Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism DAR Valério, TM Cunha, NS Arakawa, HP Lemos, FB Da Costa, ... European journal of pharmacology 562 (1-2), 155-163, 2007 | 133 | 2007 |
Kaurenoic Acid from Sphagneticola trilobata Inhibits Inflammatory Pain: Effect on Cytokine Production and Activation of the NO–Cyclic GMP–Protein Kinase G–ATP … SS Mizokami, NS Arakawa, SR Ambrosio, AC Zarpelon, R Casagrande, ... Journal of Natural Products 75 (5), 896-904, 2012 | 100 | 2012 |
Biotransformation of a tetrahydrofuran lignan by the endophytic fungus Phomopsis Sp. M Verza, NS Arakawa, NP Lopes, MJ Kato, MT Pupo, S Said, I Carvalho Journal of the Brazilian Chemical Society 20, 195-200, 2009 | 67 | 2009 |
Hypericum perforatum Reduces Paracetamol‐Induced Hepatotoxicity and Lethality in Mice by Modulating Inflammation and Oxidative Stress MSN Hohmann, RDR Cardoso, V Fattori, NS Arakawa, JC Tomaz, ... Phytotherapy Research 29 (7), 1097-1101, 2015 | 58 | 2015 |
Pimaradienoic acid inhibits carrageenan-induced inflammatory leukocyte recruitment and edema in mice: Inhibition of oxidative stress, nitric oxide and cytokine production SS Mizokami, MSN Hohmann, L Staurengo-Ferrari, TT Carvalho, ... PLoS One 11 (2), e0149656, 2016 | 51 | 2016 |
Trypanocidal activity of pimarane diterpenes from Viguiera arenaria (Asteraceae) SR Ambrósio, NS Arakawa, VR Esperandim, S de Albuquerque, ... Phytotherapy Research: An International Journal Devoted to Pharmacological …, 2008 | 50 | 2008 |
Dehydroabietic acid isolated from Pinus elliottii exerts in vitro antileishmanial action by pro-oxidant effect, inducing ROS production in promastigote and downregulating Nrf2 … MD Gonçalves, BTS Bortoleti, F Tomiotto-Pellissier, MM Miranda-Sapla, ... Fitoterapia 128, 224-232, 2018 | 41 | 2018 |
Infraspecific variation in the chemistry of glandular trichomes of two Brazilian Viguiera species (Heliantheae; Asteraceae) FB Da Costa, K Schorr, NS Arakawa, EE Schilling, O Spring Journal of the Brazilian Chemical Society 12, 403-407, 2001 | 41 | 2001 |
Kaurenoic Acid Possesses Leishmanicidal Activity by Triggering a NLRP12/IL‐1β/cNOS/NO Pathway MM Miranda, C Panis, SS da Silva, JA Macri, NY Kawakami, ... Mediators of inflammation 2015 (1), 392918, 2015 | 38 | 2015 |
Topical Formulations Containing Pimenta pseudocaryophyllus Extract: In Vitro Antioxidant Activity and In Vivo Efficacy Against UV-B-Induced Oxidative Stress MZ Campanini, DL Custódio, ALM Ivan, SM Martins, MJR Paranzini, ... AAPS PharmSciTech 15, 86-95, 2014 | 37 | 2014 |
Anticariogenic Properties of ent-Pimarane Diterpenes Obtained by Microbial Transformation ME Severiano, MR Simao, TS Porto, CHG Martins, RCS Veneziani, ... Molecules 15 (12), 8553-8566, 2010 | 36 | 2010 |
Budlein A, a Sesquiterpene Lactone From Viguiera robusta, Alleviates Pain and Inflammation in a Model of Acute Gout Arthritis in Mice V Fattori, AC Zarpelon, L Staurengo-Ferrari, SM Borghi, TH Zaninelli, ... Frontiers in pharmacology 9, 1076, 2018 | 33 | 2018 |
Grandiflorenic acid promotes death of promastigotes via apoptosis-like mechanism and affects amastigotes by increasing total iron bound capacity BT da Silva Bortoleti, MD Gonçalves, F Tomiotto-Pellissier, ... Phytomedicine 46, 11-20, 2018 | 29 | 2018 |
Budlein A from Viguiera robusta inhibits leukocyte-endothelial cell interactions, adhesion molecule expression and inflammatory mediators release R Nicolete, NS Arakawa, C Rius, A Nomizo, PJ Jose, FB Da Costa, ... Phytomedicine 16 (10), 904-915, 2009 | 29 | 2009 |
Sesquiterpene lactones: structural diversity and perspectives as anti-inflammatory molecules MSN Hohmann, DT Longhi-Balbinot, CFS Guazelli, SA Navarro, ... Studies in natural products chemistry 49, 243-264, 2016 | 28 | 2016 |
Spray-drying of casein/pectin bioconjugate microcapsules containing grape (Vitis labrusca) by-product extract JB Carra, RLN de Matos, AP Novelli, RO do Couto, F Yamashita, ... Food Chemistry 368, 130817, 2022 | 27 | 2022 |
Trypanocidal activity of copaiba oil and kaurenoic acid does not depend on macrophage killing machinery D Kian, CAC Lancheros, JP Assolini, NS Arakawa, VF Veiga-Júnior, ... Biomedicine & Pharmacotherapy 103, 1294-1301, 2018 | 27 | 2018 |
Further sesquiterpene lactones from Viguiera robusta and the potential anti-inflammatory activity of a heliangolide: inhibition of human neutrophil elastase release NS Arakawa, K Schorr, SR Ambrosio, I Merfort, FB Da Costa Zeitschrift für Naturforschung C 63 (7-8), 533-538, 2008 | 27 | 2008 |
Fungal transformation and schistosomicidal effects of pimaradienoic acid TS Porto, AA da Silva Filho, LG Magalhães, RA dos Santos, ... Chemistry & Biodiversity 9 (8), 1465-1474, 2012 | 26 | 2012 |
Pimarane‐type diterpenes obtained by biotransformation: antimicrobial properties against clinically isolated Gram‐positive multidrug‐resistant bacteria TS Porto, MR Simão, LZ Carlos, CHG Martins, NAJC Furtado, S Said, ... Phytotherapy Research 27 (10), 1502-1507, 2013 | 21 | 2013 |