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Melanie Coombs
Melanie Coombs
Associate Professor Biology, Acadia University
在 acadiau.ca 的电子邮件经过验证 - 首页
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引用次数
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Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress
PB Yaffe, MR Power Coombs, CD Doucette, M Walsh, DW Hoskin
Molecular carcinogenesis 54 (10), 1070-1085, 2015
1962015
Apigenin inhibits the inducible expression of programmed death ligand 1 by human and mouse mammary carcinoma cells
MRP Coombs, ME Harrison, DW Hoskin
Cancer letters 380 (2), 424-433, 2016
1132016
Anticancer activities of natural and synthetic peptides
AL Hilchie, DW Hoskin, MR Power Coombs
Antimicrobial Peptides: Basics for Clinical Application, 131-147, 2019
1082019
TLR2 Mediates Recognition of Live Staphylococcus epidermidis and Clearance of Bacteremia
T Strunk, MR Power Coombs, AJ Currie, P Richmond, DT Golenbock, ...
PloS one 5 (4), e10111, 2010
892010
Exposure of breast cancer cells to a subcytotoxic dose of apigenin causes growth inhibition, oxidative stress, and hypophosphorylation of Akt
ME Harrison, MRP Coombs, LM Delaney, DW Hoskin
Experimental and Molecular Pathology 97 (2), 211-217, 2014
712014
A Neonatal Model of Intravenous Staphylococcus epidermidis Infection in Mice <24 h Old Enables Characterization of Early Innate Immune Responses
KD Kronforst, CJ Mancuso, M Pettengill, J Ninkovic, MR Power Coombs, ...
Public Library of Science 7 (9), e43897, 2012
572012
Structure–function relationships in histidine-rich antimicrobial peptides from Atlantic cod
M McDonald, M Mannion, D Pike, K Lewis, A Flynn, AM Brannan, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (7), 1451-1461, 2015
532015
Neonatal host defense against staphylococcal infections
MR Power Coombs, K Kronforst, O Levy
Journal of Immunology Research 2013 (1), 826303, 2013
482013
Examining the natural role of amphibian antimicrobial peptide magainin
KAM McMillan, MRP Coombs
Molecules 25 (22), 5436, 2020
472020
Adenosine modulates Toll-like receptor function: basic mechanisms and translational opportunities
MR Power Coombs, ME Belderbos, LC Gallington, L Bont, O Levy
Expert review of anti-infective therapy 9 (2), 261-269, 2011
422011
Curcumin blocks interleukin (IL)-2 signaling in T-lymphocytes by inhibiting IL-2 synthesis, CD25 expression, and IL-2 receptor signaling
NA Forward, DM Conrad, MRP Coombs, CD Doucette, SJ Furlong, TJ Lin, ...
Biochemical and Biophysical Research Communications 407 (4), 801-806, 2011
382011
Differential inhibition of T lymphocyte proliferation and cytokine synthesis by [6]‐Gingerol,[8]‐Gingerol, and [10]‐Gingerol
M Bernard, SJ Furlong, MR Power Coombs, DW Hoskin
Phytotherapy Research 29 (11), 1707-1713, 2015
362015
4T1 murine mammary carcinoma cells enhance macrophage-mediated innate inflammatory responses
L Madera, A Greenshields, MRP Coombs, DW Hoskin
PloS one 10 (7), e0133385, 2015
342015
Inhibitory effect of iron withdrawal by chelation on the growth of human and murine mammary carcinoma and fibrosarcoma cells
MRP Coombs, T Grant, AL Greenshields, DJ Arsenault, BE Holbein, ...
Experimental and Molecular Pathology 99 (2), 262-270, 2015
322015
Three-dimensional rockfall shape back analysis: Methods and implications
DA Bonneau, DJ Hutchinson, PM DiFrancesco, M Coombs, Z Sala
Natural Hazards and Earth System Sciences 19 (12), 2745-2765, 2019
312019
Pleurocidin-family cationic antimicrobial peptides mediate lysis of multiple myeloma cells and impair the growth of multiple myeloma xenografts
AL Hilchie, DM Conrad, MR Power Coombs, T Zemlak, CD Doucette, ...
Leukemia & lymphoma 54 (10), 2255-2262, 2013
282013
Docosahexaenoic acid-acylated phloridzin, a novel polyphenol fatty acid ester derivative, is cytotoxic to breast cancer cells
W Fernando, MRP Coombs, DW Hoskin, HPV Rupasinghe
Carcinogenesis 37 (10), 1004-1013, 2016
232016
The prostaglandin E2 pathway and breast cancer stem cells: evidence of increased signaling and potential targeting
OL Walker, ML Dahn, MR Power Coombs, P Marcato
Frontiers in Oncology 11, 791696, 2022
182022
Regulation of macrophage-associated inflammatory responses by species-specific lactoferricin peptides
A Malone, RF Clark, DW Hoskin, MRP Coombs
Frontiers in Bioscience-Landmark 27 (2), 43, 2022
152022
Thy-1 (CD90) signaling preferentially promotes RORγt expression and a Th17 response
S Furlong, MRP Coombs, J Ghassemi-Rad, DW Hoskin
Frontiers in Cell and Developmental Biology 6, 158, 2018
122018
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