The ATM–Chk2–Cdc25A checkpoint pathway guards against radioresistant DNA synthesis J Falck, N Mailand, RG Syljuåsen, J Bartek, J Lukas Nature 410 (6830), 842-847, 2001 | 1502 | 2001 |
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins N Mailand, S Bekker-Jensen, H Faustrup, F Melander, J Bartek, C Lukas, ... Cell 131 (5), 887-900, 2007 | 1354 | 2007 |
Rapid destruction of human Cdc25A in response to DNA damage N Mailand, J Falck, C Lukas, RG Syljuåsen, M Welcker, J Bartek, J Lukas Science 288 (5470), 1425-1429, 2000 | 1075 | 2000 |
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins C Doil, N Mailand, S Bekker-Jensen, P Menard, DH Larsen, R Pepperkok, ... Cell 136 (3), 435-446, 2009 | 1065 | 2009 |
ATR prohibits replication catastrophe by preventing global exhaustion of RPA LI Toledo, M Altmeyer, MB Rask, C Lukas, DH Larsen, LK Povlsen, ... Cell 155 (5), 1088-1103, 2013 | 883 | 2013 |
Regulation of G2/M events by Cdc25A through phosphorylation‐dependent modulation of its stability N Mailand, AV Podtelejnikov, A Groth, M Mann, J Bartek, J Lukas The EMBO journal, 2002 | 471 | 2002 |
DNA repair network analysis reveals shieldin as a key regulator of NHEJ and PARP inhibitor sensitivity R Gupta, K Somyajit, T Narita, E Maskey, A Stanlie, M Kremer, D Typas, ... Cell 173 (4), 972-988. e23, 2018 | 429 | 2018 |
Regulation of PCNA–protein interactions for genome stability N Mailand, I Gibbs-Seymour, S Bekker-Jensen Nature reviews Molecular cell biology 14 (5), 269-282, 2013 | 420 | 2013 |
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage T Thorslund, A Ripplinger, S Hoffmann, T Wild, M Uckelmann, ... Nature 527 (7578), 389-393, 2015 | 416 | 2015 |
CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis N Mailand, JFX Diffley Cell 122 (6), 915-926, 2005 | 415 | 2005 |
Centrosome-associated Chk1 prevents premature activation of cyclin-B–Cdk1 kinase A Krämer, N Mailand, C Lukas, RG Syljuåsen, CJ Wilkinson, EA Nigg, ... Nature cell biology 6 (9), 884-891, 2004 | 409 | 2004 |
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity RB Damgaard, U Nachbur, M Yabal, WWL Wong, BK Fiil, M Kastirr, ... Molecular cell 46 (6), 746-758, 2012 | 407 | 2012 |
Assembly and function of DNA double-strand break repair foci in mammalian cells S Bekker-Jensen, N Mailand DNA repair 9 (12), 1219-1228, 2010 | 402 | 2010 |
Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers P Schwertman, S Bekker-Jensen, N Mailand Nature reviews Molecular cell biology 17 (6), 379-394, 2016 | 383 | 2016 |
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes S Bekker-Jensen, JR Danielsen, K Fugger, I Gromova, A Nerstedt, ... Nature cell biology 12 (1), 80-86, 2010 | 367 | 2010 |
Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level JMR Danielsen, KB Sylvestersen, S Bekker-Jensen, D Szklarczyk, ... Molecular & Cellular Proteomics 10 (3), 2011 | 366 | 2011 |
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes T Gudjonsson, M Altmeyer, V Savic, L Toledo, C Dinant, M Grøfte, ... Cell 150 (4), 697-709, 2012 | 351 | 2012 |
The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks M Meerang, D Ritz, S Paliwal, Z Garajova, M Bosshard, N Mailand, ... Nature cell biology 13 (11), 1376-1382, 2011 | 311 | 2011 |
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass LK Povlsen, P Beli, SA Wagner, SL Poulsen, KB Sylvestersen, ... Nature cell biology 14 (10), 1089-1098, 2012 | 300 | 2012 |
Destruction of Claspin by SCFβTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress N Mailand, S Bekker-Jensen, J Bartek, J Lukas Molecular cell 23 (3), 307-318, 2006 | 298 | 2006 |