| Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer A Aghdassi, M Sendler, A Guenther, J Mayerle, CO Behn, CD Heidecke, ... Gut 61 (3), 439-448, 2012 | 327 | 2012 |
| Genetics, cell biology, and pathophysiology of pancreatitis J Mayerle, M Sendler, E Hegyi, G Beyer, MM Lerch, M Sahin-Tóth Gastroenterology 156 (7), 1951-1968. e1, 2019 | 307 | 2019 |
| NLRP3 inflammasome regulates development of systemic inflammatory response and compensatory anti-inflammatory response syndromes in mice with acute pancreatitis M Sendler, C van den Brandt, J Glaubitz, A Wilden, J Golchert, FU Weiss, ... Gastroenterology 158 (1), 253-269. e14, 2020 | 251 | 2020 |
| Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice M Sendler, A Dummer, FU Weiss, B Krüger, T Wartmann, ... Gut 62 (3), 430-439, 2013 | 248 | 2013 |
| Cathepsin B-mediated activation of trypsinogen in endocytosing macrophages increases severity of pancreatitis in mice M Sendler, FU Weiss, J Golchert, G Homuth, C van den Brandt, ... Gastroenterology 154 (3), 704-718. e10, 2018 | 234 | 2018 |
| Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling M Hohwieler, A Illing, PC Hermann, T Mayer, M Stockmann, L Perkhofer, ... Gut 66 (3), 473-486, 2017 | 223 | 2017 |
| Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis J Maléth, A Balázs, P Pallagi, Z Balla, B Kui, M Katona, L Judák, I Németh, ... Gastroenterology 148 (2), 427-439. e16, 2015 | 216 | 2015 |
| A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis K Fjeld, FU Weiss, D Lasher, J Rosendahl, JM Chen, BB Johansson, ... Nature genetics 47 (5), 518-522, 2015 | 208 | 2015 |
| Immune cell and stromal signature associated with progression-free survival of patients with resected pancreatic ductal adenocarcinoma UM Mahajan, E Langhoff, E Goni, E Costello, W Greenhalf, C Halloran, ... Gastroenterology 155 (5), 1625-1639. e2, 2018 | 172 | 2018 |
| Animal models for investigating chronic pancreatitis AA Aghdassi, J Mayerle, S Christochowitz, FU Weiss, M Sendler, ... Fibrogenesis & tissue repair 4, 1-16, 2011 | 162 | 2011 |
| Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice T Wartmann, J Mayerle, T Kähne, M Sahin–Tóth, M Ruthenbürger, ... Gastroenterology 138 (2), 726-737, 2010 | 161 | 2010 |
| Lysosome-associated membrane proteins (LAMP) maintain pancreatic acinar cell homeostasis: LAMP-2–deficient mice develop pancreatitis OA Mareninova, M Sendler, SR Malla, I Yakubov, SW French, ... Cellular and molecular gastroenterology and hepatology 1 (6), 678-694, 2015 | 133 | 2015 |
| Chronic stress increases experimental pancreatic cancer growth, reduces survival and can be antagonised by beta-adrenergic receptor blockade LI Partecke, S Speerforck, A Käding, F Seubert, S Kühn, E Lorenz, ... Pancreatology 16 (3), 423-433, 2016 | 131 | 2016 |
| Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function F Frost, T Kacprowski, M Rühlemann, M Pietzner, C Bang, A Franke, ... Gut 70 (3), 522-530, 2021 | 119 | 2021 |
| Cathepsin B activity initiates apoptosis via digestive protease activation in pancreatic acinar cells and experimental pancreatitis M Sendler, S Maertin, D John, M Persike, FU Weiss, B Krüger, ... Journal of Biological Chemistry 291 (28), 14717-14731, 2016 | 115 | 2016 |
| Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus A Mahajan, X Sim, HJ Ng, A Manning, MA Rivas, HM Highland, AE Locke, ... PLoS genetics 11 (1), e1004876, 2015 | 115 | 2015 |
| Impaired exocrine pancreatic function associates with changes in intestinal microbiota composition and diversity F Frost, T Kacprowski, M Rühlemann, R Bülow, JP Kühn, A Franke, ... Gastroenterology 156 (4), 1010-1015, 2019 | 106 | 2019 |
| Complement component 5 mediates development of fibrosis, via activation of stellate cells, in 2 mouse models of chronic pancreatitis M Sendler, G Beyer, UM Mahajan, V Kauschke, S Maertin, C Schurmann, ... Gastroenterology 149 (3), 765-776. e10, 2015 | 101 | 2015 |
| A syngeneic orthotopic murine model of pancreatic adenocarcinoma in the C57/BL6 mouse using the Panc02 and 6606PDA cell lines LI Partecke, M Sendler, A Kaeding, FU Weiss, J Mayerle, A Dummer, ... European Surgical Research 47 (2), 98-107, 2011 | 91 | 2011 |
| Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer UM Mahajan, S Teller, M Sendler, R Palankar, C van den Brandt, ... Gut 65 (11), 1838-1849, 2016 | 90 | 2016 |
