New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo CK Bullen, GM Laird, CM Durand, JD Siliciano, RF Siliciano Nature medicine 20 (4), 425-429, 2014 | 561 | 2014 |
Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations GM Laird, CK Bullen, DIS Rosenbloom, AR Martin, AL Hill, CM Durand, ... The Journal of clinical investigation 125 (5), 1901-1912, 2015 | 425 | 2015 |
Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation HC Yang, S Xing, L Shan, K O’Connell, J Dinoso, A Shen, Y Zhou, ... The Journal of clinical investigation 119 (11), 3473-3486, 2009 | 305 | 2009 |
Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation S Xing, CK Bullen, NS Shroff, L Shan, HC Yang, JL Manucci, S Bhat, ... Journal of virology 85 (12), 6060-6064, 2011 | 238 | 2011 |
A quantitative basis for antiretroviral therapy for HIV-1 infection BL Jilek, M Zarr, ME Sampah, SA Rabi, CK Bullen, J Lai, L Shen, ... Nature medicine 18 (3), 446-451, 2012 | 179 | 2012 |
Infectability of human BrainSphere neurons suggests neurotropism of SARS-CoV-2 CK Bullen, HT Hogberg, A Bahadirli-Talbott, WR Bishai, T Hartung, ... ALTEX-Alternatives to animal experimentation 37 (4), 665-671, 2020 | 166 | 2020 |
Stimulated nuclear translocation of NF-κB and shuttling differentially depend on dynein and the dynactin complex CK Shrum, D Defrancisco, MK Meffert Proceedings of the National Academy of Sciences 106 (8), 2647-2652, 2009 | 107 | 2009 |
Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma LS Cheung, J Fu, P Kumar, A Kumar, ME Urbanowski, EA Ihms, ... Proceedings of the National Academy of Sciences 116 (8), 3100-3105, 2019 | 64 | 2019 |
Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice AA Ordonez, CK Bullen, AF Villabona-Rueda, EA Thompson, ML Turner, ... Communications biology 5 (1), 242, 2022 | 62 | 2022 |
A primary CD4+ T cell model of HIV-1 latency established after activation through the T cell receptor and subsequent return to quiescence M Kim, NN Hosmane, CK Bullen, A Capoferri, HC Yang, JD Siliciano, ... Nature protocols 9 (12), 2755-2770, 2014 | 58 | 2014 |
HSF1 inhibition attenuates HIV-1 latency reversal mediated by several candidate LRAs In Vitro and Ex Vivo A Timmons, E Fray, M Kumar, F Wu, W Dai, CK Bullen, P Kim, C Hetzel, ... Proceedings of the National Academy of Sciences 117 (27), 15763-15771, 2020 | 29 | 2020 |
Quantification of infectious SARS-CoV-2 by the 50% tissue culture infectious dose endpoint dilution assay CK Bullen, SL Davis, MM Looney SARS-CoV-2: Methods and Protocols, 131-146, 2022 | 18 | 2022 |
Allogeneic bone marrow transplantation with post-transplant cyclophosphamide for patients with HIV and haematological malignancies: a feasibility study CM Durand, AA Capoferri, AD Redd, M Zahurak, DIS Rosenbloom, ... The Lancet HIV 7 (9), e602-e610, 2020 | 14 | 2020 |
Nucleolin mediates SARS-CoV-2 replication and viral-induced apoptosis of host cells VF Merino, Y Yan, AA Ordonez, CK Bullen, A Lee, H Saeki, K Ray, ... Antiviral research 211, 105550, 2023 | 11 | 2023 |
Methods of producing aggregate-free monomeric diphtheria toxin fusion proteins and therapeutic uses WR Bishai, JR Murphy, L Cheung, S Gupta, CK Bullen US Patent 10,988,512, 2021 | 11 | 2021 |
Relative and Quantitative Phosphoproteome Analysis of Macrophages in Response to Infection by Virulent and Avirulent Mycobacteria Reveals a Distinct Role of the Cytosolic … E Choudhary, CK Bullen, R Goel, AK Singh, M Praharaj, P Thakur, ... Journal of proteome research 19 (6), 2316-2336, 2020 | 11 | 2020 |
Intravenous BCG vaccination reduces SARS-CoV-2 severity and promotes extensive reprogramming of lung immune cells AK Singh, R Wang, KA Lombardo, M Praharaj, CK Bullen, P Um, M Gupta, ... Iscience 26 (10), 2023 | 7 | 2023 |
The NF-κB family in learning and memory CK Shrum, MK Meffert Learning and memory: a comprehensive reference, 567-585, 2007 | 7 | 2007 |
MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival CK Bullen, AK Singh, S Krug, S Lun, P Thakur, G Srikrishna, WR Bishai JCI insight 8 (20), 2023 | 6 | 2023 |
Genome editing of human embryos: to edit or not to edit, that is the question S Chandrasegaran, CK Bullen, D Carroll The Journal of Clinical Investigation 127 (10), 3588-3590, 2017 | 5 | 2017 |