| Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice S Tanaka, H Hikita, T Tatsumi, R Sakamori, Y Nozaki, S Sakane, Y Shiode, ... Hepatology 64 (6), 1994-2014, 2016 | 311 | 2016 |
| Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma H Murai, T Kodama, K Maesaka, S Tange, D Motooka, Y Suzuki, ... Hepatology 77 (1), 77-91, 2023 | 68 | 2023 |
| Bak deficiency inhibits liver carcinogenesis: a causal link between apoptosis and carcinogenesis H Hikita, T Kodama, S Shimizu, W Li, M Shigekawa, S Tanaka, A Hosui, ... Journal of hepatology 57 (1), 92-100, 2012 | 62 | 2012 |
| DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway Y Saito, H Hikita, Y Nozaki, Y Kai, Y Makino, T Nakabori, S Tanaka, ... Cell Death & Differentiation 26 (3), 470-486, 2019 | 52 | 2019 |
| ST6GAL1 is a novel serum biomarker for lenvatinib-susceptible FGF19-driven hepatocellular carcinoma Y Myojin, T Kodama, K Maesaka, D Motooka, Y Sato, S Tanaka, Y Abe, ... Clinical Cancer Research 27 (4), 1150-1161, 2021 | 47 | 2021 |
| Interleukin-6 is a circulating prognostic biomarker for hepatocellular carcinoma patients treated with combined immunotherapy Y Myojin, T Kodama, R Sakamori, K Maesaka, T Matsumae, Y Sawai, ... Cancers 14 (4), 883, 2022 | 45 | 2022 |
| Carbamazepine promotes liver regeneration and survival in mice T Kawaguchi, T Kodama, H Hikita, S Tanaka, M Shigekawa, T Nawa, ... Journal of Hepatology 59 (6), 1239-1245, 2013 | 35 | 2013 |
| Emergence of hepatitis C virus NS5A L31V plus Y93H variant upon treatment failure of daclatasvir and asunaprevir is relatively resistant to ledipasvir and NS5B polymerase … Y Kai, H Hikita, T Tatsumi, T Nakabori, Y Saito, N Morishita, S Tanaka, ... Journal of gastroenterology 50, 1145-1151, 2015 | 32 | 2015 |
| Activation of the mitochondrial apoptotic pathway produces reactive oxygen species and oxidative damage in hepatocytes that contribute to liver tumorigenesis H Hikita, T Kodama, S Tanaka, Y Saito, Y Nozaki, T Nakabori, S Shimizu, ... Cancer Prevention Research 8 (8), 693-701, 2015 | 31 | 2015 |
| S100A8 production in CXCR2-expressing CD11b+ Gr-1high cells aggravates hepatitis in mice fed a high-fat and high-cholesterol diet K Mukai, T Miyagi, K Nishio, Y Yokoyama, T Yoshioka, Y Saito, S Tanaka, ... The Journal of Immunology 196 (1), 395-406, 2016 | 30 | 2016 |
| Outbreak of hepatitis A linked to European outbreaks among men who have sex with men in Osaka, Japan, from March to July 2018 S Tanaka, T Kishi, A Ishihara, D Watanabe, T Uehira, H Ishida, ... Hepatology Research 49 (6), 705-710, 2019 | 29 | 2019 |
| Sodium taurocholate cotransporting polypeptide inhibition efficiently blocks hepatitis B virus spread in mice with a humanized liver T Nakabori, H Hikita, K Murai, Y Nozaki, Y Kai, Y Makino, Y Saito, ... Scientific reports 6 (1), 27782, 2016 | 26 | 2016 |
| Hepatitis C virus enhances Rubicon expression, leading to autophagy inhibition and intracellular innate immune activation Y Shiode, H Hikita, S Tanaka, K Shirai, A Doi, S Sakane, Y Kai, ... Scientific reports 10 (1), 15290, 2020 | 16 | 2020 |
| The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver T Kodama, H Hikita, T Kawaguchi, Y Saito, S Tanaka, M Shigekawa, ... Journal of Biological Chemistry 288 (42), 30009-30018, 2013 | 14 | 2013 |
| Synthetic lethal interaction of combined CD26 and Bcl‐xL inhibition is a powerful anticancer therapy against hepatocellular carcinoma T Kawaguchi, T Kodama, H Hikita, Y Makino, Y Saito, S Tanaka, ... Hepatology Research 45 (9), 1023-1033, 2015 | 13 | 2015 |
| Hepatitis B virus reactivation associated with temozolomide for malignant glioma: a case report and recommendation for prophylaxis Y Fujimoto, N Hashimoto, M Kinoshita, Y Miyazaki, S Tanaka, ... International journal of clinical oncology 17, 290-293, 2012 | 13 | 2012 |
| TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation Y Shiode, T Kodama, S Shigeno, K Murai, S Tanaka, JY Newberg, ... Hepatology 77 (2), 395-410, 2023 | 11 | 2023 |
| Serum amyloid P component and pro-platelet basic protein in extracellular vesicles or serum are novel markers of liver fibrosis in chronic hepatitis C patients K Shirai, H Hikita, S Sakane, R Narumi, J Adachi, A Doi, S Tanaka, ... PLoS One 17 (7), e0271020, 2022 | 7 | 2022 |
| Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver … Y Nozaki, H Hikita, S Tanaka, K Fukumoto, M Urabe, K Sato, Y Myojin, ... Scientific Reports 11 (1), 3363, 2021 | 5 | 2021 |
| Favorable outcome with direct‐acting antiviral treatment in hepatitis C patients coinfected with HIV H Ishida, A Ishihara, S Tanaka, T Iwasaki, H Hasegawa, T Akasaka, ... Hepatology Research 49 (9), 1076-1082, 2019 | 5 | 2019 |
