The ageing systemic milieu negatively regulates neurogenesis and cognitive function SA Villeda, J Luo, KI Mosher, B Zou, M Britschgi, G Bieri, TM Stan, ... Nature 477 (7362), 90-94, 2011 | 1951 | 2011 |
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice SA Villeda, KE Plambeck, J Middeldorp, JM Castellano, KI Mosher, J Luo, ... Nature medicine 20 (6), 659-663, 2014 | 1189 | 2014 |
FoxO3 regulates neural stem cell homeostasis VM Renault, VA Rafalski, AA Morgan, DAM Salih, JO Brett, AE Webb, ... Cell stem cell 5 (5), 527-539, 2009 | 648 | 2009 |
Exerkines in health, resilience and disease LS Chow, RE Gerszten, JM Taylor, BK Pedersen, H Van Praag, S Trappe, ... Nature Reviews Endocrinology 18 (5), 273-289, 2022 | 525 | 2022 |
β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis LK Smith, Y He, JS Park, G Bieri, CE Snethlage, K Lin, G Gontier, R Wabl, ... Nature medicine 21 (8), 932-937, 2015 | 502 | 2015 |
Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain AM Horowitz, X Fan, G Bieri, LK Smith, CI Sanchez-Diaz, AB Schroer, ... Science 369 (6500), 167-173, 2020 | 387 | 2020 |
Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival J Luo, F Elwood, M Britschgi, S Villeda, H Zhang, Z Ding, L Zhu, H Alabsi, ... Journal of Experimental Medicine 210 (1), 157-172, 2013 | 261 | 2013 |
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner A Deczkowska, O Matcovitch-Natan, A Tsitsou-Kampeli, S Ben-Hamo, ... Nature communications 8 (1), 717, 2017 | 232 | 2017 |
Tissue-resident group 2 innate lymphoid cells differentiate by layered ontogeny and in situ perinatal priming C Schneider, J Lee, S Koga, RR Ricardo-Gonzalez, JC Nussbaum, ... Immunity 50 (6), 1425-1438. e5, 2019 | 230 | 2019 |
Tet2 rescues age-related regenerative decline and enhances cognitive function in the adult mouse brain G Gontier, M Iyer, JM Shea, G Bieri, EG Wheatley, M Ramalho-Santos, ... Cell reports 22 (8), 1974-1981, 2018 | 189 | 2018 |
Preclinical assessment of young blood plasma for Alzheimer disease J Middeldorp, B Lehallier, SA Villeda, SSM Miedema, E Evans, E Czirr, ... JAMA neurology 73 (11), 1325-1333, 2016 | 163 | 2016 |
Long-term cognitive impairments and pathological alterations in a mouse model of repetitive mild traumatic brain injury J Luo, A Nguyen, S Villeda, H Zhang, Z Ding, D Lindsey, G Bieri, ... Frontiers in neurology 5, 12, 2014 | 162 | 2014 |
Mechanisms of hippocampal aging and the potential for rejuvenation X Fan, EG Wheatley, SA Villeda Annual review of neuroscience 40 (1), 251-272, 2017 | 128 | 2017 |
MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage P Sousa-Victor, J Neves, W Cedron-Craft, PB Ventura, CY Liao, RR Riley, ... Nature metabolism 1 (2), 276-290, 2019 | 119 | 2019 |
Aging and brain rejuvenation as systemic events J Bouchard, SA Villeda Journal of neurochemistry 132 (1), 5-19, 2015 | 114 | 2015 |
ALK5-dependent TGF-β signaling is a major determinant of late-stage adult neurogenesis Y He, H Zhang, A Yung, SA Villeda, PA Jaeger, O Olayiwola, N Fainberg, ... Nature neuroscience 17 (7), 943-952, 2014 | 112 | 2014 |
Complement receptor 2 is expressed in neural progenitor cells and regulates adult hippocampal neurogenesis M Moriyama, T Fukuhara, M Britschgi, Y He, R Narasimhan, S Villeda, ... Journal of Neuroscience 31 (11), 3981-3989, 2011 | 102 | 2011 |
Platelet factors attenuate inflammation and rescue cognition in ageing AB Schroer, PB Ventura, J Sucharov, R Misra, MKK Chui, G Bieri, ... Nature 620 (7976), 1071-1079, 2023 | 96 | 2023 |
Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age D Brigger, C Riether, R van Brummelen, KI Mosher, A Shiu, Z Ding, ... Nature metabolism 2 (8), 688-702, 2020 | 94 | 2020 |
Blood-to-brain communication in aging and rejuvenation G Bieri, AB Schroer, SA Villeda Nature neuroscience 26 (3), 379-393, 2023 | 88 | 2023 |