The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ... Cell 153 (5), 1064-1079, 2013 | 447 | 2013 |
Translational activation of HIF1α by YB-1 promotes sarcoma metastasis AM El-Naggar, CJ Veinotte, H Cheng, TGP Grunewald, GL Negri, ... Cancer cell 27 (5), 682-697, 2015 | 329 | 2015 |
YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1 SP Somasekharan, A El-Naggar, G Leprivier, H Cheng, S Hajee, ... Journal of Cell Biology 208 (7), 913-929, 2015 | 305 | 2015 |
Class I HDAC inhibitors enhance YB‐1 acetylation and oxidative stress to block sarcoma metastasis AM El‐Naggar, SP Somasekharan, Y Wang, H Cheng, GL Negri, M Pan, ... EMBO reports 20 (12), e48375, 2019 | 95 | 2019 |
ERBB 4 confers metastatic capacity in ewing sarcoma A Mendoza‐Naranjo, A El‐Naggar, DH Wai, P Mistry, N Lazic, FRR Ayala, ... EMBO molecular medicine 5 (7), 1087-1102, 2013 | 84 | 2013 |
Translational control of aberrant stress responses as a hallmark of cancer AM El‐Naggar, PH Sorensen The Journal of pathology 244 (5), 650-666, 2018 | 81 | 2018 |
Oncofetal chondroitin sulfate glycosaminoglycans are key players in integrin signaling and tumor cell motility TM Clausen, MA Pereira, N Al Nakouzi, HZ Oo, MØ Agerbæk, S Lee, ... Molecular Cancer Research 14 (12), 1288-1299, 2016 | 70 | 2016 |
Single-cell transcriptomic analysis of endometriosis MAS Fonseca, M Haro, KN Wright, X Lin, F Abbasi, J Sun, L Hernandez, ... Nature genetics 55 (2), 255-267, 2023 | 67 | 2023 |
Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in Ewing sarcoma HF Zhang, CS Hughes, W Li, JZ He, D Surdez, AM El-Naggar, H Cheng, ... Cancer discovery 11 (11), 2884-2903, 2021 | 67 | 2021 |
Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma GL Negri, BM Grande, A Delaidelli, A El‐Naggar, D Cochrane, CC Lau, ... The Journal of pathology 249 (3), 319-331, 2019 | 46 | 2019 |
Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation A Mazloomian, S Araki, M Ohori, AM El-Naggar, D Yap, A Bashashati, ... Communications biology 2 (1), 165, 2019 | 44 | 2019 |
Expression and stability of hypoxia inducible factor 1α in osteosarcoma A El Naggar, P Clarkson, F Zhang, J Mathers, C Tognon, PH Sorensen Pediatric blood & cancer 59 (7), 1215-1222, 2012 | 43 | 2012 |
HACE1 is a potential tumor suppressor in osteosarcoma AM El-Naggar, PW Clarkson, GL Negri, B Turgu, F Zhang, MS Anglesio, ... Cell death & disease 10 (1), 21, 2019 | 36 | 2019 |
An aqueous extract of marine microalgae exhibits antimetastatic activity through preferential killing of suspended cancer cells and anticolony forming activity SP Somasekharan, A El-Naggar, PH Sorensen, Y Wang, H Cheng Evidence‐Based Complementary and Alternative Medicine 2016 (1), 9730654, 2016 | 35 | 2016 |
MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation A Delaidelli, GL Negri, A Jan, B Jansonius, A El-Naggar, JKM Lim, ... Cell Death & Differentiation 24 (9), 1564-1576, 2017 | 31 | 2017 |
HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases M Kogler, L Tortola, GL Negri, A Leopoldi, AM El-Naggar, S Mereiter, ... Cancer research 80 (14), 3009-3022, 2020 | 25 | 2020 |
Modelling hereditary diffuse gastric cancer initiation using transgenic mouse‐derived gastric organoids and single‐cell sequencing K Dixon, T Brew, D Farnell, TD Godwin, S Cheung, C Chow, M Ta, G Ho, ... The Journal of Pathology 254 (3), 254-264, 2021 | 18 | 2021 |
Surface and global proteome analyses identify ENPP1 and other surface proteins as actionable immunotherapeutic targets in Ewing sarcoma B Mooney, GL Negri, T Shyp, A Delaidelli, HF Zhang, SE Spencer Miko, ... Clinical Cancer Research 30 (5), 1022-1037, 2024 | 12 | 2024 |
De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer S Lefort, A El-Naggar, S Tan, S Colborne, GL Negri, D Pellacani, M Hirst, ... Cell Death & Differentiation 29 (1), 54-64, 2022 | 7 | 2022 |
HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner B Turgu, F Zhang, A El-Naggar, GL Negri, M Kogler, L Tortola, F Johnson, ... Oncogene 40 (11), 1988-2001, 2021 | 6 | 2021 |