Epithelial‐mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients TZ Tan, QH Miow, Y Miki, T Noda, S Mori, RYJ Huang, JP Thiery EMBO molecular medicine 6 (10), 1279-1293, 2014 | 673 | 2014 |
Dual role of autophagy in hallmarks of cancer SS Singh, S Vats, AYQ Chia, TZ Tan, S Deng, MS Ong, F Arfuso, CT Yap, ... Oncogene 37 (9), 1142-1158, 2018 | 499 | 2018 |
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor … RYJ Huang, MK Wong, TZ Tan, KT Kuay, AHC Ng, VY Chung, YS Chu, ... Cell death & disease 4 (11), e915-e915, 2013 | 431 | 2013 |
Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell–mediated lysis I Akalay, B Janji, M Hasmim, MZ Noman, F André, P De Cremoux, ... Cancer research 73 (8), 2418-2427, 2013 | 325 | 2013 |
Molecular subtypes of urothelial bladder cancer: results from a meta-cohort analysis of 2411 tumors TZ Tan, M Rouanne, KT Tan, RYJ Huang, JP Thiery European urology 75 (3), 423-432, 2019 | 253 | 2019 |
The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200 MZ Noman, B Janji, A Abdou, M Hasmim, S Terry, TZ Tan, ... Oncoimmunology 6 (1), e1263412, 2017 | 237 | 2017 |
Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer TZ Tan, QH Miow, RYJ Huang, MK Wong, J Ye, JA Lau, MC Wu, ... EMBO molecular medicine 5 (7), 1051-1066, 2013 | 222 | 2013 |
Lgr5 marks stem/progenitor cells in ovary and tubal epithelia A Ng, S Tan, G Singh, P Rizk, Y Swathi, TZ Tan, RYJ Huang, ... Nature cell biology 16 (8), 745-757, 2014 | 219 | 2014 |
Molecular characterization of breast cancer CTCs associated with brain metastasis D Boral, M Vishnoi, HN Liu, W Yin, ML Sprouse, A Scamardo, DS Hong, ... Nature communications 8 (1), 196, 2017 | 189 | 2017 |
Short-term expansion of breast circulating cancer cells predicts response to anti-cancer therapy BL Khoo, SC Lee, P Kumar, TZ Tan, ME Warkiani, SGW Ow, S Nandi, ... Oncotarget 6 (17), 15578, 2015 | 171 | 2015 |
DEAD-box helicase DP103 defines metastatic potential of human breast cancers EM Shin, HS Hay, MH Lee, JN Goh, TZ Tan, YP Sen, SW Lim, EM Yousef, ... The Journal of clinical investigation 124 (9), 3807-3824, 2014 | 158 | 2014 |
GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification VY Chung, TZ Tan, M Tan, MK Wong, KT Kuay, Z Yang, J Ye, J Muller, ... Scientific reports 6 (1), 19943, 2016 | 153 | 2016 |
A novel cognitive interpretation of breast cancer thermography with complementary learning fuzzy neural memory structure TZ Tan, C Quek, GS Ng, EYK Ng Expert Systems with Applications 33 (3), 652-666, 2007 | 151 | 2007 |
FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway M Asad, MK Wong, TZ Tan, M Choolani, J Low, S Mori, D Virshup, ... Cell death & disease 5 (7), e1346-e1346, 2014 | 141 | 2014 |
Epithelial-to-mesenchymal transition is a cause of both intrinsic and acquired resistance to KRAS G12C inhibitor in KRAS G12C–mutant non–small cell lung cancer Y Adachi, K Ito, Y Hayashi, R Kimura, TZ Tan, R Yamaguchi, H Ebi Clinical Cancer Research 26 (22), 5962-5973, 2020 | 139 | 2020 |
Epithelial–mesenchymal status renders differential responses to cisplatin in ovarian cancer QH Miow, TZ Tan, J Ye, JA Lau, T Yokomizo, JP Thiery, S Mori Oncogene 34 (15), 1899-1907, 2015 | 128 | 2015 |
TRPV4 regulates breast cancer cell extravasation, stiffness and actin cortex WH Lee, LY Choong, NN Mon, SY Lu, Q Lin, B Pang, B Yan, VSR Krishna, ... Scientific reports 6 (1), 27903, 2016 | 122 | 2016 |
The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype–specific therapeutic target for ovarian cancer J Antony, TZ Tan, Z Kelly, J Low, M Choolani, C Recchi, H Gabra, ... Science signaling 9 (448), ra97-ra97, 2016 | 112 | 2016 |
A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets D Jia, Z Liu, N Deng, TZ Tan, RYJ Huang, B Taylor-Harding, DJ Cheon, ... Cancer letters 382 (2), 203-214, 2016 | 111 | 2016 |
Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects CQ Wang, V Krishnan, LS Tay, DWL Chin, CP Koh, JY Chooi, GSS Nah, ... Cell reports 8 (3), 767-782, 2014 | 104 | 2014 |