Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction VV Senatorov, AR Friedman, DZ Milikovsky, J Ofer, R Saar-Ashkenazy, ... Science Translational Medicine 11 (521), 2019 | 204 | 2019 |
Simulated microgravity and 3D culture enhance induction, viability, proliferation and differentiation of cardiac progenitors from human pluripotent stem cells R Jha, Q Wu, M Singh, MK Preininger, P Han, G Ding, HC Cho, H Jo, ... Scientific Reports 6, 30956, 2016 | 89 | 2016 |
Microscale generation of cardiospheres promotes robust enrichment of cardiomyocytes derived from human pluripotent stem cells DC Nguyen, TA Hookway, Q Wu, R Jha, MK Preininger, X Chen, ... Stem Cell Reports 3 (2), 260-268, 2014 | 81 | 2014 |
Pathological conditioning of human neutrophils recruited to the airway milieu in cystic fibrosis OA Forrest, SA Ingersoll, MK Preininger, J Laval, DH Limoli, MR Brown, ... Journal of Leukocyte Biology 104 (4), 665-675, 2018 | 80 | 2018 |
Mature cystic fibrosis airway neutrophils suppress T cell function: evidence for a role of arginase 1, but not programmed death-ligand 1 SA Ingersoll, J Laval, OA Forrest, MK Preininger, MR Brown, D Arafat, ... The Journal of Immunology 194 (11), 5520-5528, 2015 | 79 | 2015 |
Blood-informative transcripts define nine common axes of peripheral blood gene expression MK Preininger, D Arafat, J Kim, AP Nath, Y Idaghdour, KL Brigham, ... PLOS Genetics 9 (3), e1003362, 2013 | 64 | 2013 |
A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses MK Preininger, R Jha, JT Maxwell, Q Wu, M Singh, B Wang, A Dalal, ... Disease Models and Mechanisms 9 (9), 927-939, 2016 | 63 | 2016 |
Targeting HIF-1α in combination with PPARα activation and postnatal factors promotes the metabolic maturation of human induced pluripotent stem cell-derived cardiomyocytes C Gentillon, D Li, M Duan, WM Yu, MK Preininger, R Jha, A Rampoldi, ... Journal of Molecular and Cellular Cardiology 132, 120-135, 2019 | 59 | 2019 |
Blood–brain barrier dysfunction and astrocyte senescence as reciprocal drivers of neuropathology in aging MK Preininger, D Kaufer International Journal of Molecular Sciences 23 (11), 6217, 2022 | 31 | 2022 |
Targeted elimination of tumorigenic human pluripotent stem cells using suicide-inducing virus-like particles MK Preininger*, A Rampoldi*, SN Crooke*, R Jha, J Maxwell, L Ding, ... ACS Chemical Biology 13 (8), 2329–2338, 2018 | 19 | 2018 |
Cryopreservation of human pluripotent stem cell-derived cardiomyocytes: strategies, challenges, and future directions MK Preininger, M Singh, C Xu Advances in Experimental Medicine and Biology 941, 123-135, 2016 | 18 | 2016 |
Downregulation of LGR5 expression inhibits cardiomyocyte differentiation and potentiates endothelial differentiation from human pluripotent stem cells R Jha, M Singh, Q Wu, C Gentillon, MK Preininger, C Xu Stem Cell Reports 9 (2), 513-527, 2017 | 15 | 2017 |
Blood-brain barrier dysfunction promotes astrocyte senescence through albumin-induced TGFβ signaling activation MK Preininger, D Zaytseva, JM Lin, D Kaufer Aging Cell 22 (2), e13747, 2023 | 11 | 2023 |
Geographical, environmental and pathophysiological influences on the human blood transcriptome R Tabassum, A Nath, MK Preininger, G Gibson Current Genetic Medicine Reports 1 (4), 203-211, 2013 | 10 | 2013 |
Phf15—a novel transcriptional repressor regulating inflammation in mouse microglia SE Muroy, GA Timblin, MK Preininger, P Cedillo, K Saijo Neuroimmunology and Neuroinflammation 7, 166-182, 2020 | 2 | 2020 |
Arginase-1 and programmed cell death ligand-1, potent inducers of immune tolerance, are upregulated on airway neutrophils in cystic fibrosis S Ingersoll, J Laval, MK Preininger, M Brown, R Tirouvanziam Pediatric Pulmonology 48 (S36), 258-258, 2013 | 1 | 2013 |
In vitro transmigration of neutrophils into CF airway fluid induces functional and metabolic reprogramming characteristic of CF airway neutrophils in vivo OA Forrest, S Ingersoll, M Preininger, J Laval, D Limoli, MR Brown, F Lee, ... Pediatric Pulmonology 51 (S45), 241-241, 2016 | | 2016 |
Functional and metabolic reprogramming drives the development of a pathogenic subset of neutrophils in inflammatory airway diseases O Forrest, S Ingersoll, M Preininger, J Laval, D Limoli, M Brown, F Lee, ... European Journal of Immunology 46 (S1), 251-252, 2016 | | 2016 |
Induced pluripotent stem cell-derived cardiomyocytes recapitulate clinically observed refractoriness to therapeutic β-blockade in a patient-specific model of catecholaminergic … MK Preininger, R Jha, Q Wu, M Singh, JT Maxwell, B Wang, PS Fischbach, ... Circulation 132 (S3), A15566, 2015 | | 2015 |
Increased survival and exocytosis of toxic primary granules by neutrophils in an in vitro model of cystic fibrosis airway disease O Forrest, S Ingersoll, M Preininger, J Laval, M Brown, R Tirouvanziam The Journal of Immunology 194 (S1), 192-192, 2015 | | 2015 |