic in Alzheimer’s disease?
RM McManus, KHG Mills, MA Lynch
Journal of Neuroimmune Pharmacology 10, 547-560, 2015
442015
FTY720 attenuates infection-induced enhancement of Aβ accumulation in APP/PS1 mice by modulating astrocytic activation
RM McManus, OM Finucane, MM Wilk, KHG Mills, MA Lynch
Journal of Neuroimmune Pharmacology 12, 670-681, 2017
312017
Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer’s disease
F Brosseron, A Maass, L Kleineidam, KA Ravichandran, PG González, ...
Neuron 110 (6), 1009-1022. e4, 2022
302022
The age-related neuroinflammatory environment promotes macrophage activation, which negatively impacts synaptic function
DA Costello, K Keenan, RM McManus, A Falvey, MA Lynch
Neurobiology of aging 43, 140-148, 2016
262016
Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer’s disease: results from the DELCODE study
F Brosseron, A Maass, L Kleineidam, KA Ravichandran, CC Kolbe, ...
Alzheimer's research & therapy 15 (1), 13, 2023
172023
p38 inhibition decreases Tau toxicity in microglia and improves their phagocytic function
JR Perea, M Bolós, R Cuadros, E García, V García-Escudero, ...
Molecular neurobiology 59 (3), 1632-1648, 2022
122022
T cells in Alzheimer's disease: space invaders
RM McManus, MT Heneka
The Lancet Neurology 19 (4), 285-287, 2020
122020
Author correction: inflammasome signalling in brain function and neurodegenerative disease
MT Heneka, RM McManus, E Latz
Nature Reviews Neuroscience 20 (3), 187-187, 2019
112019
The role of immunity in Alzheimer's disease
RM McManus
Advanced Biology 6 (5), 2101166, 2022
102022
NLRP3‐directed antisense oligonucleotides reduce microglial immunoactivities in vitro
C Braatz, MP Komes, KA Ravichandran, MG de Fragas, A Griep, ...
Journal of Neurochemistry, 2023
62023
NLRP3-mediated glutaminolysis regulates microglia in Alzheimer's disease
R McManus, MP Komes, A Griep, F Santarelli, S Schwartz, JR Perea, ...
32022
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