Design of protein-binding proteins from the target structure alone L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ... Nature 605 (7910), 551-560, 2022 | 281 | 2022 |
Protein crystallization promotes type 2 immunity and is reversible by antibody treatment EK Persson, K Verstraete, I Heyndrickx, E Gevaert, H Aegerter, JM Percier, ... Science 364 (6442), eaaw4295, 2019 | 249 | 2019 |
Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma K Verstraete, F Peelman, H Braun, J Lopez, D Van Rompaey, ... Nature communications 8 (1), 14937, 2017 | 161 | 2017 |
Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle KHG Verschueren, C Blanchet, J Felix, A Dansercoer, D De Vos, Y Bloch, ... Nature 568 (7753), 571-575, 2019 | 143 | 2019 |
Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex K Verstraete, G Vandriessche, M Januar, J Elegheert, AV Shkumatov, ... Blood, The Journal of the American Society of Hematology 118 (1), 60-68, 2011 | 105 | 2011 |
Extracellular assembly and activation principles of oncogenic class III receptor tyrosine kinases K Verstraete, SN Savvides Nature Reviews Cancer 12 (11), 753-766, 2012 | 103 | 2012 |
Structural basis of IL-23 antagonism by an Alphabody protein scaffold J Desmet, K Verstraete, Y Bloch, E Lorent, Y Wen, B Devreese, ... Nature communications 5 (1), 5237, 2014 | 80 | 2014 |
Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis E Gevaert, T Delemarre, J De Volder, N Zhang, G Holtappels, N De Ruyck, ... Journal of Allergy and Clinical Immunology 145 (1), 427-430. e4, 2020 | 72 | 2020 |
Structural basis of the proinflammatory signaling complex mediated by TSLP K Verstraete, L Van Schie, L Vyncke, Y Bloch, J Tavernier, E Pauwels, ... Nature structural & molecular biology 21 (4), 375-382, 2014 | 52 | 2014 |
Molecular and structural basis of glutathione import in Gram‐positive bacteria via GshT and the cystine ABC importer TcyBC of Streptococcus mutans B Vergauwen, K Verstraete, DB Senadheera, A Dansercoer, ... Molecular microbiology 89 (2), 288-303, 2013 | 46 | 2013 |
Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1 J Elegheert, N Bracke, P Pouliot, I Gutsche, AV Shkumatov, N Tarbouriech, ... Nature structural & molecular biology 19 (9), 938-947, 2012 | 44 | 2012 |
Structure and assembly mechanism of the signaling complex mediated by human CSF-1 J Felix, S De Munck, K Verstraete, L Meuris, N Callewaert, J Elegheert, ... Structure 23 (9), 1621-1631, 2015 | 43 | 2015 |
Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles J Elegheert, A Desfosses, AV Shkumatov, X Wu, N Bracke, K Verstraete, ... Structure 19 (12), 1762-1772, 2011 | 41 | 2011 |
Charcot–Leyden crystals and other protein crystals driving type 2 immunity and allergy H Aegerter, U Smole, I Heyndrickx, K Verstraete, SN Savvides, ... Current opinion in immunology 72, 72-78, 2021 | 28 | 2021 |
Efficient Production of Bioactive Recombinant Human Flt3 Ligand in E. coli K Verstraete, S Koch, S Ertugrul, I Vandenberghe, M Aerts, ... The protein journal 28, 57-65, 2009 | 25 | 2009 |
Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF J Felix, E Kandiah, S De Munck, Y Bloch, GC Van Zundert, K Pauwels, ... Nature Communications 7 (1), 13228, 2016 | 22 | 2016 |
Structural and biochemical characterization of an atypical short‐chain dehydrogenase/reductase reveals an unusual cofactor preference G Buysschaert, K Verstraete, SN Savvides, B Vergauwen The FEBS journal 280 (5), 1358-1370, 2013 | 20 | 2013 |
Rare antagonistic leptin variants and severe, early-onset obesity JB Funcke, B Moepps, J Roos, J von Schnurbein, K Verstraete, ... New England Journal of Medicine 388 (24), 2253-2261, 2023 | 15 | 2023 |
Robust de novo design of protein binding proteins from target structural information alone L Cao, B Coventry, I Goreshnik, B Huang, JS Park, KM Jude, I Marković, ... BioRxiv, 2021.09. 04.459002, 2021 | 15 | 2021 |
Mechanism of receptor assembly via the pleiotropic adipokine Leptin A Tsirigotaki, A Dansercoer, KHG Verschueren, I Marković, C Pollmann, ... Nature Structural & Molecular Biology 30 (4), 551-563, 2023 | 13 | 2023 |