Phenylthiourea specifically reduces zebrafish eye size Z Li, D Ptak, L Zhang, EK Walls, W Zhong, YF Leung PloS one 7 (6), e40132, 2012 | 104 | 2012 |
Mesenchymal stem cells for treating ocular surface diseases L Zhang, VJ Coulson-Thomas, TG Ferreira, WWY Kao BMC ophthalmology 15, 55-65, 2015 | 79 | 2015 |
Trimethylamine N-oxide alleviates the severe aggregation and ER stress caused by G98R αA-crystallin B Gong, LY Zhang, CP Pang, DSC Lam, GHF Yam Molecular vision 15, 2829, 2009 | 53 | 2009 |
A novel γD-crystallin mutation causes mild changes in protein properties but leads to congenital coralliform cataract LY Zhang, B Gong, JP Tong, DSP Fan, SWY Chiang, D Lou, DSC Lam, ... Molecular vision 15, 1521, 2009 | 46 | 2009 |
A novel deletion variant of gammaD-crystallin responsible for congenital nuclear cataract LY Zhang, GH Yam, DS Fan, PO Tam, DS Lam, CP Pang Mol Vis 13 (236/37), 2096-2104, 2007 | 46 | 2007 |
ARQiv-HTS, a versatile whole-organism screening platform enabling in vivo drug discovery at high-throughput rates DT White, AU Eroglu, G Wang, L Zhang, S Sengupta, D Ding, ... Nature protocols 11 (12), 2432-2453, 2016 | 42 | 2016 |
NTR 2.0: a rationally engineered prodrug-converting enzyme with substantially enhanced efficacy for targeted cell ablation AV Sharrock, TS Mulligan, KR Hall, EM Williams, DT White, L Zhang, ... Nature methods 19 (2), 205-215, 2022 | 39 | 2022 |
Sodium 4-phenylbutyrate ameliorates the effects of cataract-causing mutant gammaD-crystallin in cultured cells B Gong, LY Zhang, DSC Lam, CP Pang, GHF Yam Molecular vision 16, 997, 2010 | 37 | 2010 |
A Naturally-Derived Compound Schisandrin B Enhanced Light Sensation in the pde6c Zebrafish Model of Retinal Degeneration L Zhang, L Xiang, Y Liu, P Venkatraman, L Chong, J Cho, S Bonilla, ... PloS one 11 (3), e0149663, 2016 | 33 | 2016 |
The role of egr1 in early zebrafish retinogenesis L Zhang, J Cho, D Ptak, YF Leung PloS one 8 (2), e56108, 2013 | 33 | 2013 |
An αA-crystallin gene mutation, Arg12Cys, causing inherited cataract-microcornea exhibits an altered heat-shock response LY Zhang, GHF Yam, POS Tam, RYK Lai, DSC Lam, CP Pang, DSP Fan Molecular vision 15, 1127, 2009 | 31 | 2009 |
A high-throughput zebrafish screening method for visual mutants by light-induced locomotor response Y Gao, RHM Chan, TWS Chow, L Zhang, S Bonilla, CP Pang, M Zhang, ... IEEE/ACM Transactions on Computational Biology and Bioinformatics 11 (4 …, 2014 | 30 | 2014 |
A novel mutation in CRYBB2 responsible for inherited coronary cataract D Lou, JP Tong, LY Zhang, SWY Chiang, DSC Lam, CP Pang Eye 23 (5), 1213-1220, 2009 | 30 | 2009 |
Cellular expression of Smarca4 (Brg1)-regulated genes in zebrafish retinas MR Hensley, F Emran, S Bonilla, L Zhang, W Zhong, P Grosu, JE Dowling, ... BMC developmental biology 11, 1-16, 2011 | 25 | 2011 |
Multiplexed CRISPR/Cas9 targeting of genes implicated in retinal regeneration and degeneration A Unal Eroglu, TS Mulligan, L Zhang, DT White, S Sengupta, C Nie, ... Frontiers in cell and developmental biology 6, 88, 2018 | 20 | 2018 |
Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa L Zhang, C Chen, J Fu, B Lilley, C Berlinicke, B Hansen, D Ding, G Wang, ... Elife 10, e57245, 2021 | 17 | 2021 |
Drug screening with zebrafish visual behavior identifies carvedilol as a potential treatment for an autosomal dominant form of retinitis pigmentosa L Ganzen, MJ Ko, M Zhang, R Xie, Y Chen, L Zhang, R James, J Mumm, ... Scientific reports 11 (1), 11432, 2021 | 17 | 2021 |
Microdissection of zebrafish embryonic eye tissues L Zhang, YF Leung JoVE (Journal of Visualized Experiments), e2028, 2010 | 15 | 2010 |
Perturbed meibomian gland and tarsal plate morphogenesis by excess TGFα in eyelid stroma F Dong, CY Liu, Y Yuan, Y Zhang, W Li, M Call, L Zhang, Y Chen, Z Liu, ... Developmental biology 406 (2), 147-157, 2015 | 11 | 2015 |
Drug Screening to Treat Early-Onset Eye Diseases: Can Zebrafish Expedite the Discovery? L Zhang, L Chong, J Cho, PC Liao, F Shen, YF Leung Asia-Pacific Journal of Ophthalmology 1 (6), 374-383, 2012 | 11 | 2012 |