Advances in biomaterials for drug delivery OS Fenton, KN Olafson, PS Pillai, MJ Mitchell, R Langer Advanced Materials 30 (29), 1705328, 2018 | 747 | 2018 |
Optimization of lipid nanoparticle formulations for mRNA delivery in vivo with fractional factorial and definitive screening designs KJ Kauffman, JR Dorkin, JH Yang, MW Heartlein, F DeRosa, FF Mir, ... Nano letters 15 (11), 7300-7306, 2015 | 632 | 2015 |
Lipid nanoparticle assisted mRNA delivery for potent cancer immunotherapy MA Oberli, AM Reichmuth, JR Dorkin, MJ Mitchell, OS Fenton, A Jaklenec, ... Nano letters 17 (3), 1326-1335, 2017 | 620 | 2017 |
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity KA Whitehead, JR Dorkin, AJ Vegas, PH Chang, O Veiseh, J Matthews, ... Nature communications 5 (1), 4277, 2014 | 527 | 2014 |
Polymer–lipid nanoparticles for systemic delivery of mRNA to the lungs JC Kaczmarek, AK Patel, KJ Kauffman, OS Fenton, MJ Webber, ... Angewandte Chemie 128 (44), 14012-14016, 2016 | 307 | 2016 |
Bioinspired alkenyl amino alcohol ionizable lipid materials for highly potent in vivo mRNA delivery OS Fenton, KJ Kauffman, RL McClellan, EA Appel, JR Dorkin, MW Tibbitt, ... Advanced materials (Deerfield Beach, Fla.) 28 (15), 2939, 2016 | 219 | 2016 |
Synthesis and biological evaluation of ionizable lipid materials for the in vivo delivery of messenger RNA to B lymphocytes OS Fenton, KJ Kauffman, JC Kaczmarek, RL McClellan, S Jhunjhunwala, ... Advanced Materials 29 (33), 1606944, 2017 | 206 | 2017 |
Optimization of a degradable polymer–lipid nanoparticle for potent systemic delivery of mRNA to the lung endothelium and immune cells JC Kaczmarek, KJ Kauffman, OS Fenton, K Sadtler, AK Patel, ... Nano letters 18 (10), 6449-6454, 2018 | 178 | 2018 |
Biomanufacturing for clinically advanced cell therapies A Aijaz, M Li, D Smith, D Khong, C LeBlon, OS Fenton, RM Olabisi, ... Nature biomedical engineering 2 (6), 362-376, 2018 | 170 | 2018 |
C7-derivatization of C3-alkylindoles including tryptophans and tryptamines RP Loach, OS Fenton, K Amaike, DS Siegel, E Ozkal, M Movassaghi The Journal of organic chemistry 79 (22), 11254-11263, 2014 | 114 | 2014 |
Exploiting electrostatic interactions in polymer–nanoparticle hydrogels EA Appel, MW Tibbitt, JM Greer, OS Fenton, K Kreuels, DG Anderson, ... ACS Macro Letters 4 (8), 848-852, 2015 | 103 | 2015 |
Engineering a 3D-bioprinted model of human heart valve disease using nanoindentation-based biomechanics DC Van der Valk, CFT Van der Ven, MC Blaser, JM Grolman, PJ Wu, ... Nanomaterials 8 (5), 296, 2018 | 93 | 2018 |
Customizable lipid nanoparticle materials for the delivery of siRNAs and mRNAs OS Fenton, KJ Kauffman, RL McClellan, JC Kaczmarek, MD Zeng, ... Angewandte Chemie International Edition 57 (41), 13582-13586, 2018 | 78 | 2018 |
Poly(β‐amino ester)‐co‐poly(caprolactone) Terpolymers as Nonviral Vectors for mRNA Delivery In Vitro and In Vivo U Capasso Palmiero, JC Kaczmarek, OS Fenton, DG Anderson Advanced Healthcare Materials 7 (14), 1800249, 2018 | 69 | 2018 |
Injectable polymer–nanoparticle hydrogels for local immune cell recruitment OS Fenton, MW Tibbitt, EA Appel, S Jhunjhunwala, MJ Webber, R Langer Biomacromolecules 20 (12), 4430-4436, 2019 | 65 | 2019 |
Concise Total Synthesis of (+)-Asperazine, (+)-Pestalazine A, and (+)-iso-Pestalazine A. Structure Revision of (+)-Pestalazine A RP Loach, OS Fenton, M Movassaghi Journal of the American Chemical Society 138 (3), 1057-1064, 2016 | 63 | 2016 |
A nanoprimer to improve the systemic delivery of siRNA and mRNA NRM Saunders, MS Paolini, OS Fenton, L Poul, J Devalliere, F Mpambani, ... Nano Letters 20 (6), 4264-4269, 2020 | 62 | 2020 |
Rapid classification of simulated street drug mixtures using Raman spectroscopy and principal component analysis KY Noonan, LA Tonge, OS Fenton, DB Damiano, KA Frederick Applied Spectroscopy 63 (7), 742-747, 2009 | 45 | 2009 |
β‐Aminoacrylate Synthetic Hydrogels: Easily Accessible and Operationally Simple Biomaterials Networks OS Fenton, JL Andresen, M Paolini, R Langer Angewandte Chemie 130 (49), 16258-16261, 2018 | 42 | 2018 |
Polymers for extended-release administration MS Paolini, OS Fenton, C Bhattacharya, JL Andresen, R Langer Biomedical Microdevices 21, 1-24, 2019 | 35 | 2019 |