The effects of substrate stiffness on the in vitro activation of macrophages and in vivo host response to poly (ethylene glycol)-based hydrogels AK Blakney, MD Swartzlander, SJ Bryant Journal of biomedical materials research. Part A 100 (6), 1375, 2012 | 513 | 2012 |
Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice PF McKay, K Hu, AK Blakney, K Samnuan, JC Brown, R Penn, J Zhou, ... Nature communications 11 (1), 3523, 2020 | 417 | 2020 |
Microbial composition predicts genital tract inflammation and persistent bacterial vaginosis in South African adolescent females K Lennard, S Dabee, SL Barnabas, E Havyarimana, A Blakney, ... Infection and immunity 86 (1), 10.1128/iai. 00410-17, 2018 | 185 | 2018 |
Linking the foreign body response and protein adsorption to PEG-based hydrogels using proteomics MD Swartzlander, CA Barnes, AK Blakney, JL Kaar, TR Kyriakides, ... Biomaterials 41, 26-36, 2015 | 183 | 2015 |
Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA AK Blakney, PF McKay, BI Yus, Y Aldon, RJ Shattock Gene therapy 26 (9), 363-372, 2019 | 174 | 2019 |
An update on self-amplifying mRNA vaccine development AK Blakney, S Ip, AJ Geall Vaccines 9 (2), 97, 2021 | 169 | 2021 |
Immunomodulation by mesenchymal stem cells combats the foreign body response to cell-laden synthetic hydrogels MD Swartzlander, AK Blakney, LD Amer, KD Hankenson, TR Kyriakides, ... Biomaterials 41, 79-88, 2015 | 152 | 2015 |
Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice AJ Spencer, PF McKay, S Belij-Rammerstorfer, M Ulaszewska, CD Bissett, ... Nature communications 12 (1), 2893, 2021 | 128 | 2021 |
Big is beautiful: enhanced saRNA delivery and immunogenicity by a higher molecular weight, bioreducible, cationic polymer AK Blakney, Y Zhu, PF McKay, CR Bouton, J Yeow, J Tang, K Hu, ... ACS nano 14 (5), 5711-5727, 2020 | 125 | 2020 |
Electrospun fibers for vaginal anti-HIV drug delivery AK Blakney, C Ball, EA Krogstad, KA Woodrow Antiviral research 100, S9-S16, 2013 | 117 | 2013 |
Delivery of multipurpose prevention drug combinations from electrospun nanofibers using composite microarchitectures AK Blakney, EA Krogstad, YH Jiang, KA Woodrow International journal of nanomedicine, 2967-2978, 2014 | 95 | 2014 |
Temporal progression of the host response to implanted poly (ethylene glycol)‐based hydrogels AD Lynn, AK Blakney, TR Kyriakides, SJ Bryant Journal of Biomedical Materials Research Part A 96 (4), 621-631, 2011 | 91 | 2011 |
Neutrophils enable local and non‐invasive liposome delivery to inflamed skeletal muscle and ischemic heart J Che, A Najer, AK Blakney, PF McKay, M Bellahcene, CW Winter, ... Advanced Materials 32 (48), 2003598, 2020 | 81 | 2020 |
One size does not fit all: the effect of chain length and charge density of poly (ethylene imine) based copolymers on delivery of pDNA, mRNA, and RepRNA polyplexes AK Blakney, G Yilmaz, PF McKay, CR Becer, RJ Shattock Biomacromolecules 19 (7), 2870-2879, 2018 | 72 | 2018 |
Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines AK Blakney, PF McKay, K Hu, K Samnuan, N Jain, A Brown, A Thomas, ... Journal of controlled release 338, 201-210, 2021 | 65 | 2021 |
Nanoparticle-releasing nanofiber composites for enhanced in vivo vaginal retention EA Krogstad, R Ramanathan, C Nhan, JC Kraft, AK Blakney, S Cao, ... Biomaterials 144, 1-16, 2017 | 62 | 2017 |
Current status and future perspectives on MRNA drug manufacturing C Webb, S Ip, NV Bathula, P Popova, SKV Soriano, HH Ly, B Eryilmaz, ... Molecular Pharmaceutics 19 (4), 1047-1058, 2022 | 59 | 2022 |
Innate inhibiting proteins enhance expression and immunogenicity of self-amplifying RNA AK Blakney, PF McKay, CR Bouton, K Hu, K Samnuan, RJ Shattock Molecular Therapy 29 (3), 1174-1185, 2021 | 52 | 2021 |
Effect of tissue microenvironment on fibrous capsule formation to biomaterial-coated implants JL Hernandez, J Park, S Yao, AK Blakney, HV Nguyen, BH Katz, ... Biomaterials 273, 120806, 2021 | 51 | 2021 |
The skin you are in: design-of-experiments optimization of lipid nanoparticle self-amplifying RNA formulations in human skin explants AK Blakney, PF McKay, B Ibarzo Yus, JE Hunter, EA Dex, RJ Shattock ACS nano 13 (5), 5920-5930, 2019 | 51 | 2019 |