Identification of thiotetronic acid antibiotic biosynthetic pathways by target-directed genome mining X Tang, J Li, N Millán-Aguiñaga, JJ Zhang, EC O’Neill, JA Ugalde, ... ACS Chemical Biology 10 (12), 2841-2849, 2015 | 247 | 2015 |
MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters BR Terlouw, K Blin, JC Navarro-Muñoz, NE Avalon, MG Chevrette, ... Nucleic Acids Research 51 (D1), D603-D610, 2023 | 184 | 2023 |
Genetic platforms for heterologous expression of microbial natural products JJ Zhang, X Tang, BS Moore Natural Product Reports 36 (9), 1313-1332, 2019 | 130 | 2019 |
Identification of the bacterial biosynthetic gene clusters of the oral microbiome illuminates the unexplored social language of bacteria during health and disease G Aleti, JL Baker, X Tang, R Alvarez, M Dinis, NC Tran, AV Melnik, ... mBio 10 (2), e00321-19, 2019 | 88 | 2019 |
Screening and isolation of an organic solvent-tolerant bacterium for high-yield production of organic solvent-stable protease X Tang, Y Pan, S Li, B He Bioresource Technology 99 (15), 7388-7392, 2008 | 76 | 2008 |
Identification of a napsamycin biosynthesis gene cluster by genome mining L Kaysser, X Tang, E Wemakor, K Sedding, S Hennig, S Siebenberg, ... ChemBioChem 12 (3), 477-487, 2011 | 61 | 2011 |
Biochemical properties and potential applications of a solvent-stable protease from the high-yield protease producer Pseudomonas aeruginosa PT121 X Tang, B Wu, H Ying, B He Applied Biochemistry and Biotechnology 160, 1017-1031, 2010 | 56 | 2010 |
Direct cloning and heterologous expression of natural product biosynthetic gene clusters by transformation-associated recombination JJ Zhang, K Yamanaka, X Tang, BS Moore Methods in Enzymology 621, 87-110, 2019 | 53 | 2019 |
Broad-host-range expression reveals native and host regulatory elements that influence heterologous antibiotic production in Gram-negative bacteria JJ Zhang, X Tang, M Zhang, D Nguyen, BS Moore mBio 8 (5), e01291-17, 2017 | 51 | 2017 |
Cariogenic Streptococcus mutans produces tetramic acid strain-specific antibiotics that impair commensal colonization X Tang, Y Kudo, JL Baker, S LaBonte, PA Jordan, SMK McKinnie, J Guo, ... ACS Infectious Diseases 6 (4), 563-571, 2020 | 49 | 2020 |
Klebsiella and Providencia emerge as lone survivors following long-term starvation of oral microbiota JL Baker, EL Hendrickson, X Tang, R Lux, X He, A Edlund, JS McLean, ... PNAS 116 (17), 8499-8504, 2019 | 46 | 2019 |
Retrieving and utilizing hypothetical neutral losses from tandem mass spectra for spectral similarity analysis and unknown metabolite annotation S Xing, Y Hu, Z Yin, M Liu, X Tang, M Fang, T Huan Analytical Chemistry 92 (21), 14476-14483, 2020 | 41 | 2020 |
A two-step sulfation in antibiotic biosynthesis requires a type III polyketide synthase X Tang, K Eitel, L Kaysser, A Kulik, S Grond, B Gust Nature Chemical Biology 9 (10), 610-615, 2013 | 41 | 2013 |
Pass-back chain extension expands multimodular assembly line biosynthesis JJ Zhang, X Tang, T Huan, AC Ross, BS Moore Nature Chemical Biology 16 (1), 42-49, 2020 | 40 | 2020 |
Engineering Salinispora tropica for heterologous expression of natural product biosynthetic gene clusters JJ Zhang, BS Moore, X Tang Applied Microbiology and Biotechnology 102, 8437-8446, 2018 | 25 | 2018 |
Minimization of the thiolactomycin biosynthetic pathway reveals that the cytochrome P450 enzyme TlmF is required for five‐membered thiolactone ring formation X Tang, J Li, BS Moore ChemBioChem 18 (12), 1072-1076, 2017 | 22 | 2017 |
Contributions of human-associated archaeal metabolites to tumor microenvironment and carcinogenesis M Cai, S Kandalai, X Tang, Q Zheng Microbiology spectrum 10 (2), e02367-21, 2022 | 20 | 2022 |
Correlational networking guides the discovery of unclustered lanthipeptide protease-encoding genes D Xue, EA Older, Z Zhong, Z Shang, N Chen, N Dittenhauser, L Hou, ... Nature communications 13 (1), 1647, 2022 | 17 | 2022 |
Enzymatic C− H Oxidation–Amidation Cascade in the Production of Natural and Unnatural Thiotetronate Antibiotics with Potentiated Bioactivity J Li, X Tang, T Awakawa, BS Moore Angewandte Chemie International Edition, 2017 | 17 | 2017 |
Catabolic protein degradation in marine sediments confined to distinct archaea X Yin, G Zhou, M Cai, QZ Zhu, T Richter-Heitmann, DA Aromokeye, Y Liu, ... The ISME Journal 16 (6), 1617-1626, 2022 | 16 | 2022 |