Developability index: a rapid in silico tool for the screening of antibody aggregation propensity TM Lauer, NJ Agrawal, N Chennamsetty, K Egodage, B Helk, BL Trout Journal of pharmaceutical sciences 101 (1), 102-115, 2012 | 219 | 2012 |
Gas solubility of H2S and CO2 in aqueous solutions of N-methyldiethanolamine PJG Huttenhuis, NJ Agrawal, JA Hogendoorn, GF Versteeg Journal of Petroleum Science and Engineering 55 (1-2), 122-134, 2007 | 196 | 2007 |
Aggregation in protein-based biotherapeutics: computational studies and tools to identify aggregation-prone regions NJ Agrawal, S Kumar, X Wang, B Helk, SK Singh, BL Trout Journal of pharmaceutical sciences 100 (12), 5081-5095, 2011 | 153 | 2011 |
Computational tool for the early screening of monoclonal antibodies for their viscosities NJ Agrawal, B Helk, S Kumar, N Mody, HA Sathish, HS Samra, PM Buck, ... MAbs 8 (1), 43-48, 2016 | 95 | 2016 |
Rational design of therapeutic mAbs against aggregation through protein engineering and incorporation of glycosylation motifs applied to bevacizumab F Courtois, NJ Agrawal, TM Lauer, BL Trout MAbs 8 (1), 99-112, 2016 | 94 | 2016 |
Systems biology and physical biology of clathrin-mediated endocytosis V Ramanan, NJ Agrawal, J Liu, S Engles, R Toy, R Radhakrishnan Integrative Biology 3 (8), 803-815, 2011 | 80 | 2011 |
The solubility of carbon dioxide in aqueous N-methyldiethanolamine solutions PJG Huttenhuis, NJ Agrawal, E Solbraa, GF Versteeg Fluid phase equilibria 264 (1-2), 99-112, 2008 | 79 | 2008 |
Fast and scalable purification of a therapeutic full‐length antibody based on process crystallization B Smejkal, NJ Agrawal, B Helk, H Schulz, M Giffard, M Mechelke, F Ortner, ... Biotechnology and bioengineering 110 (9), 2452-2461, 2013 | 67 | 2013 |
Computational methods to predict therapeutic protein aggregation PM Buck, S Kumar, X Wang, NJ Agrawal, BL Trout, SK Singh Therapeutic proteins: Methods and protocols, 425-451, 2012 | 67 | 2012 |
Minimal mesoscale model for protein-mediated vesiculation in clathrin-dependent endocytosis NJ Agrawal, J Nukpezah, R Radhakrishnan PLoS computational biology 6 (9), e1000926, 2010 | 62 | 2010 |
Multivalent binding of nanocarrier to endothelial cells under shear flow J Liu, NJ Agrawal, A Calderon, PS Ayyaswamy, DM Eckmann, ... Biophysical journal 101 (2), 319-326, 2011 | 54 | 2011 |
The role of glycocalyx in nanocarrier-cell adhesion investigated using a thermodynamic model and Monte Carlo simulations NJ Agrawal, R Radhakrishnan The Journal of Physical Chemistry C 111 (43), 15848-15856, 2007 | 54 | 2007 |
Rational design of biobetters with enhanced stability F Courtois, CP Schneider, NJ Agrawal, BL Trout Journal of pharmaceutical sciences 104 (8), 2433-2440, 2015 | 50 | 2015 |
Engineered IL-21 cytokine muteins fused to anti-PD-1 antibodies can improve CD8+ T cell function and anti-tumor immunity S Shen, G Sckisel, A Sahoo, A Lalani, DD Otter, J Pearson, J DeVoss, ... Frontiers in Immunology 11, 832, 2020 | 48 | 2020 |
A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations Y Liu, J Purvis, A Shih, J Weinstein, N Agrawal, R Radhakrishnan Annals of biomedical engineering 35, 1012-1025, 2007 | 45 | 2007 |
Solubility of carbon dioxide and hydrogen sulfide in aqueous N-methyldiethanolamine solutions PJG Huttenhuis, NJ Agrawal, GF Versteeg Industrial & engineering chemistry research 48 (8), 4051-4059, 2009 | 39 | 2009 |
Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists ZW Junming Yie, Donghui SHI, David J. Lloyd, Jinghong Wang, Glenn N. SIVITS ... US Patent App. US20170275370A1, 2017 | 32* | 2017 |
A computational tool to predict the evolutionarily conserved protein–protein interaction hot-spot residues from the structure of the unbound protein NJ Agrawal, B Helk, BL Trout FEBS letters 588 (2), 326-333, 2014 | 30 | 2014 |
Mesoscale simulations of curvature-inducing protein partitioning on lipid bilayer membranes in the presence of mean curvature fields J Liu, R Tourdot, V Ramanan, NJ Agrawal, R Radhakrishanan Molecular physics 110 (11-12), 1127-1137, 2012 | 29 | 2012 |
Prediction of the hydrogen peroxide–induced methionine oxidation propensity in monoclonal antibodies NJ Agrawal, A Dykstra, J Yang, H Yue, X Nguyen, C Kolvenbach, ... Journal of Pharmaceutical Sciences 107 (5), 1282-1289, 2018 | 28 | 2018 |