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Amal Elnaggar
Amal Elnaggar
University of British Columbia, BC Cancer Research Centre and Menoufia University
在 bccrc.ca 的电子邮件经过验证
标题
引用次数
引用次数
年份
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation
G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ...
Cell 153 (5), 1064-1079, 2013
4472013
Translational activation of HIF1α by YB-1 promotes sarcoma metastasis
AM El-Naggar, CJ Veinotte, H Cheng, TGP Grunewald, GL Negri, ...
Cancer cell 27 (5), 682-697, 2015
3292015
YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1
SP Somasekharan, A El-Naggar, G Leprivier, H Cheng, S Hajee, ...
Journal of Cell Biology 208 (7), 913-929, 2015
3052015
Class I HDAC inhibitors enhance YB‐1 acetylation and oxidative stress to block sarcoma metastasis
AM El‐Naggar, SP Somasekharan, Y Wang, H Cheng, GL Negri, M Pan, ...
EMBO reports 20 (12), e48375, 2019
952019
ERBB 4 confers metastatic capacity in ewing sarcoma
A Mendoza‐Naranjo, A El‐Naggar, DH Wai, P Mistry, N Lazic, FRR Ayala, ...
EMBO molecular medicine 5 (7), 1087-1102, 2013
842013
Translational control of aberrant stress responses as a hallmark of cancer
AM El‐Naggar, PH Sorensen
The Journal of pathology 244 (5), 650-666, 2018
812018
Oncofetal chondroitin sulfate glycosaminoglycans are key players in integrin signaling and tumor cell motility
TM Clausen, MA Pereira, N Al Nakouzi, HZ Oo, MØ Agerbæk, S Lee, ...
Molecular Cancer Research 14 (12), 1288-1299, 2016
702016
Single-cell transcriptomic analysis of endometriosis
MAS Fonseca, M Haro, KN Wright, X Lin, F Abbasi, J Sun, L Hernandez, ...
Nature genetics 55 (2), 255-267, 2023
672023
Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in Ewing sarcoma
HF Zhang, CS Hughes, W Li, JZ He, D Surdez, AM El-Naggar, H Cheng, ...
Cancer discovery 11 (11), 2884-2903, 2021
672021
Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma
GL Negri, BM Grande, A Delaidelli, A El‐Naggar, D Cochrane, CC Lau, ...
The Journal of pathology 249 (3), 319-331, 2019
462019
Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation
A Mazloomian, S Araki, M Ohori, AM El-Naggar, D Yap, A Bashashati, ...
Communications biology 2 (1), 165, 2019
442019
Expression and stability of hypoxia inducible factor 1α in osteosarcoma
A El Naggar, P Clarkson, F Zhang, J Mathers, C Tognon, PH Sorensen
Pediatric blood & cancer 59 (7), 1215-1222, 2012
432012
HACE1 is a potential tumor suppressor in osteosarcoma
AM El-Naggar, PW Clarkson, GL Negri, B Turgu, F Zhang, MS Anglesio, ...
Cell death & disease 10 (1), 21, 2019
362019
An aqueous extract of marine microalgae exhibits antimetastatic activity through preferential killing of suspended cancer cells and anticolony forming activity
SP Somasekharan, A El-Naggar, PH Sorensen, Y Wang, H Cheng
Evidence‐Based Complementary and Alternative Medicine 2016 (1), 9730654, 2016
352016
MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation
A Delaidelli, GL Negri, A Jan, B Jansonius, A El-Naggar, JKM Lim, ...
Cell Death & Differentiation 24 (9), 1564-1576, 2017
312017
HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases
M Kogler, L Tortola, GL Negri, A Leopoldi, AM El-Naggar, S Mereiter, ...
Cancer research 80 (14), 3009-3022, 2020
252020
Modelling hereditary diffuse gastric cancer initiation using transgenic mouse‐derived gastric organoids and single‐cell sequencing
K Dixon, T Brew, D Farnell, TD Godwin, S Cheung, C Chow, M Ta, G Ho, ...
The Journal of Pathology 254 (3), 254-264, 2021
182021
Surface and global proteome analyses identify ENPP1 and other surface proteins as actionable immunotherapeutic targets in Ewing sarcoma
B Mooney, GL Negri, T Shyp, A Delaidelli, HF Zhang, SE Spencer Miko, ...
Clinical Cancer Research 30 (5), 1022-1037, 2024
122024
De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer
S Lefort, A El-Naggar, S Tan, S Colborne, GL Negri, D Pellacani, M Hirst, ...
Cell Death & Differentiation 29 (1), 54-64, 2022
72022
HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner
B Turgu, F Zhang, A El-Naggar, GL Negri, M Kogler, L Tortola, F Johnson, ...
Oncogene 40 (11), 1988-2001, 2021
62021
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