SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function NL Price, AP Gomes, AJY Ling, FV Duarte, A Martin-Montalvo, BJ North, ... Cell metabolism 15 (5), 675-690, 2012 | 1628 | 2012 |
Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network TJ McHugh, MW Jones, JJ Quinn, N Balthasar, R Coppari, JK Elmquist, ... Science 317 (5834), 94-99, 2007 | 1122 | 2007 |
Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis N Balthasar, R Coppari, J McMinn, SM Liu, CE Lee, V Tang, CD Kenny, ... Neuron 42 (6), 983-991, 2004 | 1041 | 2004 |
Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis H Dhillon, JM Zigman, C Ye, CE Lee, RA McGovern, V Tang, CD Kenny, ... Neuron 49 (2), 191-203, 2006 | 856 | 2006 |
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity LE Parton, CP Ye, R Coppari, PJ Enriori, B Choi, CY Zhang, C Xu, ... Nature 449 (7159), 228-232, 2007 | 796 | 2007 |
Mice lacking ghrelin receptors resist the development of diet-induced obesity JM Zigman, Y Nakano, R Coppari, N Balthasar, JN Marcus, CE Lee, ... The Journal of clinical investigation 115 (12), 3564-3572, 2005 | 733 | 2005 |
The hypothalamic arcuate nucleus: a key site for mediating leptin’s effects on glucose homeostasis and locomotor activity R Coppari, M Ichinose, CE Lee, AE Pullen, CD Kenny, RA McGovern, ... Cell metabolism 1 (1), 63-72, 2005 | 563 | 2005 |
Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis JK Elmquist, R Coppari, N Balthasar, M Ichinose, BB Lowell Journal of Comparative Neurology 493 (1), 63-71, 2005 | 487 | 2005 |
Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility JW Hill, CF Elias, M Fukuda, KW Williams, ED Berglund, WL Holland, ... Cell metabolism 11 (4), 286-297, 2010 | 451 | 2010 |
Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice JW Hill, KW Williams, C Ye, J Luo, N Balthasar, R Coppari, MA Cowley, ... The Journal of clinical investigation 118 (5), 1796-1805, 2008 | 385 | 2008 |
Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice ED Berglund, CR Vianna, J Donato, MH Kim, JC Chuang, CE Lee, ... The Journal of clinical investigation 122 (3), 1000-1009, 2012 | 372 | 2012 |
Leptin’s effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons J Donato, RM Cravo, R Frazão, L Gautron, MM Scott, J Lachey, IA Castro, ... The Journal of clinical investigation 121 (1), 355-368, 2011 | 370 | 2011 |
EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses M Lazarus, K Yoshida, R Coppari, CE Bass, T Mochizuki, BB Lowell, ... Nature neuroscience 10 (9), 1131-1133, 2007 | 364 | 2007 |
Brain SIRT1: anatomical distribution and regulation by energy availability G Ramadori, CE Lee, AL Bookout, S Lee, KW Williams, J Anderson, ... Journal of Neuroscience 28 (40), 9989-9996, 2008 | 360 | 2008 |
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity L Plum, X Ma, B Hampel, N Balthasar, R Coppari, H Münzberg, ... The Journal of clinical investigation 116 (7), 1886-1901, 2006 | 360 | 2006 |
Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion E Van De Wall, R Leshan, AW Xu, N Balthasar, R Coppari, SM Liu, YH Jo, ... Endocrinology 149 (4), 1773-1785, 2008 | 354 | 2008 |
Leptin revisited: its mechanism of action and potential for treating diabetes R Coppari, C Bjørbæk Nature reviews Drug discovery 11 (9), 692-708, 2012 | 353 | 2012 |
A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions A Mazzocca, R Coppari, R De Franco, JY Cho, TA Libermann, M Pinzani, ... Cancer research 65 (11), 4728-4738, 2005 | 271 | 2005 |
Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells P Kievit, JK Howard, MK Badman, N Balthasar, R Coppari, H Mori, ... Cell metabolism 4 (2), 123-132, 2006 | 268 | 2006 |
Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice T Fujikawa, JC Chuang, I Sakata, G Ramadori, R Coppari Proceedings of the National Academy of Sciences 107 (40), 17391-17396, 2010 | 253 | 2010 |