A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers KN Kodumudi, K Woan, DL Gilvary, E Sahakian, S Wei, JY Djeu Clinical cancer research 16 (18), 4583-4594, 2010 | 599 | 2010 |
Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth JA Bergman, K Woan, P Perez-Villarroel, A Villagra, EM Sotomayor, ... Journal of medicinal chemistry 55 (22), 9891-9899, 2012 | 250 | 2012 |
Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells F Cheng, M Lienlaf, P Perez-Villarroel, HW Wang, C Lee, K Woan, ... Molecular immunology 60 (1), 44-53, 2014 | 158 | 2014 |
Essential role of HDAC6 in the regulation of PD-L1 in melanoma M Lienlaf, P Perez-Villarroel, T Knox, M Pabon, E Sahakian, J Powers, ... Molecular oncology 10 (5), 735-750, 2016 | 155 | 2016 |
Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: enhanced antitumor immunity and impaired cell proliferation KV Woan, M Lienlaf, P Perez-Villaroel, C Lee, F Cheng, T Knox, ... Molecular oncology 9 (7), 1447-1457, 2015 | 155 | 2015 |
The anti-melanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity DM Woods, K Woan, F Cheng, H Wang, P Perez-Villarroel, C Lee, ... Melanoma research 23 (5), 341, 2013 | 134 | 2013 |
Histone deacetylase 11: a novel epigenetic regulator of myeloid derived suppressor cell expansion and function E Sahakian, JJ Powers, J Chen, SL Deng, F Cheng, A Distler, DM Woods, ... Molecular immunology 63 (2), 579-585, 2015 | 133 | 2015 |
A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs F Cheng, M Lienlaf, HW Wang, P Perez-Villarroel, C Lee, K Woan, ... The Journal of Immunology 193 (6), 2850-2862, 2014 | 123 | 2014 |
Modulation of antigen‐presenting cells by HDAC inhibitors: implications in autoimmunity and cancer KV Woan, E Sahakian, EM Sotomayor, E Seto, A Villagra Immunology and cell biology 90 (1), 55-65, 2012 | 81 | 2012 |
T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model DM Woods, KV Woan, F Cheng, AL Sodré, D Wang, Y Wu, Z Wang, ... Blood 130 (2), 146-155, 2017 | 72 | 2017 |
Histone deacetylase inhibitor LAQ824 augments inflammatory responses in macrophages through transcriptional regulation of IL-10 H Wang, F Cheng, K Woan, E Sahakian, O Merino, J Rock-Klotz, ... The Journal of Immunology 186 (7), 3986-3996, 2011 | 69 | 2011 |
Stat3 inhibition augments the immunogenicity of B-cell lymphoma cells, leading to effective antitumor immunity F Cheng, H Wang, P Horna, Z Wang, B Shah, E Sahakian, KV Woan, ... Cancer research 72 (17), 4440-4448, 2012 | 20 | 2012 |
Selective histone deactylase 6 inhibitors EM Sotomayor, JA Bergman, AP Kozikowski, AV Villagra, KV Woan US Patent 9,751,832, 2017 | 6 | 2017 |
Selective histone deactylase 6 inhibitors EM Sotomayor, J Bergman, A Kozikowski, KV Woan, AV Villagra US Patent 9,409,858, 2016 | 6 | 2016 |
Selective histone deactylase 6 inhibitors EM Sotomayor, JA Bergman, AP Kozikowski, AV Lagra, KV Woan US Patent App. 14/907,321, 2016 | 6 | 2016 |
Selective histone deactylase 6 inhibitors EM Sotomayor, J Bergman, A Kozikowski, KV Woan, AV Villagra US Patent App. 14/383,418, 2015 | 6 | 2015 |
Epigenetic modulation of STAT3 by histone deacetylase 6 (HDAC6) regulates IL-10 gene expression and immune tolerance mediated by antigen-presenting cells (APCs) F Cheng, Z Wang, H Wang, KV Woan, E Sahakian, JR Klotz, L Wang, ... Blood 118 (21), 519-519, 2011 | 5 | 2011 |
HDAC profiling in mantle cell lymphoma unveils HDAC11 and HDAC10 as potential molecular targets BD Shah, A Villagra, O Merino, J Rock-Klotz, K Woan, E Seto, P Martin, ... Blood 116 (21), 2506-2506, 2010 | 5 | 2010 |
Histone deacetylase 11 is an epigenetic regulator of cytotoxic T-lymphocyte effector function and memory formation (P1404) D Woods, K Woan, D Wang, Y Yu, J Powers, E Sahakian, F Cheng, ... The Journal of Immunology 190 (1 Supplement), 117.2-117.2, 2013 | 3 | 2013 |
The opposing role of histone deacetylase 10 (HDAC10) and HDAC11 in proliferation/survival of mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL) E Sahakian, BD Shah, J Powers, S Deng, O Merino, A Gill, J Rock-Klotz, ... Blood (ASH Annual Meeting Abstracts) 118 (21), 1363, 2011 | 3 | 2011 |